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| Name | Pos | Team | Age | DOB | POB | Nationality | Bats | Throws | Height | Weight | Salary |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Santamarina, Doug | SP | St. Louis Coeur | 29 | 06/11/2027 | Belize | BLZ | Switch | Right | 6' 4" | 200 lbs | $10,500,000 |
| Santiago, Pedro | C | Free Agent | 16 | 03/08/2040 | Jicomé | DOM | Right | Right | 6' 1" | 185 lbs | - |
| Santos, Luis | 2B | Free Agent | 33 | 09/14/2023 | Holguín | CUB | Right | Right | 6' 0" | 200 lbs | - |
| Santos, Pepe | 1B | New Orleans Voodoo | 24 | 06/22/2032 | Pedro Brand | DOM | Left | Left | 6' 8" | 200 lbs | $280,000 |
| Sasaki, Tadahisa | C | Free Agent | 16 | 04/28/2040 | Sapporo | JPN | Left | Right | 6' 3" | 190 lbs | - |
| Saunders, David | RF | Long Island Lighthouse | 28 | 08/26/2028 | Plymouth | USA | Left | Left | 6' 3" | 200 lbs | $3,200,000 |
| Saunders, Joe | CF | St. Louis Coeur | 26 | 07/24/2030 | Sanford | USA | Left | Left | 6' 0" | 200 lbs | $280,000 |
| Searle, Ron | SP | Free Agent | 23 | 08/11/2033 | Toronto | CAN | Right | Right | 6' 1" | 195 lbs | - |
| Serrano, Jesús | 1B | Long Island Lighthouse | 26 | 04/23/2030 | Tegucigalpa | HON | Right | Right | 6' 4" | 195 lbs | $14,440,000 |
| Shan, San-pao | SP | Free Agent | 16 | 09/12/2040 | Homei | TPE | Right | Right | 6' 2" | 180 lbs | - |
| Shirt, Robert | SP | Panama City Piranhas | 33 | 12/05/2023 | Spanish Town | JAM | Right | Right | 5' 11" | 200 lbs | $420,000 |
| Shrisha, Shripati | SP | Long Island Lighthouse | 17 | 07/25/2039 | Qutubullapur | IND | Right | Right | 6' 1" | 175 lbs | - |
| Shuker, Alexander | SP | Free Agent | 16 | 05/09/2040 | Savanna la Mar | JAM | Right | Right | 6' 7" | 200 lbs | - |
| Silva, Gilberto | RF | Boston Patriots | 26 | 11/05/2030 | San Alejo | SLV | Right | Right | 6' 2" | 180 lbs | $280,000 |
| Slaymaker, Lance | C | Boston Patriots | 27 | 03/04/2029 | Akron | USA | Right | Right | 6' 0" | 200 lbs | $330,000 |
| Smulders, Jasper | RP | Athletic Club KC | 32 | 10/05/2024 | Rotterdam | NED | Left | Right | 5' 10" | 190 lbs | $1,000,000 |
| Smythe, Dean | C | Free Agent | 17 | 03/01/2039 | Foxton | NZL | Left | Right | 6' 2" | 195 lbs | - |
| Son, Kyung-chul | 2B | New Orleans Voodoo | 32 | 12/03/2024 | Seoul | KOR | Left | Right | 6' 0" | 185 lbs | $17,500,000 |
| Soto, Robinson | SP | Free Agent | 24 | 12/16/2032 | Mislata | ESP | Left | Left | 6' 0" | 175 lbs | - |
| Soto, Ángel | 2B | Boston Patriots | 22 | 02/15/2034 | Louisville | USA | Left | Right | 6' 0" | 175 lbs | $280,000 |
| Souza, Jorge | SP | Vancouver Grey Wolves | 36 | 09/01/2020 | Villa Vazquez | DOM | Right | Right | 6' 1" | 205 lbs | $22,000,000 |
| Spillman, Bill | SS | Vancouver Grey Wolves | 27 | 07/01/2029 | Chicago | USA | Switch | Right | 6' 0" | 200 lbs | $280,000 |
| Stanfield, Ray | 2B | Vancouver Grey Wolves | 28 | 01/14/2028 | Grayling | USA | Right | Right | 6' 2" | 200 lbs | $280,000 |
| Stansberry, Darryl | CF | Buffalo White Walkers | 25 | 09/17/2031 | San Francisco | USA | Right | Right | 6' 2" | 205 lbs | $280,000 |
| Stephens, Arthur | SP | Free Agent | 24 | 11/26/2032 | Pompton Lakes | USA | Switch | Right | 6' 2" | 205 lbs | - |
| Stockton, Andrew | RP | Panama City Piranhas | 28 | 09/08/2028 | Bodmin | ENG | Left | Left | 6' 3" | 200 lbs | $1,827,200 |
| Strong, Bill | LF | Buffalo White Walkers | 27 | 06/28/2029 | Oakland | USA | Left | Left | 6' 2" | 200 lbs | $280,000 |
| Strong, Tim | RP | New Orleans Voodoo | 33 | 02/16/2023 | Quincy | USA | Left | Left | 6' 4" | 205 lbs | $3,500,000 |
| Sulander, Antti-Jussi | RF | Seattle Rocketeers | 27 | 04/17/2029 | Kiskorös | HUN | Left | Left | 6' 1" | 195 lbs | $5,760,000 |
| Sullivan, David | RP | Boston Patriots | 29 | 07/03/2027 | Wolverine Lake | USA | Switch | Right | 6' 2" | 195 lbs | $280,000 |
| Summers, Eric | RP | Panama City Piranhas | 33 | 10/03/2023 | South Jordan | USA | Right | Right | 6' 0" | 200 lbs | $550,000 |
| Sun, Shi-min | RP | Free Agent | 16 | 09/26/2040 | Jiaozuo | CHN | Left | Right | 6' 3" | 180 lbs | - |
| Surekha, Adyota | RP | D.C. Divided | 16 | 03/02/2040 | Hyderabad | IND | Right | Right | 6' 2" | 175 lbs | - |
| Swan, Ishaan | LF | Panama City Piranhas | 30 | 01/07/2026 | St. George | BER | Left | Right | 6' 0" | 185 lbs | $13,400,100 |
| Sánchez, Jorge | C | Long Island Lighthouse | 31 | 08/09/2025 | Consuelo | DOM | Right | Right | 6' 1" | 200 lbs | $399,000 |
| Sánchez, Víctor | RF | Boston Patriots | 23 | 01/23/2033 | Cotuí | DOM | Left | Right | 6' 4" | 185 lbs | $280,000 |
