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| Name | Pos | Team | Age | DOB | POB | Nationality | Bats | Throws | Height | Weight | Salary |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Sa'id, Reda | RP | Free Agent | 19 | 11/01/2030 | Qazrin | ISR | Switch | Right | 5' 11" | 160 lbs | - |
| Sai, Arata | RP | Free Agent | 19 | 02/18/2030 | Tokyo | JPN | Right | Right | 6' 3" | 190 lbs | - |
| Salinas, Gabriel | 1B | MSL Buckhead Bowties | 17 | 08/26/2032 | Santa Cruz | ARG | Right | Right | 6' 8" | 225 lbs | - |
| Sawyer, Johnny | CF | MSL Charleston Battery | 17 | 02/07/2032 | Chattanooga | USA | Left | Left | 6' 4" | 195 lbs | - |
| Scott, Tom | 3B | MSL Kingston Township Knights | 18 | 11/12/2031 | Conroe | USA | Right | Right | 6' 1" | 190 lbs | - |
| Seletto, Bonifazio | RP | MSL Pittsburgh Kingfishers | 18 | 01/23/2031 | Rosario | ARG | Right | Right | 6' 2" | 175 lbs | - |
| Serrano, Carlos | LF | MSL Panama City Piranhas | 18 | 01/20/2031 | San José de Guanipa | VEN | Right | Right | 6' 3" | 210 lbs | - |
| Seto, Quiang | SP | MSL Pittsburgh Kingfishers | 17 | 08/30/2032 | Shanhwa | TPE | Right | Right | 6' 3" | 180 lbs | - |
| Shavlo, Yurik | SS | MSL Las Vegas Flamingos | 17 | 06/05/2032 | Balashikha | RUS | Left | Right | 6' 0" | 170 lbs | - |
| Shelton, Tony | 2B | MSL Buckhead Bowties | 19 | 09/26/2030 | Fernley | USA | Right | Right | 6' 0" | 170 lbs | - |
| Silva, Manny | 3B | MSL Montana Pandas | 18 | 09/06/2031 | Sosúa | DOM | Right | Right | 6' 4" | 200 lbs | - |
| Sims, Lee | C | MSL Thunder Bay Northern Lions BC | 18 | 04/27/2031 | North Reading | USA | Right | Right | 6' 1" | 200 lbs | - |
| Siraj, Saqr | C | MSL Pittsburgh Kingfishers | 17 | 04/01/2032 | Ramat Gan | ISR | Right | Right | 6' 1" | 180 lbs | - |
| Sizemore, Chip | RP | MSL Montana Pandas | 18 | 07/11/2031 | Tacoma | USA | Right | Right | 6' 2" | 190 lbs | - |
| Slot, Andy | CL | MSL Las Vegas Flamingos | 17 | 06/14/2032 | Oranjestad | ARU | Switch | Right | 6' 8" | 205 lbs | - |
| Smith, Lawrence | RF | Free Agent | 19 | 03/05/2030 | Bloomington | USA | Right | Left | 6' 2" | 200 lbs | - |
| Soto, Francisco | SP | MSL Kingston Township Knights | 16 | 04/03/2033 | Liberia | CRC | Right | Right | 6' 1" | 175 lbs | - |
| Stitt, Ron | C | MSL Las Vegas Flamingos | 18 | 09/15/2031 | Westminster | USA | Switch | Right | 6' 2" | 200 lbs | - |
| Stockill, Evan | RF | MSL Kingston Township Knights | 18 | 04/18/2031 | Port Antonio | JAM | Left | Left | 6' 3" | 195 lbs | - |
| Stone, Chris | SP | MSL Las Vegas Flamingos | 18 | 02/22/2031 | Cape Elizabeth | USA | Switch | Right | 6' 4" | 190 lbs | - |
| Styles, Sam | RF | MSL D.C. Divided | 18 | 06/07/2031 | Charlotte Amalie | VIR | Right | Right | 6' 2" | 185 lbs | - |
| Suzuki, Hokusai | 1B | MSL Panama City Piranhas | 17 | 03/06/2032 | Maruko | JPN | Right | Right | 6' 6" | 215 lbs | - |
| Swain, Mitch | LF | Free Agent | 19 | 05/21/2030 | Broken Arrow | USA | Left | Left | 6' 2" | 185 lbs | - |
| Sánchez, Ramón | SP | MSL Buckhead Bowties | 18 | 09/11/2031 | Puerto la Cruz | VEN | Left | Left | 6' 2" | 180 lbs | - |
| Sánchez, Sixto | SS | MSL Panama City Piranhas | 17 | 03/07/2032 | Bella Vista | PAN | Right | Right | 6' 1" | 170 lbs | - |
