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| Name | Pos | Team | Age | DOB | POB | Nationality | Bats | Throws | Height | Weight | Salary |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Sahagún, Júlio | 2B | New Orleans Voodoo | 25 | 11/23/2020 | El Estor | GUA | Right | Right | 6' 1" | 195 lbs | $2,000,000 |
| Sakurai, Rikyu | C | Nova Scotia Leviathan | 18 | 11/08/2027 | Gushikawa | JPN | Right | Right | 6' 1" | 200 lbs | - |
| Salazar, Zacarías | 3B | Cleveland Browns | 29 | 02/27/2016 | San Luis Potosí | MEX | Right | Right | 6' 1" | 205 lbs | $380,000 |
| Salcido, Carlos | RP | Detroit Elite | 35 | 09/23/2010 | El Cercado | DOM | Right | Right | 5' 10" | 165 lbs | $672,000 |
| Sang, Jung-jun | RF | Panama City Piranhas | 18 | 10/06/2027 | Uijeongbu | KOR | Left | Left | 6' 4" | 195 lbs | - |
| Santos, Juan | CF | Panama City Piranhas | 17 | 03/02/2028 | León | NCA | Right | Right | 6' 0" | 160 lbs | - |
| Santángel, Juan | LF | Nashville Outlaws | 26 | 07/15/2019 | Panama | PAN | Left | Left | 6' 1" | 185 lbs | $4,400,000 |
| Sarkies, Rod | 1B | Free Agent | 28 | 06/27/2017 | Canberra | AUS | Right | Right | 6' 3" | 220 lbs | - |
| Sato, Shingen | SS | Buckhead Bowties | 17 | 01/19/2028 | Gifu | JPN | Right | Right | 6' 2" | 170 lbs | - |
| Savinon, Pepe | LF | Buffalo White Walkers | 24 | 05/11/2021 | Culiacan | MEX | Right | Right | 6' 1" | 190 lbs | $280,000 |
| Schep, Andrej | SP | Vancouver Grey Wolves | 17 | 03/19/2028 | Cul De Sac | SIM | Left | Left | 6' 4" | 190 lbs | - |
| Schneider, Jared | 2B | Free Agent | 27 | 04/22/2018 | Tempe | USA | Left | Right | 6' 2" | 190 lbs | - |
| Schrattenthaler, David | SP | Thunder Bay Northern Lions BC | 26 | 02/02/2019 | Robbinsdale | USA | Switch | Right | 6' 0" | 185 lbs | $550,000 |
| Schreibvogel, Joe | 1B | Echo Park Lakers | 28 | 10/05/2017 | Garden City | USA | Left | Right | 6' 2" | 235 lbs | $3,550,000 |
| Scott, Mike | 2B | Detroit Elite | 26 | 12/29/2019 | San Antonio | USA | Left | Right | 6' 0" | 195 lbs | $280,000 |
| Serna, Aurelio | 3B | New Orleans Voodoo | 17 | 10/05/2028 | Santo Domingo | DOM | Right | Right | 6' 1" | 180 lbs | - |
| Seymour, Dan | SP | Las Vegas Flamingos | 25 | 03/04/2020 | Canton | USA | Right | Right | 6' 2" | 195 lbs | $490,000 |
| Shannon, Robert | 1B | Thunder Bay Northern Lions BC | 25 | 07/08/2020 | Paradise | USA | Left | Right | 6' 0" | 200 lbs | $280,000 |
| Shantsev, Jov | 1B | Montana Pandas | 17 | 07/23/2028 | Moscow | RUS | Right | Right | 6' 0" | 185 lbs | - |
| Shimizu, Yoshiki | CF | Buffalo White Walkers | 24 | 01/26/2021 | Ofunato | JPN | Right | Right | 6' 2" | 200 lbs | $280,000 |
| Sijne, Joost | RP | Free Agent | 17 | 07/08/2028 | Groot Piscadera | CUR | Left | Left | 6' 7" | 195 lbs | - |
| Simon, Carlos | RP | Nashville Outlaws | 33 | 11/13/2012 | Fresno | USA | Right | Right | 6' 3" | 205 lbs | $480,000 |
| Sinke, Marnix | 3B | Free Agent | 17 | 05/20/2028 | Princess Quarter | SIM | Right | Right | 6' 2" | 180 lbs | - |
| Skenandore, August | CF | Panama City Piranhas | 18 | 12/09/2027 | Diggle | ENG | Right | Right | 6' 1" | 175 lbs | - |
| Smith, Mark | SP | Buckhead Bowties | 26 | 11/06/2019 | Queens | USA | Right | Right | 6' 2" | 205 lbs | $280,000 |
| Song, Su-hyeon | SP | Vancouver Grey Wolves | 16 | 08/06/2029 | Daegu | KOR | Switch | Right | 6' 1" | 170 lbs | - |
| Sorondo, Julián | 2B | Las Vegas Flamingos | 21 | 12/05/2024 | Ciudad Bolívar | VEN | Left | Right | 6' 2" | 180 lbs | $280,000 |
| Souza, Jorge | SP | Thunder Bay Northern Lions BC | 25 | 09/01/2020 | Villa Vazquez | DOM | Right | Right | 6' 1" | 185 lbs | $13,125,000 |
| Spaan, Gerben | RF | Echo Park Lakers | 17 | 01/26/2028 | Cul De Sac | SIM | Left | Left | 6' 3" | 190 lbs | - |
| Starr, Jamie | 3B | Las Vegas Flamingos | 28 | 10/26/2017 | Carolina | PUR | Left | Right | 6' 3" | 215 lbs | $280,000 |
| Stenis, Andre | LF | Las Vegas Flamingos | 17 | 04/14/2028 | Rincon | ANT | Right | Right | 6' 5" | 195 lbs | - |
| Stevens, Marvin | SP | Thunder Bay Northern Lions BC | 27 | 11/25/2018 | Maynardville | USA | Right | Right | 6' 5" | 235 lbs | $280,000 |
| Strachota, Todd | RF | Thunder Bay Northern Lions BC | 29 | 11/03/2016 | St. Paul Park | USA | Left | Left | 6' 3" | 215 lbs | $280,000 |
| Sturges, Nigel | SS | Free Agent | 33 | 07/29/2012 | Avarua | COK | Right | Right | 6' 4" | 200 lbs | - |
| Stuterberg, Harry | RP | Las Vegas Flamingos | 35 | 10/06/2010 | New York | USA | Right | Right | 6' 2" | 210 lbs | $616,000 |
| Sutherland, Dan | SP | Buckhead Bowties | 16 | 07/15/2029 | Tamuning | GUM | Left | Right | 6' 2" | 175 lbs | - |
| Sweemey, Onson | RP | Montana Pandas | 36 | 05/09/2009 | Perris | USA | Left | Left | 6' 6" | 230 lbs | $280,000 |
| Szymanski, Aloysius | 1B | Buffalo White Walkers | 27 | 05/22/2018 | Milwaukee | USA | Right | Right | 6' 7" | 245 lbs | $280,000 |
| Sáenz, António | SS | Oakland Oaks | 17 | 03/27/2028 | Enriquillo | DOM | Left | Right | 6' 0" | 160 lbs | - |
| Sánchez, Leonardo | SP | Cleveland Browns | 26 | 07/13/2019 | North Decatur | USA | Left | Right | 6' 0" | 200 lbs | $280,000 |
| Sánchez, Orlando | SP | Detroit Elite | 17 | 03/30/2028 | Puerto Padre | CUB | Right | Right | 5' 10" | 160 lbs | - |
| Sánchez, Ramón | RP | Cleveland Browns | 28 | 03/09/2017 | Lake Los Angeles | USA | Right | Left | 5' 10" | 175 lbs | $280,000 |
