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| Name | Pos | Team | Age | DOB | POB | Nationality | Bats | Throws | Height | Weight | Salary |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Saelices, Paco | SS | Memphis Music | 18 | 03/14/2019 | San Salvador | SLV | Right | Right | 6' 2" | 175 lbs | - |
| Sahar, Anathapinda | SP | Memphis Music | 16 | 04/06/2021 | Shohratgarh | IND | Right | Left | 6' 2" | 175 lbs | - |
| Sánchez, Esteban | RP | Valley View Cougars | 21 | 12/15/2016 | Upata | VEN | Right | Right | 6' 4" | 195 lbs | - |
| Sanders, Paul | SS | Ogallala Octopi | 19 | 07/27/2018 | Hollandale | USA | Right | Right | 6' 2" | 180 lbs | - |
| Sandín, Mauro | SP | Crowley Cajuns | 19 | 11/21/2018 | Santiago | CRC | Right | Right | 6' 4" | 190 lbs | - |
| Santos, Jim | C | Ogallala Octopi | 18 | 01/15/2019 | Toledo | USA | Switch | Right | 6' 5" | 220 lbs | - |
| Santos, Pablo | SS | Surprise Shockers | 21 | 02/15/2016 | San Vicente | SLV | Right | Right | 6' 1" | 180 lbs | - |
| Sanz, Héctor | SP | Crowley Cajuns | 19 | 05/30/2018 | Constanza | DOM | Left | Left | 6' 2" | 180 lbs | - |
| Saromi, Sekien | RP | Free Agent | 17 | 07/20/2020 | Narashino | JPN | Right | Right | 6' 3" | 180 lbs | - |
| Sato, Momoru | CF | Crowley Cajuns | 19 | 04/21/2018 | Shizuoka | JPN | Right | Right | 6' 0" | 165 lbs | - |
| Sawyer, John | RP | Long Island Ducks | 20 | 06/10/2017 | Lehi | USA | Left | Left | 6' 2" | 175 lbs | - |
| Scott, Jerry | CF | Valley View Cougars | 19 | 01/25/2018 | Elizabethtown | USA | Right | Right | 6' 2" | 180 lbs | - |
| Secada, Diego Alejandro | 1B | Ladue Rams | 20 | 05/25/2017 | Desemparados | CRC | Switch | Right | 6' 5" | 215 lbs | - |
| Seki, Kojuro | C | Ogallala Octopi | 18 | 09/03/2019 | Naha | JPN | Right | Right | 6' 1" | 200 lbs | - |
| Shelley, Erwin | SP | Long Island Ducks | 19 | 08/25/2018 | Montreal | CAN | Right | Right | 6' 3" | 195 lbs | - |
| Shimizu, Hirokumi | RP | Ladue Rams | 21 | 10/26/2016 | Nagoya | JPN | Right | Right | 6' 3" | 190 lbs | - |
| Sierra, Juan | 2B | Long Island Ducks | 20 | 04/20/2017 | Rolling Hills Estates | USA | Right | Right | 6' 4" | 195 lbs | - |
| Silva, Armando | CF | Indiana Lead Sox | 21 | 03/24/2016 | Santo Domingo | DOM | Right | Right | 5' 11" | 175 lbs | - |
| Sin, Chang-weon | RP | Ogallala Octopi | 18 | 05/14/2019 | Daegu | KOR | Right | Right | 6' 2" | 185 lbs | - |
| Smith, Adam | SS | Hudsonville Flanderses | 22 | 12/24/2015 | Toledo | USA | Right | Right | 6' 0" | 185 lbs | - |
| Solís, Carlos | RP | Fort Knox Centennial | 20 | 06/19/2017 | Escazú | CRC | Left | Left | 6' 10" | 225 lbs | - |
| Sosa, Armando | SP | Indiana Lead Sox | 20 | 12/14/2017 | Santiago | CHI | Right | Right | 6' 0" | 165 lbs | - |
| Sousa, Jim | SP | Long Island Ducks | 19 | 04/07/2018 | Bordentown | USA | Right | Right | 6' 1" | 180 lbs | - |
| Sparks, John | SP | Ladue Rams | 21 | 01/29/2016 | McHenry | USA | Right | Right | 6' 2" | 180 lbs | - |
| Sparks, Stephen | 1B | Indiana Lead Sox | 21 | 02/07/2016 | Lackland AFB | USA | Right | Right | 6' 2" | 210 lbs | - |
| Starr, Jamie | 3B | Surprise Shockers | 20 | 10/26/2017 | Carolina | PUR | Left | Right | 6' 3" | 200 lbs | - |
| Starr, Joe | RP | Free Agent | 19 | 03/29/2018 | Lake Grove | USA | Right | Right | 6' 0" | 170 lbs | - |
| Stevens, Martin | CF | Crowley Cajuns | 20 | 01/05/2017 | Ft. Morgan | USA | Right | Right | 6' 1" | 180 lbs | - |
| Sweetapple, Rudolph | 2B | Free Agent | 21 | 10/22/2016 | Niagara Falls | CAN | Right | Right | 6' 0" | 180 lbs | - |
