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| Name | Pos | Team | Age | DOB | POB | Nationality | Bats | Throws | Height | Weight | Salary |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Salazar, Felipe | SP | Athletic Club KC | 19 | 08/10/2014 | Higüey | DOM | Switch | Right | 6' 0" | 170 lbs | - |
| Salazar, José | SP | Seattle Aviators | 17 | 06/05/2016 | Las Tunas | CUB | Right | Right | 6' 0" | 170 lbs | - |
| Salazar, Roberto | RF | Buckhead Bowties | 34 | 08/01/1999 | Pizarrete | DOM | Left | Left | 6' 2" | 205 lbs | $18,000,000 |
| Salazar, Zacarías | SS | Philadelphia 1776 BC | 17 | 02/27/2016 | San Luis Potosí | MEX | Right | Right | 6' 1" | 165 lbs | - |
| Salgado, Ramón | SP | Rocky Mountain Nuggets | 18 | 01/10/2015 | Villa Vazquez | DOM | Switch | Right | 6' 0" | 165 lbs | - |
| Sánchez, Bartolo | SP | Athletic Club KC | 18 | 04/09/2015 | Chiguayante | CHI | Switch | Left | 6' 2" | 175 lbs | - |
| Sánchez, Esteban | SP | Philadelphia 1776 BC | 17 | 12/15/2016 | Upata | VEN | Right | Right | 6' 3" | 185 lbs | - |
| Sánchez, Javier | 1B | New Jersey Fenix | 29 | 03/01/2004 | Villa Vazquez | DOM | Left | Left | 6' 4" | 245 lbs | $21,500,000 |
| Sánchez, Mario | RP | Panama City Piranhas | 21 | 08/14/2012 | Caracas | VEN | Right | Right | 6' 7" | 215 lbs | $280,000 |
| Sánchez, Roberto | C | Echo Park Lakers | 19 | 12/05/2014 | Santiago | DOM | Right | Right | 6' 0" | 185 lbs | - |
| Sánchez, Roberto | 1B | Panama City Piranhas | 30 | 11/17/2003 | San José de Ocoa | DOM | Left | Left | 6' 3" | 230 lbs | $3,000,000 |
| Sanders, Bernie | SP | Seattle Aviators | 30 | 02/18/2003 | Cleveland | USA | Left | Left | 6' 1" | 210 lbs | $820,000 |
| Sandoval, Eduardo | SP | Athletic Club KC | 22 | 04/01/2011 | Los Angeles | USA | Left | Left | 6' 3" | 190 lbs | - |
| Sandoval, Fernando | RF | Thunder Bay Northern Lions BC | 18 | 03/31/2015 | Soacha | COL | Left | Left | 6' 4" | 205 lbs | - |
| Santana, Luis | CF | Athletic Club KC | 17 | 04/17/2016 | La Romana | DOM | Right | Right | 6' 2" | 180 lbs | - |
| Santos, Manuel | C | Rocky Mountain Nuggets | 19 | 03/17/2014 | Guadalupe | CRC | Right | Right | 6' 4" | 210 lbs | - |
| Santos, Pedro | 2B | New Amsterdam Dutchmen | 34 | 07/27/1999 | Santo Domingo | DOM | Right | Right | 6' 3" | 235 lbs | $7,200,000 |
| Sanu, Narahiko | SP | Seattle Aviators | 16 | 07/30/2017 | Chiba | JPN | Right | Right | 6' 7" | 205 lbs | - |
| Sanu, Shiki | 3B | New Jersey Fenix | 26 | 05/29/2007 | Sapporo | JPN | Switch | Right | 6' 1" | 205 lbs | $1,766,666 |
| Saraf, Barsati | CF | Richardson City Thundercats | 17 | 04/28/2016 | Springs | RSA | Right | Right | 5' 11" | 165 lbs | - |
| Sashi, Arana | CF | Seattle Aviators | 26 | 10/20/2007 | Salimpur | IND | Left | Left | 6' 4" | 220 lbs | $280,000 |
| Schit, Puck | CF | New Amsterdam Dutchmen | 18 | 07/07/2015 | Willemstad | CUR | Left | Right | 6' 0" | 165 lbs | - |
| Schnatter, John | C | Free Agent | 32 | 04/19/2001 | Pomona | USA | Right | Right | 6' 0" | 225 lbs | - |
| Schuilenberg, Kasper | C | Thunder Bay Northern Lions BC | 25 | 09/14/2008 | Cole Bay | SIM | Right | Right | 6' 1" | 200 lbs | $280,000 |
| Schultz, Karl | RF | Free Agent | 37 | 09/01/1996 | Erie | USA | Right | Right | 5' 11" | 195 lbs | - |
| Sharp, Frank | LF | Brooklyn Dodgers | 30 | 07/04/2003 | Erie | USA | Left | Left | 6' 3" | 215 lbs | $550,000 |
| Shubhendu, Krtsna | SP | New Amsterdam Dutchmen | 18 | 06/10/2015 | Durban | RSA | Right | Right | 5' 11" | 170 lbs | - |
| Si, Yu-zeng | 3B | Buckhead Bowties | 23 | 06/17/2010 | Maanshan | CHN | Left | Right | 6' 2" | 200 lbs | $6,000,000 |
| Silva, Armando | CF | Richardson City Thundercats | 17 | 03/24/2016 | Santo Domingo | DOM | Right | Right | 5' 11" | 165 lbs | - |
| Silva, Ricardo | SP | Athletic Club KC | 21 | 03/18/2012 | Lima | PER | Right | Right | 5' 9" | 160 lbs | - |
| Silva, Roberto | RP | D.C. Divided | 29 | 08/11/2004 | Saginaw | USA | Right | Right | 6' 4" | 245 lbs | $4,784,000 |
| Slade, Wayne | SP | Athletic Club KC | 25 | 01/20/2008 | Markham | CAN | Right | Right | 6' 2" | 200 lbs | $3,808,000 |
| Slot, Sidney | SS | Chicago Gold Sox | 17 | 10/13/2016 | Willemstad | CUR | Right | Right | 6' 0" | 170 lbs | - |
| Smith, David | DH | Thunder Bay Northern Lions BC | 35 | 06/29/1998 | Hayward | USA | Left | Right | 6' 0" | 220 lbs | $850,000 |
| Solís, Pedro | C | Athletic Club KC | 29 | 10/06/2004 | Santo Domingo | DOM | Right | Right | 6' 1" | 230 lbs | $470,000 |
| Sorensen, Marty | SP | Thunder Bay Northern Lions BC | 16 | 03/05/2017 | Wanganui | NZL | Right | Right | 6' 3" | 190 lbs | - |
| Sosa, Ernesto | C | Wizarding Express | 18 | 08/29/2015 | Santo Domingo | DOM | Right | Right | 6' 1" | 195 lbs | - |
| Sosa, Fernando | SP | Nashville Outlaws | 19 | 07/20/2014 | Santo Domingo | DOM | Right | Left | 6' 0" | 170 lbs | - |
| Soto, Javier | SP | Brooklyn Dodgers | 17 | 12/14/2016 | Ciudad Bolívar | VEN | Left | Right | 6' 4" | 190 lbs | - |
| Soto, Roberto | 2B | Brooklyn Dodgers | 30 | 11/30/2003 | Anselmo Llorente | CRC | Left | Right | 6' 0" | 200 lbs | $280,000 |
| Sperber, Murray | CF | Panama City Piranhas | 22 | 04/09/2011 | Battle Creek | USA | Left | Left | 6' 0" | 190 lbs | $280,000 |
| Spurgeon, Morlack | RP | New Amsterdam Dutchmen | 28 | 01/24/2005 | Lakewood | USA | Left | Left | 6' 7" | 235 lbs | $430,000 |
| Strickland, Mike | 3B | Panama City Piranhas | 28 | 02/26/2005 | New York | USA | Right | Right | 6' 0" | 210 lbs | $4,000,000 |
| Suárez, Reynaldo | C | Thunder Bay Northern Lions BC | 17 | 07/15/2016 | El Estor | GUA | Right | Right | 6' 0" | 190 lbs | - |
| Suárez, Robinson | SP | Panama City Piranhas | 28 | 01/02/2005 | Villa Elisa | DOM | Right | Right | 5' 10" | 185 lbs | $1,500,000 |
| Sugahara, Shotaro | SP | Brooklyn Dodgers | 29 | 05/25/2004 | Nishinomiya | JPN | Right | Right | 5' 11" | 190 lbs | $280,000 |
