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| Name | Pos | Team | Age | DOB | POB | Nationality | Bats | Throws | Height | Weight | Salary |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Sagástegui, Carlos | SP | Wizarding Express | 17 | 10/07/2007 | Rincón | DOM | Left | Left | 6' 2" | 170 lbs | - |
| Saikawa, Toshiro | RP | Free Agent | 30 | 06/29/1994 | Hiroshima | JPN | Left | Right | 5' 8" | 190 lbs | - |
| Salaedo, Pancho | 2B | Montana Pandas | 25 | 12/19/1999 | Santo Domingo | DOM | Right | Right | 6' 3" | 195 lbs | $448,000 |
| Salazar, Claudio | SP | Panama City Piranhas | 19 | 09/25/2005 | San Pedro de Macorís | DOM | Right | Right | 6' 8" | 215 lbs | - |
| Salazar, Jesús | SP | D.C. Divided | 20 | 10/09/2004 | Santo Domingo | DOM | Left | Left | 6' 1" | 180 lbs | - |
| Salazar, Martín | SP | Austin Rangers | 18 | 05/29/2006 | Santiago | DOM | Right | Left | 6' 1" | 170 lbs | - |
| Samson, Addie | SP | Brooklyn Dodgers | 24 | 03/01/2000 | Westerveld | NED | Left | Left | 6' 1" | 200 lbs | $470,000 |
| Sánchez, Alejandro | 3B | Philadelphia 1776 BC | 19 | 12/14/2005 | Higüey | DOM | Right | Right | 6' 2" | 190 lbs | - |
| Sánchez, Carlos | SP | Philadelphia 1776 BC | 23 | 06/04/2001 | Maracaibo | VEN | Left | Left | 6' 2" | 190 lbs | $4,266,000 |
| Sánchez, Enrique | LF | Austin Rangers | 22 | 10/29/2002 | Charallave | VEN | Left | Left | 6' 6" | 205 lbs | $280,000 |
| Sánchez, Francisco | SP | Capital District Red Knights | 19 | 07/25/2005 | Ciudad Guayana | VEN | Left | Left | 5' 8" | 160 lbs | - |
| Sánchez, Javier | 1B | Rocky Mountain Nuggets | 20 | 03/01/2004 | Villa Vazquez | DOM | Left | Left | 6' 4" | 215 lbs | $280,000 |
| Sánchez, Jesús | SP | Montana Pandas | 18 | 05/25/2006 | Santiago | DOM | Right | Right | 6' 1" | 175 lbs | - |
| Sánchez, Juan | C | Rocky Mountain Nuggets | 34 | 11/19/1990 | Valencia | VEN | Switch | Right | 6' 3" | 245 lbs | $3,000,000 |
| Sánchez, Luis | SP | Kingston Township Legion | 17 | 07/19/2007 | Ciudad Guayana | VEN | Right | Right | 5' 10" | 155 lbs | - |
| Sánchez, Manuel | SP | Panama City Piranhas | 19 | 06/21/2005 | Maracaibo | VEN | Right | Right | 6' 1" | 190 lbs | - |
| Sánchez, Raúl | SP | Brooklyn Dodgers | 16 | 10/20/2008 | Bajos de Haina | DOM | Right | Right | 5' 11" | 165 lbs | - |
| Sánchez, Reynaldo | SP | Kingston Township Legion | 24 | 08/06/2000 | Ocumare del Tuy | VEN | Left | Left | 6' 3" | 185 lbs | $280,000 |
| Sánchez, Wilson | 3B | Austin Rangers | 17 | 04/25/2007 | Las Salinas | DOM | Right | Right | 5' 10" | 170 lbs | - |
| Sandoval, Culley | RP | Las Vegas Flamingos | 27 | 07/22/1997 | Urbana | USA | Right | Right | 6' 0" | 190 lbs | $5,220,000 |
| Sandoval, José | RP | Philadelphia 1776 BC | 25 | 04/05/1999 | Santo Domingo | DOM | Left | Left | 6' 8" | 215 lbs | $280,000 |
| Sandoval, Ricardo | SS | D.C. Divided | 18 | 09/03/2006 | Maracaibo | VEN | Right | Right | 6' 0" | 170 lbs | - |
| Sandry, Shaun | SP | Las Vegas Flamingos | 16 | 07/31/2008 | Orange Walk | BLZ | Right | Right | 6' 7" | 195 lbs | - |
| Santiago, Alejandro | 1B | Hartford Whalers | 19 | 05/07/2005 | Peralta | DOM | Right | Right | 6' 5" | 215 lbs | - |
| Santos, Juan Carlos | LF | Thunder Bay Northern Lions BC | 19 | 04/10/2005 | Santiago | DOM | Switch | Left | 6' 1" | 190 lbs | - |
| Sasaki, Ryobe | C | Philadelphia 1776 BC | 17 | 10/29/2007 | Nagoya | JPN | Right | Right | 6' 4" | 205 lbs | - |
| Sato, Suezo | RP | Chicago Hawks | 35 | 04/09/1989 | Tajimi | JPN | Right | Right | 6' 0" | 220 lbs | $445,000 |
| Satyavrat, Manoo | CF | Philadelphia 1776 BC | 19 | 08/15/2005 | Pehlad Pur Bangar | IND | Left | Left | 6' 1" | 175 lbs | - |
| Schneider, Jeff | RP | Philadelphia 1776 BC | 24 | 06/03/2000 | Cincinnati | USA | Right | Left | 6' 3" | 200 lbs | $280,000 |
| Scott, Jim | 3B | Montana Pandas | 24 | 09/14/2000 | Alexandria | USA | Right | Right | 6' 0" | 190 lbs | $280,000 |
| Seah, Jin-song | CF | Las Vegas Flamingos | 17 | 03/28/2007 | Taichung | TPE | Left | Left | 6' 2" | 175 lbs | - |
| Shaffer, Cole | 1B | Wizarding Express | 27 | 07/14/1997 | New York | USA | Right | Right | 6' 0" | 205 lbs | $9,500,000 |
| Shannon, Wes | CF | Rocky Mountain Nuggets | 23 | 07/03/2001 | Aurora | USA | Right | Right | 6' 2" | 190 lbs | $280,000 |
| Shaw, Theodore | RF | Montana Pandas | 34 | 07/06/1990 | Charlotte | USA | Left | Left | 6' 1" | 215 lbs | $430,000 |
| Shelton, Jake | LF | Las Vegas Flamingos | 34 | 06/27/1990 | Lake Charles | USA | Left | Right | 6' 5" | 240 lbs | $644,000 |
| Sheppard, Willem | RF | Montana Pandas | 19 | 09/19/2005 | Taupo | NZL | Left | Left | 6' 1" | 175 lbs | - |
| Shimada, Mito | SP | Montana Pandas | 18 | 06/28/2006 | Yokohama | JPN | Right | Right | 6' 3" | 185 lbs | - |
| Silva, Carlos | SS | Wizarding Express | 18 | 08/13/2006 | Bonao | DOM | Right | Right | 6' 0" | 170 lbs | - |
| Silva, Francisco | SP | Wizarding Express | 17 | 09/06/2007 | San José | CRC | Right | Right | 6' 6" | 195 lbs | - |
| Simmons, Donald | RP | Free Agent | 33 | 09/04/1991 | Mason City | USA | Right | Right | 6' 0" | 210 lbs | - |
| Simonse, Bartho | 3B | Kingston Township Legion | 16 | 03/28/2008 | Rijnsburg | NED | Right | Right | 6' 2" | 190 lbs | - |
| Slater, Arnold | SP | Hartford Whalers | 18 | 03/20/2006 | Melbourne | AUS | Right | Right | 6' 0" | 175 lbs | - |
| Smith, Chris | 1B | Free Agent | 36 | 05/02/1988 | Little Elm | USA | Right | Right | 6' 1" | 260 lbs | - |
| Smith, Joe | C | Philadelphia 1776 BC | 27 | 07/25/1997 | New York | USA | Right | Right | 5' 11" | 195 lbs | $500,000 |
| Smith, Paul | 3B | Rocky Mountain Nuggets | 31 | 02/04/1993 | Wrightsboro | USA | Right | Right | 6' 2" | 210 lbs | $550,000 |
| Snow, Myron | RP | Seattle Aviators | 38 | 07/15/1986 | North Weeki Wachee | USA | Right | Right | 6' 0" | 230 lbs | $4,000,000 |
| Solís, Jesús | RP | Free Agent | 19 | 03/02/2005 | Santo Domingo | DOM | Left | Left | 5' 10" | 155 lbs | - |
| Sotelo, Leonardo | C | Kingston Township Legion | 18 | 02/08/2006 | Altamira | DOM | Right | Right | 6' 0" | 190 lbs | - |
| Soto, Manny | SS | Rocky Mountain Nuggets | 19 | 02/04/2005 | La Vega | DOM | Right | Right | 6' 0" | 170 lbs | - |
| Spargo, Mick | 1B | Las Vegas Flamingos | 16 | 09/16/2008 | Ballarat | AUS | Right | Right | 6' 3" | 190 lbs | - |
| Spear, Keith | RF | Hartford Whalers | 34 | 07/19/1990 | Abbeville | USA | Left | Left | 5' 11" | 195 lbs | $280,000 |
| Spee, Sven | SS | Thunder Bay Northern Lions BC | 20 | 10/23/2004 | Utrecht | NED | Switch | Right | 6' 0" | 180 lbs | - |
| Spencer, Jeremiah | SS | Chicago Hawks | 28 | 02/18/1996 | Monroe | USA | Left | Right | 6' 3" | 220 lbs | $450,000 |
| Spicer, Simon | SP | Wizarding Express | 17 | 09/21/2007 | Hastings | NZL | Left | Right | 6' 7" | 200 lbs | - |
| Stafford, Josh | 3B | Brooklyn Dodgers | 25 | 02/09/1999 | Splendora | USA | Right | Right | 6' 1" | 185 lbs | $280,000 |
| Stanley, Tommy | CF | Hartford Whalers | 27 | 08/30/1997 | Stanton | USA | Right | Right | 5' 11" | 195 lbs | $280,000 |
| Steel, Isaac | SP | Capital District Red Knights | 17 | 06/22/2007 | Freeport | BAH | Right | Right | 5' 11" | 165 lbs | - |
| Steele, Chuck | SP | Free Agent | 29 | 08/09/1995 | Independence | USA | Left | Right | 6' 2" | 220 lbs | - |
| Stevens, Dale | RP | Hartford Whalers | 30 | 11/20/1994 | Anna | USA | Left | Left | 6' 3" | 215 lbs | $550,000 |
| Stroo, Nees | SP | Austin Rangers | 16 | 09/23/2008 | Oranjestad | ARU | Left | Left | 6' 3" | 180 lbs | - |
| Sullivan, Lester | SP | Austin Rangers | 27 | 01/21/1997 | North Richland Hills | USA | Right | Right | 6' 0" | 190 lbs | $280,000 |
| Sullivan, Woody | CL | Philadelphia 1776 BC | 27 | 09/02/1997 | Plymouth Township | USA | Left | Left | 6' 1" | 215 lbs | $450,000 |
| Sun, Decheng | RP | Austin Rangers | 30 | 09/25/1994 | Taichung | TPE | Right | Right | 6' 1" | 210 lbs | $4,600,000 |
| Sylvester, Terry | LF | Las Vegas Flamingos | 31 | 10/01/1993 | Montgomery Township | USA | Right | Right | 6' 0" | 205 lbs | $3,800,000 |
