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| Name | Pos | Team | Age | DOB | POB | Nationality | Bats | Throws | Height | Weight | Salary |
|---|---|---|---|---|---|---|---|---|---|---|---|
| O'Connor, Leonard | 1B | Brooklyn Dodgers | 29 | 11/04/1995 | Altavista | USA | Switch | Right | 6' 0" | 220 lbs | $13,150,000 |
| Ocegueda, Ramón | SP | Philadelphia 1776 BC | 18 | 09/05/2006 | Salamanca | MEX | Right | Right | 6' 2" | 180 lbs | - |
| Oike, Akihiko | 1B | Chicago Hawks | 33 | 02/01/1991 | Tokyo | JPN | Right | Right | 6' 2" | 230 lbs | $950,000 |
| Oliva, Luis | C | Hartford Whalers | 18 | 09/16/2006 | Santo Domingo | DOM | Right | Right | 6' 0" | 185 lbs | - |
| Oliveira, Roberto | SP | Philadelphia 1776 BC | 19 | 11/25/2005 | Santo Domingo | DOM | Right | Right | 6' 4" | 195 lbs | - |
| Olivo, Esteban | 2B | Panama City Piranhas | 19 | 06/16/2005 | Santo Domingo | DOM | Right | Right | 5' 11" | 170 lbs | - |
| Olsson, Emil | SP | Montana Pandas | 18 | 08/15/2006 | Kovel | UKR | Right | Right | 6' 2" | 175 lbs | - |
| Omarov, Azamat | SP | Las Vegas Flamingos | 17 | 02/02/2007 | Astana | KAZ | Right | Right | 6' 0" | 165 lbs | - |
| Omikado, Doppo | RP | Philadelphia 1776 BC | 18 | 09/23/2006 | Konan | JPN | Left | Left | 6' 2" | 180 lbs | - |
| Ong, Tzu-hsia | SP | Chicago Hawks | 18 | 02/10/2006 | Qingdao | CHN | Left | Left | 6' 5" | 200 lbs | - |
| Opalka, Milan | SP | Seattle Aviators | 17 | 11/15/2007 | Amsterdam | NED | Right | Right | 6' 0" | 175 lbs | - |
| Orozco, Jesús | 1B | Philadelphia 1776 BC | 26 | 03/11/1998 | Barinas | VEN | Right | Right | 6' 3" | 215 lbs | $5,180,000 |
| Ortega, Carlos | 1B | Wizarding Express | 31 | 12/14/1993 | Havana | CUB | Right | Right | 5' 11" | 215 lbs | $1,020,000 |
| Ortega, Pedro | SS | Seattle Aviators | 18 | 03/20/2006 | Matagalpa | NCA | Switch | Right | 6' 4" | 185 lbs | - |
| Ortíz, Carlos | SP | Rocky Mountain Nuggets | 18 | 08/13/2006 | Santo Domingo | DOM | Right | Right | 6' 2" | 180 lbs | - |
| Ortíz, Joaquín | RP | Montana Pandas | 20 | 05/19/2004 | Santo Domingo | DOM | Right | Right | 6' 2" | 185 lbs | - |
| Ortíz, Jorge | SS | Seattle Aviators | 18 | 08/20/2006 | San Francisco de Macorís | DOM | Left | Right | 6' 2" | 175 lbs | - |
| Ortíz, José | C | Hartford Whalers | 20 | 11/16/2004 | Mexico City | MEX | Right | Right | 5' 10" | 175 lbs | - |
| Ortíz, Pancho | SP | Wizarding Express | 20 | 06/26/2004 | El Seibo | DOM | Right | Right | 6' 1" | 185 lbs | - |
| Ortíz, Reynaldo | SP | Rocky Mountain Nuggets | 24 | 09/02/2000 | Caracas | VEN | Right | Right | 5' 11" | 175 lbs | $280,000 |
| Otomo, Yajirobei | SP | Seattle Aviators | 19 | 05/27/2005 | Unknown | JPN | Left | Left | 6' 8" | 210 lbs | - |
| Ough, Peter | SS | Hartford Whalers | 17 | 07/17/2007 | Melbourne | AUS | Left | Right | 6' 1" | 180 lbs | - |
