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| Name | Pos | Team | Age | DOB | POB | Nationality | Bats | Throws | Height | Weight | Salary |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Salinas, Sergio | RP | MSL St. Louis Coeur | 17 | 02/06/2039 | Caracas | VEN | Right | Right | 5' 11" | 165 lbs | - |
| Sandoval, Octávio | 3B | MSL Athletic Club KC U-18 | 19 | 07/14/2037 | Chiclayo | PER | Right | Right | 6' 2" | 190 lbs | - |
| Santana, Gustavo | C | MSL Athletic Club KC U-18 | 19 | 09/05/2037 | Puerto Plata | DOM | Right | Right | 6' 1" | 180 lbs | - |
| Sasaki, Hideaki | SP | MSL Athletic Club KC U-18 | 18 | 06/01/2038 | Asahikawa | JPN | Right | Right | 6' 4" | 190 lbs | - |
| Sato, Hirokichi | SS | MSL D.C. Divided | 18 | 11/22/2038 | Rumoi | JPN | Right | Right | 6' 3" | 180 lbs | - |
| Sayers, Spencer | SP | MSL Seattle Rocketeers | 17 | 03/09/2039 | Burgh le Marsh | ENG | Left | Left | 6' 4" | 180 lbs | - |
| Sheppard, Michael | RP | MSL Vancouver Grey Wolves | 18 | 01/26/2038 | Douglasville | USA | Right | Right | 6' 0" | 175 lbs | - |
| Silva, Domingo | SP | MSL Long Island Lighthouse | 18 | 05/05/2038 | Santo Domingo | DOM | Switch | Right | 6' 1" | 175 lbs | - |
| Silva, Raúl | C | MSL Seattle Rocketeers | 18 | 06/27/2038 | Loreto | MEX | Right | Right | 6' 2" | 180 lbs | - |
| Simonse, Dirkjan | RP | MSL Seattle Rocketeers | 17 | 10/17/2039 | Cul De Sac | SIM | Right | Right | 6' 6" | 200 lbs | - |
| Smerdon, Paul | CL | MSL St. Louis Coeur | 19 | 08/26/2037 | Willemstad | CUR | Right | Right | 6' 2" | 180 lbs | - |
| Solleveld, Ulbert | SS | MSL Boston Patriots | 19 | 11/28/2037 | Willemstad | CUR | Right | Right | 6' 2" | 190 lbs | - |
| Sosa, Gustavo | RP | Free Agent | 19 | 07/24/2037 | Santiago | DOM | Right | Right | 6' 3" | 190 lbs | - |
| Soto, Juan | SP | MSL Long Island Lighthouse | 18 | 03/20/2038 | Mendoza | ARG | Right | Left | 6' 4" | 185 lbs | - |
| Stanley, Dave | 3B | Free Agent | 23 | 12/13/2033 | Monroeville | USA | Right | Right | 6' 3" | 210 lbs | - |
| Suárez, Armando | RF | MSL Long Island Lighthouse | 19 | 06/04/2037 | Guantanamo | CUB | Left | Left | 6' 5" | 200 lbs | - |
| Suárez, Manuel | RP | MSL St. Louis Coeur | 19 | 10/01/2037 | Yaritagua | VEN | Right | Right | 6' 0" | 170 lbs | - |
| Sánchez, Francisco | SS | MSL Vancouver Grey Wolves | 17 | 03/30/2039 | Badalona | ESP | Right | Right | 6' 2" | 175 lbs | - |
| Sánchez, Jorge | 3B | MSL D.C. Divided | 17 | 04/10/2039 | Santo Domingo | DOM | Left | Right | 6' 0" | 165 lbs | - |
| Sánchez, Jorge | 2B | MSL New Orleans Voodoo | 17 | 11/20/2039 | Sevilla | ESP | Right | Right | 6' 1" | 165 lbs | - |
