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| Name | Pos | Team | Age | DOB | POB | Nationality | Bats | Throws | Height | Weight | Salary |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Sakata, Minoru | RP | Port Huron Blitzkrieg | 26 | 08/18/2030 | Boston | USA | Right | Right | 6' 2" | 200 lbs | - |
| Salas, Gabriel | SP | Ft. Myers Marlins | 27 | 11/18/2029 | Maracaibo | VEN | Left | Left | 6' 0" | 190 lbs | - |
| Salas, Jorge | RP | Alaskan Humpbacks | 26 | 03/23/2030 | Santo Domingo | DOM | Left | Left | 6' 1" | 200 lbs | - |
| Sanders, Wallace | SS | Alaskan Humpbacks | 33 | 02/17/2023 | Grove City | USA | Right | Right | 6' 1" | 200 lbs | - |
| Sandoval, Luis | 3B | Ft. Myers Marlins | 25 | 09/12/2031 | Guantanamo | CUB | Right | Right | 6' 3" | 200 lbs | - |
| Santingo, Ángel | SP | Monongahela Monsters | 30 | 01/15/2026 | Santo Domingo | DOM | Right | Right | 5' 11" | 200 lbs | $750,000 |
| Santos, José | 2B | Sioux Falls Red Pandas | 32 | 01/01/2024 | Santo Domingo | DOM | Switch | Right | 6' 1" | 200 lbs | $800,000 |
| Sanu, Kensaku | RP | Port Huron Blitzkrieg | 30 | 08/12/2026 | Fujisawa | JPN | Right | Left | 6' 4" | 200 lbs | $280,000 |
| Sappington, Atticus | 2B | Tortolita Drummers | 24 | 08/27/2032 | Brooklyn | USA | Right | Right | 5' 10" | 185 lbs | - |
| Scarlett, Cliff | SP | Tortolita Drummers | 28 | 03/23/2028 | Saskatoon | CAN | Right | Right | 6' 3" | 200 lbs | $280,000 |
| Schaller, Ari | RP | Free Agent | 35 | 04/20/2021 | Eggendorf | AUT | Right | Right | 6' 1" | 200 lbs | - |
| Schmidt, Pat | 1B | Ft. Myers Marlins | 26 | 02/13/2030 | Medford | USA | Right | Right | 6' 2" | 210 lbs | - |
| Schroeder, Carl | RF | Free Agent | 25 | 01/17/2031 | Chapmanville | USA | Right | Right | 6' 0" | 195 lbs | - |
| Schwarzacher, Max | RP | Sacramento Redlegs | 24 | 04/20/2032 | Stanford | USA | Right | Left | 6' 3" | 200 lbs | - |
| Scott, Milton | LF | Sacramento Redlegs | 26 | 12/01/2030 | Corona | USA | Left | Right | 6' 6" | 210 lbs | - |
| Scroby, Tom | 2B | Port Huron Blitzkrieg | 33 | 10/26/2023 | Danielson | USA | Right | Right | 6' 0" | 200 lbs | - |
| Segura, Domingo | 1B | Tortolita Drummers | 25 | 01/13/2031 | Los Angeles | USA | Left | Left | 6' 2" | 205 lbs | - |
| Seppänen, Seppo | SP | Kansas Rainbeaus | 25 | 12/09/2031 | Szentes | HUN | Right | Right | 6' 1" | 185 lbs | - |
| Shaffer, Nelson | RP | Sioux Falls Red Pandas | 27 | 01/18/2029 | Meridian | USA | Switch | Right | 6' 3" | 200 lbs | $280,000 |
| Shantsev, Jov | 1B | Monongahela Monsters | 28 | 07/23/2028 | Moscow | RUS | Right | Right | 6' 0" | 200 lbs | - |
| Sherman, Mike | 2B | Port Huron Blitzkrieg | 32 | 06/12/2024 | Colorado Springs | USA | Switch | Right | 6' 1" | 195 lbs | - |
| Silva, José | 3B | Ft. Myers Marlins | 30 | 06/12/2026 | Enriquillo | DOM | Left | Right | 6' 0" | 195 lbs | - |
| Silva, Raúl | 1B | Norfolk Pajaritos | 24 | 03/26/2032 | Constanza | DOM | Left | Left | 6' 7" | 205 lbs | - |
| Silver, Albert | SP | Free Agent | 28 | 07/15/2028 | Austin | USA | Left | Right | 6' 2" | 200 lbs | - |
| Sim, Pyeong-ho | 2B | Ft. Myers Marlins | 30 | 03/25/2026 | Seongnam | KOR | Switch | Right | 6' 4" | 200 lbs | - |
| Simha, Balanatha | 3B | Port Huron Blitzkrieg | 25 | 02/03/2031 | Pune Cantonment | IND | Right | Right | 6' 3" | 200 lbs | $280,000 |
| Simpson, John | 3B | Alaskan Humpbacks | 35 | 11/02/2021 | Memphis | USA | Right | Right | 5' 11" | 195 lbs | - |
| Small, Chris | SP | Norfolk Pajaritos | 31 | 07/27/2025 | Cincinnati | USA | Left | Right | 6' 2" | 200 lbs | - |
| Smith, Craig | SP | Sunset District Fog | 26 | 09/09/2030 | San Francisco | USA | Left | Right | 6' 2" | 200 lbs | $280,000 |
| Solomonidis, Panagiotis | CF | Alaskan Humpbacks | 24 | 06/27/2032 | Thessaloníki | GRE | Left | Left | 6' 4" | 200 lbs | - |
| Spencer, James | RP | Port Huron Blitzkrieg | 32 | 12/26/2024 | Camden | USA | Right | Right | 6' 0" | 200 lbs | $700,000 |
| Spilsbury, Zachary | C | Free Agent | 29 | 07/27/2027 | London | ENG | Right | Right | 6' 1" | 205 lbs | - |
| Stensel, Cenek | RP | Kansas Rainbeaus | 29 | 09/03/2027 | Nachod | CZE | Right | Right | 6' 3" | 200 lbs | - |
| Strickland, Gregory | SS | Kansas Rainbeaus | 27 | 07/05/2029 | Charlotte | USA | Right | Right | 6' 2" | 200 lbs | - |
| Sánchez, Eduardo | SP | Kansas Rainbeaus | 25 | 06/30/2031 | Santo Tomas | SLV | Switch | Right | 5' 10" | 185 lbs | - |
| Sánchez, José | 2B | Tortolita Drummers | 26 | 10/18/2030 | Lagunillas | VEN | Right | Right | 6' 3" | 200 lbs | - |
| Sánchez, Roberto | RP | Sacramento Redlegs | 27 | 07/06/2029 | Santo Domingo | DOM | Right | Right | 6' 6" | 200 lbs | - |
