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| Name | Pos | Team | Age | DOB | POB | Nationality | Bats | Throws | Height | Weight | Salary |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Saelices, Ángel | 3B | Santa Catalina Condor | 36 | 02/10/2020 | Santo Domingo | DOM | Right | Right | 5' 9" | 200 lbs | $9,500,000 |
| Saikawa, Matsusuke | 1B | Dayton Dirty Reds | 31 | 06/26/2025 | Chofu | JPN | Left | Left | 6' 4" | 200 lbs | $3,800,000 |
| Salazar, Alonso | SP | Dayton Dirty Reds | 29 | 01/31/2027 | Holguín | CUB | Right | Right | 6' 1" | 205 lbs | $1,000,000 |
| Salazar, Félix | RP | Free Agent | 17 | 07/01/2039 | Lima | PER | Left | Left | 6' 4" | 180 lbs | - |
| Salinas, Fernando | SS | Free Agent | 16 | 09/10/2040 | Los Santos | PAN | Right | Right | 6' 1" | 160 lbs | - |
| Sam, Jong-min | RP | Free Agent | 20 | 07/18/2036 | Changwon | KOR | Right | Right | 6' 1" | 175 lbs | - |
| San Pedro, Tony | C | Northern Virginia Rainbow Mermaids | 35 | 04/29/2021 | San Pedro Sula | HON | Left | Right | 6' 0" | 200 lbs | $2,580,000 |
| Sanderson, Alan | RP | Echo Park Lakers | 30 | 10/31/2026 | Park Ridge | USA | Left | Right | 5' 10" | 200 lbs | $460,000 |
| Sandison, Len | CF | Las Vegas Flamingos | 34 | 10/13/2022 | Marion | USA | Left | Left | 6' 0" | 200 lbs | $1,100,000 |
| Sandoval, Javier | 3B | Buckhead Bowties | 16 | 11/25/2040 | Santo Domingo | DOM | Left | Right | 6' 2" | 185 lbs | - |
| Santos, Arturo | SP | Toledo Stingers | 16 | 01/26/2040 | Camoapa | NCA | Switch | Left | 6' 1" | 165 lbs | - |
| Santos, Jorge | RP | Thunder Bay Northern Lions BC | 29 | 06/23/2027 | San Miguel | CRC | Left | Left | 6' 3" | 200 lbs | $280,000 |
| Saracho, Jaicus | 1B | Kingston Ponies | 32 | 02/28/2024 | Malasila | PHI | Right | Right | 6' 2" | 200 lbs | $800,000 |
| Sardaneta, Salvador | CF | Free Agent | 20 | 05/19/2036 | Warwick | USA | Right | Right | 6' 1" | 185 lbs | - |
| Sato, Yamato | 1B | Echo Park Lakers | 35 | 10/01/2021 | Tokyo | JPN | Left | Left | 6' 0" | 200 lbs | $8,000,000 |
| Saunders, Leonard | CF | Thunder Bay Northern Lions BC | 34 | 11/06/2022 | New York | USA | Right | Right | 6' 2" | 205 lbs | $1,976,000 |
| Schmitt, Brian | LF | Free Agent | 24 | 10/21/2032 | Country Club Estates | USA | Right | Right | 6' 2" | 210 lbs | - |
| Schoof, Johan | C | Colorado Billy Goats | 17 | 06/23/2039 | Sint Nicolas | ARU | Right | Right | 6' 0" | 175 lbs | - |
| Seow, Ming | CF | Northern Virginia Rainbow Mermaids | 16 | 04/07/2040 | Yuanping | CHN | Right | Right | 5' 11" | 160 lbs | - |
| Shoemaker, Andrew | RP | Thunder Bay Northern Lions BC | 31 | 08/01/2025 | West Long Branch | USA | Right | Right | 6' 0" | 200 lbs | $280,000 |
| Silver, Duke | SP | Northern Virginia Rainbow Mermaids | 24 | 07/20/2032 | San Francisco | USA | Left | Right | 5' 10" | 185 lbs | $280,000 |
| Simon, Claude | RP | Kingston Ponies | 29 | 12/18/2027 | Burnaby | CAN | Right | Right | 6' 4" | 200 lbs | $280,000 |
| Sizemore, Chip | RP | Dayton Dirty Reds | 25 | 07/11/2031 | Tacoma | USA | Right | Right | 6' 2" | 200 lbs | $280,000 |
| Smith, Andrew | 1B | Toledo Stingers | 28 | 07/12/2028 | New River | USA | Left | Left | 6' 6" | 200 lbs | $280,000 |
| Smith, Brandon | C | Kingston Ponies | 31 | 04/21/2025 | Pflugerville | USA | Right | Right | 6' 1" | 200 lbs | $280,000 |
| Smith, Jim | SP | Toledo Stingers | 26 | 05/11/2030 | Toledo | USA | Switch | Right | 6' 2" | 195 lbs | $440,000 |
| Smith, Lance | 2B | Northern Virginia Rainbow Mermaids | 27 | 06/23/2029 | Daly City | USA | Left | Right | 6' 0" | 200 lbs | $280,000 |
| Sorondo, Julián | 3B | Las Vegas Flamingos | 32 | 12/05/2024 | Ciudad Bolívar | VEN | Left | Right | 6' 2" | 200 lbs | $14,500,000 |
| Sosa, Claudio | 2B | Thunder Bay Northern Lions BC | 27 | 10/21/2029 | Santiago | DOM | Left | Right | 6' 1" | 200 lbs | $650,000 |
| Sotelo, Gerardo | SS | Dayton Dirty Reds | 26 | 12/18/2030 | Chichicastenango | GUA | Left | Right | 5' 11" | 190 lbs | $410,000 |
| Soto, Emílio | 2B | Free Agent | 32 | 10/22/2024 | Cajamarca | PER | Right | Right | 6' 0" | 200 lbs | - |
| Spee, Roel | LF | Free Agent | 16 | 07/10/2040 | Willemstad | CUR | Right | Left | 6' 1" | 185 lbs | - |
| Spilsbury, Bryan | C | Charleston Battery | 28 | 11/25/2028 | South Ockendon | ENG | Switch | Right | 6' 3" | 200 lbs | $5,500,000 |
| Starks, Conor | SP | Santa Catalina Condor | 32 | 03/06/2024 | Lévis | CAN | Switch | Right | 5' 9" | 200 lbs | $18,400,000 |
| Sterk, Henri | 2B | Northern Virginia Rainbow Mermaids | 17 | 12/05/2039 | Willemstad | CUR | Right | Right | 6' 0" | 170 lbs | - |
| Stinson, Hunter | SP | Charleston Battery | 27 | 10/28/2029 | Brooklyn | USA | Left | Left | 6' 2" | 200 lbs | $900,000 |
| Stirzacre, Everton | RP | Nova Scotia Leviathan | 35 | 06/14/2021 | Somersham | ENG | Left | Left | 6' 4" | 200 lbs | $580,000 |
| Sullivan, Ron | C | Free Agent | 24 | 02/21/2032 | Denver | USA | Left | Right | 5' 11" | 195 lbs | - |
| Suzuki, Kyushichi | 2B | Toledo Stingers | 16 | 06/05/2040 | Kawajima | JPN | Right | Right | 6' 3" | 185 lbs | - |
| Suzuki, Masamune | 3B | Free Agent | 20 | 05/26/2036 | Glendale | USA | Switch | Right | 6' 4" | 190 lbs | - |
| Swanson, Kevin | 3B | Buckhead Bowties | 26 | 04/24/2030 | Mundelein | USA | Right | Right | 6' 2" | 200 lbs | $280,000 |
| Sánchez, Juan | RP | Free Agent | 19 | 07/04/2037 | Retalhuleu | GUA | Right | Right | 5' 9" | 155 lbs | - |
| Sánchez, Rubén | SP | Charleston Battery | 33 | 10/31/2023 | Santiago | CHI | Right | Right | 6' 3" | 200 lbs | $950,000 |
