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| Name | Pos | Team | Age | DOB | POB | Nationality | Bats | Throws | Height | Weight | Salary |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Saelices, Ángel | 3B | Echo Park Lakers | 35 | 02/10/2020 | Santo Domingo | DOM | Right | Right | 5' 9" | 200 lbs | $8,000,000 |
| Salazar, Alonso | SP | Dayton Dirty Reds | 28 | 01/31/2027 | Holguín | CUB | Right | Right | 6' 1" | 200 lbs | $1,000,000 |
| Salgado, Víctor | C | Cape Coral Hurricanes | 25 | 07/27/2030 | La Romana | DOM | Right | Right | 6' 0" | 200 lbs | $280,000 |
| Salinas, José | SP | Hollywood Shredders | 24 | 01/16/2031 | Duvergé | DOM | Left | Left | 6' 5" | 200 lbs | $280,000 |
| San Pedro, Tony | C | Northern Virginia Rainbow Mermaids | 34 | 04/29/2021 | San Pedro Sula | HON | Left | Right | 6' 0" | 200 lbs | $2,580,000 |
| Sanderson, Alan | SP | Echo Park Lakers | 29 | 10/31/2026 | Park Ridge | USA | Left | Right | 5' 10" | 200 lbs | $460,000 |
| Sanford, Steve | SP | Nova Scotia Leviathan | 32 | 10/22/2023 | Berwick | USA | Right | Right | 6' 2" | 200 lbs | $750,000 |
| Sato, Yamato | 1B | Echo Park Lakers | 34 | 10/01/2021 | Tokyo | JPN | Left | Left | 6' 0" | 200 lbs | $10,200,000 |
| Saunders, Leonard | CF | Thunder Bay Northern Lions BC | 33 | 11/06/2022 | New York | USA | Right | Right | 6' 2" | 205 lbs | $632,800 |
| Schmitt, Brian | LF | Free Agent | 23 | 10/21/2032 | Country Club Estates | USA | Right | Right | 6' 2" | 210 lbs | - |
| Scott, Jared | RP | Free Agent | 20 | 10/04/2035 | Cheney | USA | Switch | Right | 6' 5" | 200 lbs | - |
| Shimizu, Yoshiki | RF | Santa Catalina Condor | 34 | 01/26/2021 | Ofunato | JPN | Right | Right | 6' 2" | 200 lbs | $900,000 |
| Shoemaker, Andrew | SP | Thunder Bay Northern Lions BC | 30 | 08/01/2025 | West Long Branch | USA | Right | Right | 6' 0" | 205 lbs | $280,000 |
| Silva, Edgardo | SP | Nova Scotia Leviathan | 18 | 12/16/2037 | Santiago | DOM | Right | Right | 6' 2" | 180 lbs | - |
| Sizemore, Chip | RP | Dayton Dirty Reds | 24 | 07/11/2031 | Tacoma | USA | Right | Right | 6' 2" | 205 lbs | $280,000 |
| Smith, Lance | 2B | Northern Virginia Rainbow Mermaids | 26 | 06/23/2029 | Daly City | USA | Left | Right | 6' 0" | 200 lbs | $280,000 |
| Smythe, Tom | RF | Hollywood Shredders | 41 | 11/22/2014 | Thunder Bay | CAN | Right | Right | 6' 2" | 200 lbs | $1,000,000 |
| Sorondo, Julián | 3B | Las Vegas Flamingos | 31 | 12/05/2024 | Ciudad Bolívar | VEN | Left | Right | 6' 2" | 195 lbs | $14,500,000 |
| Sosa, Claudio | 2B | Thunder Bay Northern Lions BC | 26 | 10/21/2029 | Santiago | DOM | Left | Right | 6' 1" | 200 lbs | $280,000 |
| Sotelo, Gerardo | SS | Dayton Dirty Reds | 25 | 12/18/2030 | Chichicastenango | GUA | Left | Right | 5' 11" | 185 lbs | $280,000 |
| Sottrel, Spencer | C | Las Vegas Flamingos | 26 | 12/06/2029 | Charlotte Amalie | VIR | Left | Right | 6' 1" | 200 lbs | $550,000 |
| Sovaiala, Will | RP | Santa Catalina Condor | 36 | 03/03/2019 | Rochester | USA | Right | Right | 6' 0" | 200 lbs | $280,000 |
| Spilsbury, Bryan | C | Charleston Battery | 27 | 11/25/2028 | South Ockendon | ENG | Switch | Right | 6' 3" | 200 lbs | $5,500,000 |
| Starks, Conor | SP | Santa Catalina Condor | 31 | 03/06/2024 | Lévis | CAN | Switch | Right | 5' 9" | 200 lbs | $18,400,000 |
| Stewart, Nick | SP | Hollywood Shredders | 25 | 01/29/2030 | Neenah | USA | Left | Left | 5' 11" | 180 lbs | $280,000 |
| Stinson, Hunter | RP | Charleston Battery | 26 | 10/28/2029 | Brooklyn | USA | Left | Left | 6' 2" | 200 lbs | $659,400 |
| Stirzacre, Everton | RP | Nova Scotia Leviathan | 34 | 06/14/2021 | Somersham | ENG | Left | Left | 6' 4" | 200 lbs | $620,000 |
| Surtees, Albert | RP | Colorado Billy Goats | 31 | 08/24/2024 | Oldham | ENG | Right | Right | 6' 7" | 200 lbs | $280,000 |
| Swanson, Kevin | 3B | Buckhead Bowties | 25 | 04/24/2030 | Mundelein | USA | Right | Right | 6' 2" | 200 lbs | $280,000 |
| Sánchez, Rubén | SP | Charleston Battery | 32 | 10/31/2023 | Santiago | CHI | Right | Right | 6' 3" | 200 lbs | $950,000 |
