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| Name | Pos | Team | Age | DOB | POB | Nationality | Bats | Throws | Height | Weight | Salary |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Safwan, Basim | RP | MSL Las Vegas Flamingos | 18 | 08/20/2036 | Qazrin | ISR | Right | Right | 6' 2" | 170 lbs | - |
| Salazar, Martino | SP | MSL Nova Scotia Leviathan | 18 | 05/04/2036 | Valencia | VEN | Switch | Left | 6' 2" | 185 lbs | - |
| Salazar, Octávio | 2B | Free Agent | 20 | 11/23/2034 | Belize | BLZ | Left | Right | 6' 4" | 200 lbs | - |
| Sam, Jong-min | SP | MSL Colorado Billy Goats | 18 | 07/18/2036 | Changwon | KOR | Right | Right | 6' 0" | 170 lbs | - |
| Sandoval, Paco | SP | MSL Charleston Battery | 18 | 05/03/2036 | Barcelona | VEN | Right | Right | 6' 2" | 170 lbs | - |
| Sato, Naosuke | CF | MSL Thunder Bay Northern Lions BC | 18 | 11/25/2036 | Toda | JPN | Right | Right | 6' 2" | 175 lbs | - |
| Schoon, Elroy | C | MSL Thunder Bay Northern Lions BC | 16 | 02/23/2038 | Princess Quarter | SIM | Right | Right | 6' 2" | 190 lbs | - |
| Shan, Eng-hee | RF | MSL Northern Virginia Rainbow Mermaids | 17 | 10/29/2037 | Tucheng | TPE | Right | Right | 6' 6" | 200 lbs | - |
| Shanahan, Calvin | SS | MSL D.C. Divided | 17 | 02/13/2037 | Auckland | NZL | Left | Right | 6' 4" | 175 lbs | - |
| Sherman, Justin | SP | MSL Santa Catalina Condor | 17 | 09/07/2037 | Belize | BLZ | Left | Left | 6' 4" | 180 lbs | - |
| Sierra, Luis | CF | MSL Northern Virginia Rainbow Mermaids | 19 | 11/22/2035 | Los Cacaos | DOM | Left | Right | 6' 1" | 170 lbs | - |
| Slocombe, Dominic | LF | MSL Thunder Bay Northern Lions BC | 18 | 06/04/2036 | Kingston | JAM | Right | Right | 6' 5" | 200 lbs | - |
| Snel, Ferdie | 1B | MSL Northern Virginia Rainbow Mermaids | 16 | 01/04/2038 | Tilburg | NED | Right | Right | 6' 2" | 195 lbs | - |
| So, Young-keun | 2B | MSL Detroit Elite | 18 | 04/21/2036 | Seoul | KOR | Right | Right | 6' 1" | 180 lbs | - |
| Solís, Ramón | RP | Free Agent | 19 | 08/15/2035 | Cojutepeque | SLV | Left | Left | 6' 5" | 195 lbs | - |
| Sotelo, Ernesto | RP | Free Agent | 18 | 07/30/2036 | Colón | CRC | Right | Right | 6' 2" | 180 lbs | - |
| Stolk, Nicol | CF | MSL Detroit Elite | 18 | 10/16/2036 | Montaña Rey | CUR | Left | Left | 6' 0" | 175 lbs | - |
| Strijk, Sjelle | RF | MSL Cape Coral Hurricanes | 18 | 07/09/2036 | Cul De Sac | SIM | Left | Left | 6' 4" | 190 lbs | - |
| Sun, Tia | RF | MSL Santa Catalina Condor | 18 | 08/27/2036 | Keelung | TPE | Left | Left | 6' 3" | 190 lbs | - |
| Suzuki, Masamune | RF | MSL Las Vegas Flamingos | 18 | 05/26/2036 | Glendale | USA | Switch | Right | 6' 4" | 190 lbs | - |
| Sánchez, Sancho | CF | MSL Charleston Battery | 18 | 04/30/2036 | Lakewood | USA | Right | Right | 6' 2" | 175 lbs | - |
