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| Name | Pos | Team | Age | DOB | POB | Nationality | Bats | Throws | Height | Weight | Salary |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Salazar, Adrián | SS | MSL Panama City Piranhas | 19 | 12/25/2035 | Buckeye | USA | Right | Right | 6' 2" | 180 lbs | - |
| Salinas, Guillermo | SS | MSL Vancouver Grey Wolves | 17 | 02/11/2037 | Puerto Plata | DOM | Right | Right | 6' 2" | 175 lbs | - |
| Sandoval, Octávio | 3B | MSL Athletic Club KC U-18 | 17 | 07/14/2037 | Chiclayo | PER | Right | Right | 6' 2" | 185 lbs | - |
| Santos, Jorge | SS | MSL Greenville 84s | 19 | 12/19/2035 | Managua | NCA | Right | Right | 6' 2" | 175 lbs | - |
| Serrano, Roberto | SP | MSL New Orleans Voodoo | 18 | 09/24/2036 | Soyapango | SLV | Left | Left | 6' 4" | 195 lbs | - |
| Silva, José | SP | MSL Vancouver Grey Wolves | 17 | 12/14/2037 | Lima | PER | Switch | Right | 5' 11" | 165 lbs | - |
| Sin, Chin-seok | C | MSL Boston Patriots | 17 | 03/01/2037 | Seoul | KOR | Right | Right | 6' 0" | 185 lbs | - |
| Siu, Jing-sheng | 3B | MSL Buffalo White Walkers | 17 | 08/02/2037 | Shanghai | CHN | Right | Right | 6' 2" | 185 lbs | - |
| Smith, Conor | 2B | MSL Pittsburgh Kingfishers | 18 | 10/01/2036 | Coventry | ENG | Right | Right | 6' 2" | 180 lbs | - |
| Solís, Luis | CF | MSL New Orleans Voodoo | 17 | 08/28/2037 | Almansa | ESP | Left | Left | 6' 2" | 175 lbs | - |
| Sosa, Gustavo | SP | MSL Buffalo White Walkers | 17 | 07/24/2037 | Santiago | DOM | Right | Right | 6' 3" | 185 lbs | - |
| Sosa, Jorge | SP | MSL Boston Patriots | 17 | 04/22/2037 | Chimaltenango | GUA | Right | Right | 5' 10" | 155 lbs | - |
| Steenis, Melis | SP | MSL Buffalo White Walkers | 18 | 02/04/2036 | Phillipsburg | SIM | Left | Right | 6' 2" | 175 lbs | - |
| Stinnett, John | RP | Free Agent | 23 | 02/22/2031 | Asheboro | USA | Right | Left | 6' 0" | 175 lbs | - |
| Su, Fu-quan | SP | MSL Pittsburgh Kingfishers | 18 | 07/23/2036 | Xianggangdao | HKG | Left | Left | 6' 2" | 185 lbs | - |
| Subhendu, Avirama | SP | MSL Greenville 84s | 17 | 01/30/2037 | Faridabad | IND | Left | Left | 5' 11" | 160 lbs | - |
| Suzuki, Naoaki | 2B | MSL Boston Patriots | 18 | 09/12/2036 | Otawara | JPN | Left | Right | 6' 3" | 175 lbs | - |
