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| Name | Pos | Team | Age | DOB | POB | Nationality | Bats | Throws | Height | Weight | Salary |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Samurakami, Okakura | 2B | Hartford Pride | 27 | 05/02/2025 | Nagaokakyo | JPN | Right | Right | 6' 1" | 190 lbs | - |
| Sanders, Dan | SP | Austin Black Mambas | 34 | 09/09/2018 | Dunstable | USA | Right | Right | 6' 1" | 200 lbs | - |
| Sang, Jung-jun | DH | Milton Dogfish Head | 25 | 10/06/2027 | Uijeongbu | KOR | Left | Left | 6' 4" | 200 lbs | - |
| Santos, Pancho | 1B | Free Agent | 23 | 12/06/2029 | Carúpano | VEN | Left | Right | 6' 2" | 205 lbs | - |
| Santángel, Juan | CF | Free Agent | 33 | 07/15/2019 | Panama | PAN | Left | Left | 6' 1" | 180 lbs | - |
| Sasaki, Yoshida | SP | Milton Dogfish Head | 30 | 03/30/2022 | Matsue | JPN | Right | Left | 5' 11" | 195 lbs | - |
| Sato, Kuniyuki | 3B | Austin Black Mambas | 27 | 10/13/2025 | Nishinomiya | JPN | Right | Right | 6' 2" | 205 lbs | - |
| Savinon, Pepe | LF | Tortolita Drummers | 31 | 05/11/2021 | Culiacan | MEX | Right | Right | 6' 1" | 205 lbs | $1,600,000 |
| Scarlett, Cliff | SP | Tortolita Drummers | 24 | 03/23/2028 | Saskatoon | CAN | Right | Right | 6' 3" | 200 lbs | - |
| Schreibvogel, Joe | 1B | Free Agent | 35 | 10/05/2017 | Garden City | USA | Left | Right | 6' 2" | 205 lbs | - |
| Seif, Brandon | SP | Pennsauken Flyers | 23 | 05/11/2029 | Botshabelo | RSA | Left | Left | 6' 8" | 195 lbs | - |
| Shaffer, Nelson | RP | Sioux Falls Red Pandas | 23 | 01/18/2029 | Meridian | USA | Switch | Right | 6' 3" | 200 lbs | - |
| Shepard, William | SS | Hartford Pride | 26 | 08/08/2026 | Philadelphia | USA | Left | Right | 6' 0" | 190 lbs | - |
| Shirt, Robert | SP | Sioux Falls Red Pandas | 29 | 12/05/2023 | Spanish Town | JAM | Right | Right | 5' 11" | 195 lbs | - |
| Silva, José | 3B | Ft. Myers Marlins | 26 | 06/12/2026 | Enriquillo | DOM | Left | Right | 6' 0" | 195 lbs | - |
| Sim, Pyeong-ho | 2B | Ft. Myers Marlins | 26 | 03/25/2026 | Seongnam | KOR | Switch | Right | 6' 4" | 200 lbs | - |
| Sims, Jeff | LF | Free Agent | 22 | 01/20/2030 | Keizer | USA | Left | Left | 6' 0" | 190 lbs | - |
| Singh, Soshal Distan | 3B | Tortolita Drummers | 29 | 06/27/2023 | Bangalore | IND | Right | Right | 6' 0" | 200 lbs | $900,000 |
| Snyder, Jason | 1B | Sioux Falls Red Pandas | 24 | 03/11/2028 | New York | USA | Right | Right | 6' 2" | 205 lbs | - |
| So, Jung-kyoo | RP | Free Agent | 28 | 11/08/2024 | Icheon | KOR | Right | Right | 6' 2" | 190 lbs | - |
| Sotelo, Gerardo | SS | Sacramento Redlegs | 22 | 12/18/2030 | Chichicastenango | GUA | Left | Right | 5' 11" | 180 lbs | - |
| Soto, Jaime | 1B | Sioux Falls Red Pandas | 37 | 12/20/2015 | Santiago | CHI | Right | Right | 6' 1" | 205 lbs | $7,500,000 |
| Sottrel, Spencer | C | Santa Barbara Golden Cranes | 23 | 12/06/2029 | Charlotte Amalie | VIR | Left | Right | 6' 1" | 200 lbs | $280,000 |
| Sprengel, Guonçalle | SS | Hartford Pride | 29 | 03/01/2023 | Carúpano | VEN | Right | Right | 6' 1" | 200 lbs | - |
| Stevenson, Ron | CF | Austin Black Mambas | 29 | 12/08/2023 | Suwanee | USA | Left | Left | 6' 4" | 200 lbs | - |
| Stewart, Roy | 2B | Tortolita Drummers | 28 | 01/22/2024 | Hamilton | USA | Right | Right | 6' 4" | 200 lbs | - |
| Stockton, Andrew | RP | Milton Dogfish Head | 24 | 09/08/2028 | Bodmin | ENG | Left | Left | 6' 3" | 195 lbs | - |
| Sturge, Keaton | LF | Austin Black Mambas | 31 | 04/22/2021 | Fredericton | CAN | Right | Right | 6' 0" | 200 lbs | $280,000 |
| Surtees, Albert | SP | Syracuse Squirrel Monkeys | 28 | 08/24/2024 | Oldham | ENG | Right | Right | 6' 7" | 200 lbs | - |
| Suzuarregui, Ramón | SS | Ft. Myers Marlins | 30 | 01/25/2022 | Managua | NCA | Right | Right | 5' 11" | 195 lbs | - |
| Suzuki, Shusui | RP | Tortolita Drummers | 29 | 07/07/2023 | Hiratsuka | JPN | Right | Right | 6' 8" | 205 lbs | - |
| Suárez, Alejandro | SS | Tortolita Drummers | 26 | 01/22/2026 | San Vicente | CRC | Left | Right | 6' 2" | 200 lbs | $280,000 |
| Sánchez, Roberto | SP | Sacramento Redlegs | 23 | 07/06/2029 | Santo Domingo | DOM | Right | Right | 6' 6" | 200 lbs | - |
