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| Name | Pos | Team | Age | DOB | POB | Nationality | Bats | Throws | Height | Weight | Salary |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Sa'id, Reda | RP | Free Agent | 20 | 11/01/2030 | Qazrin | ISR | Switch | Right | 5' 11" | 165 lbs | - |
| Salcido, Armando | LF | MSL Nashville Outlaws | 18 | 07/18/2032 | La Romana | DOM | Left | Left | 6' 1" | 185 lbs | - |
| Salinas, Gabriel | 1B | MSL Buckhead Bowties | 18 | 08/26/2032 | Santa Cruz | ARG | Right | Right | 6' 8" | 220 lbs | - |
| Sapo, Igme | 3B | MSL Toledo Stingers | 18 | 12/06/2032 | Davila | PHI | Right | Right | 6' 3" | 195 lbs | - |
| Sawyer, Johnny | CF | MSL Charleston Battery | 18 | 02/07/2032 | Chattanooga | USA | Left | Left | 6' 4" | 195 lbs | - |
| Schwarzacher, Max | RP | MSL Montana Pandas | 18 | 04/20/2032 | Stanford | USA | Right | Left | 6' 2" | 185 lbs | - |
| Scott, Tom | 3B | MSL Kingston Township Knights | 19 | 11/12/2031 | Conroe | USA | Right | Right | 6' 1" | 190 lbs | - |
| Silva, José | SP | MSL Charleston Battery | 17 | 04/16/2033 | Ciudad Valles | MEX | Right | Right | 6' 0" | 165 lbs | - |
| Sima, Dong-hua | SS | MSL Panama City Piranhas | 17 | 07/09/2033 | Pingtung | TPE | Switch | Right | 6' 2" | 165 lbs | - |
| Smith, Bryant | CF | MSL D.C. Divided | 18 | 03/14/2032 | Manhattan | USA | Right | Right | 6' 2" | 185 lbs | - |
| Snel, Joost | C | MSL Charleston Battery | 18 | 11/24/2032 | Albrandswaard | NED | Right | Right | 6' 1" | 185 lbs | - |
| Soto, Francisco | SP | MSL Kingston Township Knights | 17 | 04/03/2033 | Liberia | CRC | Right | Right | 6' 1" | 175 lbs | - |
| Soto, Pedro | CL | MSL St Louis Coeur | 17 | 08/04/2033 | Higüey | DOM | Left | Right | 6' 6" | 200 lbs | - |
| Spears, Jon | 2B | Free Agent | 22 | 06/27/2028 | San Antonio | USA | Left | Right | 6' 0" | 190 lbs | - |
| Springer, Chris | 1B | MSL St Louis Coeur | 18 | 04/12/2032 | Sioux Falls | USA | Right | Right | 5' 10" | 165 lbs | - |
| Spronck, Neville | SP | MSL Nashville Outlaws | 18 | 07/26/2032 | Willemstad | CUR | Left | Left | 6' 3" | 185 lbs | - |
| Stobert, David | SP | MSL Kingston Township Knights | 17 | 12/11/2033 | Portmore | JAM | Right | Right | 6' 4" | 195 lbs | - |
| Suzuki, Yoshi | SP | MSL Panama City Piranhas | 18 | 11/01/2032 | Sambu | JPN | Switch | Right | 6' 4" | 190 lbs | - |
| Sánchez, Francisco | RF | MSL Thunder Bay Northern Lions BC | 17 | 08/23/2033 | Havana | CUB | Left | Left | 5' 11" | 165 lbs | - |
| Sánchez, Sixto | 2B | MSL Panama City Piranhas | 18 | 03/07/2032 | Bella Vista | PAN | Right | Right | 6' 1" | 170 lbs | - |
| Sánchez, Vincente | SS | MSL D.C. Divided | 18 | 02/13/2032 | Santo Domingo | DOM | Left | Right | 6' 2" | 180 lbs | - |
