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| Name | Pos | Team | Age | DOB | POB | Nationality | Bats | Throws | Height | Weight | Salary |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Sainz, Carlos | RP | Pennsauken Flyers | 23 | 05/23/2027 | Madrid | ESP | Right | Right | 6' 2" | 190 lbs | - |
| Samurakami, Okakura | 2B | Austin Black Mambas | 25 | 05/02/2025 | Nagaokakyo | JPN | Right | Right | 6' 1" | 180 lbs | $280,000 |
| Sanders, Chris | C | Santa Barbara Golden Cranes | 28 | 07/17/2022 | Taylor | USA | Right | Right | 6' 2" | 205 lbs | $280,000 |
| Sanders, Dan | SP | Austin Black Mambas | 32 | 09/09/2018 | Dunstable | USA | Right | Right | 6' 1" | 200 lbs | - |
| Sanderson, Alan | SP | Austin Black Mambas | 24 | 10/31/2026 | Park Ridge | USA | Left | Right | 5' 10" | 200 lbs | - |
| Sato, Yoritomo | 3B | Austin Black Mambas | 37 | 12/10/2013 | Gifu | JPN | Left | Right | 6' 0" | 215 lbs | $280,000 |
| Scott, Dave | SS | Bakersfield Nobles | 30 | 10/31/2020 | New York | USA | Switch | Right | 6' 0" | 180 lbs | - |
| Scotton, Bertrand | RP | Bakersfield Nobles | 31 | 12/30/2019 | Savanna la Mar | JAM | Right | Right | 6' 1" | 190 lbs | $800,000 |
| Shachi, Apaghana | RP | Tortolita Drummers | 26 | 03/18/2024 | Kanpur | IND | Right | Right | 6' 6" | 220 lbs | $280,000 |
| Shepard, Colton | C | Calgary Lynx | 30 | 02/01/2020 | Bensenville | USA | Right | Right | 6' 3" | 205 lbs | $800,000 |
| Shepard, William | SS | Hartford Pride | 24 | 08/08/2026 | Philadelphia | USA | Left | Right | 6' 0" | 180 lbs | - |
| Shimizu, Sumitomo | 2B | Calgary Lynx | 23 | 01/09/2027 | Kitakyushu | JPN | Right | Right | 5' 9" | 175 lbs | - |
| Silva, Jesús | SP | Calgary Lynx | 36 | 06/15/2014 | Newbury | USA | Right | Right | 6' 6" | 215 lbs | $6,500,000 |
| Smith, Dan | RP | Norfolk Pajaritos | 29 | 02/21/2021 | Somers Point | USA | Right | Right | 6' 0" | 200 lbs | - |
| Smith, Roger | CF | Santa Barbara Golden Cranes | 27 | 09/09/2023 | West Laurel | USA | Right | Right | 5' 11" | 195 lbs | - |
| So, Jung-kyoo | RP | Pennsauken Flyers | 26 | 11/08/2024 | Icheon | KOR | Right | Right | 6' 2" | 190 lbs | - |
| Sprengel, Guonçalle | SS | Hartford Pride | 27 | 03/01/2023 | Carúpano | VEN | Right | Right | 6' 1" | 200 lbs | - |
| Spruill, Joe | SP | Pennsauken Flyers | 25 | 12/01/2025 | White City | USA | Right | Right | 6' 1" | 190 lbs | - |
| Stevens, Claude | RP | Ft. Myers Marlins | 29 | 07/04/2021 | Kansas City | USA | Left | Right | 6' 7" | 220 lbs | - |
| Sullivan, David | SP | Bakersfield Nobles | 23 | 07/03/2027 | Wolverine Lake | USA | Switch | Right | 6' 2" | 185 lbs | - |
| Sun, Jai-guo | RF | Norfolk Pajaritos | 31 | 08/08/2019 | Hsinying | TPE | Left | Left | 6' 2" | 200 lbs | $280,000 |
| Suzuarregui, Ramón | SS | Ft. Myers Marlins | 28 | 01/25/2022 | Managua | NCA | Right | Right | 5' 11" | 190 lbs | - |
| Suárez, Alejandro | SS | Tortolita Drummers | 24 | 01/22/2026 | San Vicente | CRC | Left | Right | 6' 2" | 200 lbs | $280,000 |
| Swetnam, Edward | RP | Free Agent | 29 | 06/22/2021 | Charlotte Amalie | VIR | Right | Right | 6' 2" | 200 lbs | - |
| Sánchez, Rodrigo | LF | Calgary Lynx | 28 | 07/15/2022 | Atascocita | USA | Right | Right | 6' 2" | 200 lbs | - |
