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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | ERA | YEAR | Open Career Leaderboard |
|---|---|---|---|---|
| 1 | Héctor Barrera | 1.369 | 2041 | |
| 2 | Hartmann Riedman | 1.449 | 2025 | |
| 3 | Roberto Calderón | 1.839 | 2024 | |
| 4 | Enrique Castro | 1.910 | 2028 | |
| 5 | Javier Roldán | 1.970 | 2022 | |
| 6 | Gary Podell# | 2.052 | 2042 | |
| 7 | Miguel López | 2.055 | 2028 | |
| 8 | Noburo Oishi | 2.071 | 2028 | |
| 9 | Carlos Sánchez | 2.077 | 2020 | |
| 10 | José Cabrera | 2.092 | 2028 | |
| 11 | Kostas Antetokounmpo | 2.120 | 2028 | |
| 12 | Alfonso Rodríguez# | 2.173 | 2049 | |
| 13 | Larry Neal | 2.186 | 2020 | |
| 14 | Cristóbal Román | 2.244 | 2037 | |
| 15 | Zi-cheng Pei | 2.298 | 2040 | |
| 16 | Mark Tucker | 2.323 | 2020 | |
| 17 | Cameron Thoresen | 2.378 | 2039 | |
| 18 | Jared LaBarge# | 2.396 | 2038 | |
| 19 | Atila Freska | 2.404 | 2027 | |
| 20 | Stanley Williams | 2.408 | 2016 | |
| 21 | Sam Johnston | 2.409 | 2038 | |
| 22 | Tsurayaki Tanaka# | 2.414 | 2050 | |
| 23 | Mark Bell | 2.426 | 2024 | |
| 24 | Chin-yau Tu# | 2.448 | 2050 | |
| 25 | Joel Farrell | 2.462 | 2032 | |
| 26 | Oswaldo Mobray | 2.469 | 2024 | |
| 27 | Alfredo Hernández# | 2.476 | 2050 | |
| 28 | Ma Hon Keung | 2.481 | 2027 | |
| 29 | Travis Carson | 2.489 | 2021 | |
| 30 | Joe Dow | 2.526 | 2022 | |
| 31 | Glen Holland | 2.541 | 2024 | |
| 32 | Paco Peña | 2.565 | 2025 | |
| 33 | Luis Hernández | 2.579 | 2024 | |
| 34 | William Robinson# | 2.582 | 2047 | |
| 35 | Jesús Castillo | 2.584 | 2038 | |
| 36 | Clay Pryor | 2.589 | 2032 | |
| 37 | Luis Quintana | 2.628 | 2047 | |
| 38 | Wilson Vélez | 2.630 | 2021 | |
| 39 | Otton Asmus | 2.652 | 2044 | |
| 40 | Mick Alston | 2.657 | 2036 | |
| 41 | John Fowler | 2.660 | 2022 | |
| 42 | Yefim Vistunov# | 2.669 | 2048 | |
| 43 | Miguel López | 2.678 | 2027 | |
| 43 | Ichiro Kumagai# | 2.678 | 2050 | |
| 45 | Roberto Covas | 2.692 | 2025 | |
| 45 | Cameron Thoresen | 2.692 | 2038 | |
| 47 | Pedro Cervantes | 2.694 | 2022 | |
| 48 | Shawn Arnold | 2.695 | 2022 | |
| 49 | Carlos Garza | 2.708 | 2025 | |
| 50 | José Maestas | 2.718 | 2026 | |
| 51 | Song-saeng Kim | 2.726 | 2027 | |
| 52 | Derrick Jones# | 2.735 | 2045 | |
| 53 | José Vélez | 2.742 | 2034 | |
| 53 | Gerald Emerson | 2.742 | 2039 | |
| 55 | Elroy Thompkins | 2.744 | 2027 | |
| 56 | Eric Manchester | 2.760 | 2041 | |
| 57 | Benjamin Busto | 2.763 | 2028 | |
| 58 | José Guillén | 2.765 | 2027 | |
| 59 | Mark Tucker | 2.767 | 2021 | |
| 60 | Allen Simon# | 2.791 | 2047 | |
| 61 | Alton Westrich# | 2.793 | 2040 | |
| 61 | Sam Schultz | 2.793 | 2031 | |
| 63 | Thomas Rivers# | 2.796 | 2048 | |
| 63 | Andy Williams | 2.796 | 2039 | |
| 65 | Alton Westrich# | 2.812 | 2039 | |
| 66 | Louis McDowell | 2.814 | 2027 | |
| 67 | Tadeo Pico | 2.822 | 2032 | |
| 68 | Mick Alston | 2.838 | 2028 | |
| 69 | Phil Miller | 2.842 | 2024 | |
| 69 | Cisco Ortíz | 2.842 | 2025 | |
| 71 | Mike Thornton# | 2.862 | 2050 | |
| 72 | Eric Manchester | 2.865 | 2039 | |
| 73 | Damarco Lyons | 2.878 | 2046 | |
| 74 | Júlio Vázquez | 2.883 | 2028 | |
| 75 | Frank Walker | 2.887 | 2020 | |
| 76 | Joe Griffin | 2.890 | 2025 | |
| 77 | Pedro Herrera | 2.903 | 2032 | |
| 78 | Antenor Elizalde | 2.904 | 2027 | |
| 79 | César Soto | 2.910 | 2035 | |
| 80 | José Pérez | 2.926 | 2047 | |
| 81 | Hong-bin Hua | 2.931 | 2032 | |
| 82 | Elroy Thompkins | 2.941 | 2026 | |
| 83 | Javier Téllez | 2.952 | 2046 | |
| 84 | Curt Tate | 2.954 | 2021 | |
| 85 | Doran Turchin | 2.961 | 2030 | |
| 86 | Juan Gonzáles | 2.965 | 2048 | |
| 87 | Carlos Méndez | 2.966 | 2021 | |
| 88 | Tom Hernández | 2.979 | 2021 | |
| 89 | Rubén Sánchez | 2.981 | 2027 | |
| 89 | Andy Fallon | 2.981 | 2037 | |
| 91 | Jerry Sargent# | 2.991 | 2046 | |
| 92 | Zach Williams Jr. | 3.000 | 2020 | |
| 92 | Ashley Keetley | 3.000 | 2035 | |
| 94 | Felipe Hernández# | 3.009 | 2049 | |
| 95 | Igarashi Momoru | 3.015 | 2034 | |
| 96 | Jesús Árias | 3.016 | 2046 | |
| 96 | Ryan McCall | 3.016 | 2022 | |
| 98 | Larry Larsen# | 3.018 | 2046 | |
| 99 | Bartolo Ramírez | 3.019 | 2021 | |
| 100 | Alfredo Romo | 3.027 | 2042 |
