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| Name | Pos | Team | Age | DOB | POB | Nationality | Bats | Throws | Height | Weight | Salary |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Sa, Zhu | C | Northville Eclipse | 24 | 06/04/2025 | Yuanli | TPE | Switch | Right | 6' 1" | 200 lbs | - |
| Samelo, Bayani | RP | Northville Eclipse | 28 | 03/10/2021 | Iloilo | PHI | Right | Right | 6' 2" | 195 lbs | - |
| Sanders, Paul | 3B | Free Agent | 31 | 07/27/2018 | Hollandale | USA | Right | Right | 6' 2" | 200 lbs | - |
| Sato, Kuniyuki | 3B | Barton Springs Blues | 24 | 10/13/2025 | Nishinomiya | JPN | Right | Right | 6' 2" | 195 lbs | - |
| Savage, Michael | C | Pine Island Dolphins | 25 | 06/17/2024 | West Bountiful | USA | Right | Right | 5' 11" | 195 lbs | - |
| Schmitt, Damien | SP | Providence Pilgrims | 22 | 11/15/2027 | Civrieux-dAzergues | FRA | Right | Right | 6' 8" | 200 lbs | - |
| Schroeder, Chandler | LF | Gwinnett Guinea Pigs | 28 | 11/25/2021 | Boulder | USA | Left | Left | 6' 4" | 200 lbs | - |
| Scott, Curt | 3B | Bethesda Atoms | 25 | 10/03/2024 | Twin Falls | USA | Left | Right | 5' 10" | 195 lbs | - |
| Seif, Brandon | SP | Bethesda Atoms | 20 | 05/11/2029 | Botshabelo | RSA | Left | Left | 6' 8" | 200 lbs | - |
| Shaik, Abdoulaye | 1B | Providence Pilgrims | 24 | 02/04/2025 | al-Aturiyah | QAT | Switch | Right | 6' 1" | 195 lbs | - |
| Sierra, Jesús | CF | Providence Pilgrims | 25 | 05/06/2024 | Fremont | USA | Right | Left | 6' 0" | 200 lbs | - |
| Silva, José | 3B | Pine Island Dolphins | 23 | 06/12/2026 | Enriquillo | DOM | Left | Right | 6' 0" | 190 lbs | - |
| Silva, Tony | 2B | Toledo Saboteurs | 27 | 05/16/2022 | Cleveland | USA | Right | Right | 6' 0" | 200 lbs | - |
| Sim, Pyeong-ho | 2B | Pine Island Dolphins | 23 | 03/25/2026 | Seongnam | KOR | Switch | Right | 6' 4" | 195 lbs | - |
| Simmons, Gerald | SP | Crescent City Krewe | 25 | 01/13/2024 | Scottsdale | USA | Right | Right | 6' 3" | 205 lbs | - |
| Sims, Dennis | RP | Crescent City Krewe | 25 | 09/02/2024 | New York | USA | Right | Right | 6' 7" | 220 lbs | - |
| Spilsbury, Zachary | C | Toledo Saboteurs | 22 | 07/27/2027 | London | ENG | Right | Right | 6' 1" | 200 lbs | - |
| Springer, Mark | SP | Crescent City Krewe | 26 | 01/03/2023 | Belle Chasse | USA | Left | Left | 6' 1" | 195 lbs | - |
| Stevenson, Ron | CF | Barton Springs Blues | 26 | 12/08/2023 | Suwanee | USA | Left | Left | 6' 4" | 205 lbs | - |
| Stewart, Lane | SP | Barton Springs Blues | 25 | 07/06/2024 | Chandler | USA | Switch | Right | 6' 2" | 195 lbs | - |
| Stickells, Bill | RF | St. Petersburg Thunder | 27 | 04/06/2022 | Wayne | USA | Left | Left | 6' 4" | 200 lbs | - |
| Sturge, Keaton | CF | Barton Springs Blues | 28 | 04/22/2021 | Fredericton | CAN | Right | Right | 6' 0" | 205 lbs | - |
| Sugiyama, Yoshihide | SP | Gwinnett Guinea Pigs | 28 | 09/15/2021 | Toyota | JPN | Right | Right | 5' 10" | 200 lbs | - |
| Sulander, Antti-Jussi | RF | Bethesda Atoms | 20 | 04/17/2029 | Kiskorös | HUN | Left | Left | 6' 1" | 170 lbs | - |
| Sullivan, David | RP | Mercer Island Screaming Eagles | 22 | 07/03/2027 | Wolverine Lake | USA | Switch | Right | 6' 2" | 185 lbs | - |
| Suzuki, Shusui | RP | St. Petersburg Thunder | 26 | 07/07/2023 | Hiratsuka | JPN | Right | Right | 6' 8" | 210 lbs | - |
| Sánchez, Ryan | 2B | Providence Pilgrims | 25 | 07/19/2024 | Mt. Lebanon | USA | Right | Right | 6' 2" | 200 lbs | - |
