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| Name | Pos | Team | Age | DOB | POB | Nationality | Bats | Throws | Height | Weight | Salary |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Sacasas, Ernesto | C | Sunset District Fog | 28 | 10/05/2021 | Alotenango | GUA | Switch | Right | 6' 0" | 195 lbs | $280,000 |
| Sainz, Eduardo | C | Pawnee ParksNRec | 29 | 11/06/2020 | Santa Ana | CRC | Right | Right | 6' 0" | 195 lbs | $280,000 |
| Salinas, Valerio | C | Vermont Lake Monsters | 29 | 01/18/2020 | Caracas | VEN | Right | Right | 6' 3" | 205 lbs | - |
| Sandoval, José | C | Vermont Lake Monsters | 25 | 01/09/2024 | Ashland | USA | Right | Right | 6' 2" | 205 lbs | - |
| Sang, Yang-cheng | SP | Hamilton Coyotes | 27 | 03/05/2022 | Liaoyuan | CHN | Left | Left | 6' 6" | 200 lbs | - |
| Sangrey, Thomas | RP | Nolensville Knights | 30 | 03/29/2019 | Madison | USA | Right | Right | 5' 10" | 185 lbs | $1,000,000 |
| Santingo, Ángel | RP | Monongahela Monsters | 23 | 01/15/2026 | Santo Domingo | DOM | Right | Right | 5' 11" | 190 lbs | - |
| Santos, Carlos | RP | Nolensville Knights | 28 | 03/06/2021 | Mao | DOM | Right | Right | 6' 1" | 190 lbs | $470,000 |
| Santos, Luis | 2B | Sioux Falls Red Pandas | 26 | 09/14/2023 | Holguín | CUB | Right | Right | 6' 0" | 200 lbs | $280,000 |
| Saracho, Jaicus | SS | Hamilton Coyotes | 25 | 02/28/2024 | Malasila | PHI | Right | Right | 6' 2" | 200 lbs | - |
| Sardinha, Guaspar | C | Sunset District Fog | 26 | 09/19/2023 | Carapicuíba | BRA | Right | Right | 6' 6" | 215 lbs | - |
| Sasaki, Yoshida | SP | Milton Dogfish Head | 27 | 03/30/2022 | Matsue | JPN | Right | Left | 5' 11" | 185 lbs | - |
| Saunders, Ed | RP | Free Agent | 28 | 06/17/2021 | Indianapolis | USA | Right | Right | 6' 7" | 225 lbs | - |
| Saunders, Leonard | CF | Vermont Lake Monsters | 27 | 11/06/2022 | New York | USA | Right | Right | 6' 2" | 200 lbs | - |
| Saunders, Mason | RP | Pawnee ParksNRec | 32 | 05/04/2017 | Hickory | USA | Right | Right | 6' 8" | 230 lbs | - |
| Searle, Stu | RP | Free Agent | 30 | 09/09/2019 | Ottawa | CAN | Left | Right | 6' 3" | 205 lbs | - |
| Serano, Pedro | 1B | Sioux Falls Red Pandas | 35 | 05/13/2014 | Prairie Village | USA | Left | Left | 6' 6" | 245 lbs | - |
| Shaw, Allen | 2B | Sunset District Fog | 26 | 05/15/2023 | New York | USA | Right | Right | 6' 0" | 200 lbs | - |
| Shibutani, Hidehira | RP | Sioux Falls Red Pandas | 26 | 12/29/2023 | Sendai | JPN | Right | Right | 6' 1" | 190 lbs | - |
| Shimada, Orinosuke | CF | Free Agent | 26 | 12/20/2023 | Fukuoka | JPN | Right | Right | 6' 0" | 190 lbs | - |
| Shoemaker, Andrew | SP | Vermont Lake Monsters | 24 | 08/01/2025 | West Long Branch | USA | Right | Right | 6' 0" | 200 lbs | - |
| Smith, Ben | 1B | Vermont Lake Monsters | 25 | 04/27/2024 | Bellflower | USA | Right | Right | 6' 2" | 200 lbs | - |
| Smith, Jim | SS | Pawnee ParksNRec | 27 | 12/02/2022 | Queens | USA | Right | Right | 6' 0" | 195 lbs | - |
| Smith, Rick | CF | Pawnee ParksNRec | 26 | 10/23/2023 | Pearl City | USA | Left | Left | 6' 2" | 200 lbs | - |
| Smith, Roger | LF | Santa Barbara Golden Cranes | 26 | 09/09/2023 | West Laurel | USA | Right | Right | 5' 11" | 195 lbs | - |
| Smith, Trevor | 2B | Nolensville Knights | 27 | 02/11/2022 | Mt. Airy | USA | Left | Right | 5' 10" | 180 lbs | - |
| Solís, Héctor | CF | Ellenburg Fighting Dachsunds | 30 | 12/10/2019 | Santiago | CHI | Switch | Right | 6' 2" | 195 lbs | - |
| Solís, Javier | RP | Sioux Falls Red Pandas | 30 | 03/28/2019 | San Miguel Chicaj | GUA | Switch | Right | 6' 4" | 195 lbs | - |
| Stabb, Al | 3B | Ellenburg Fighting Dachsunds | 25 | 07/16/2024 | Campbell River | CAN | Switch | Right | 6' 1" | 200 lbs | - |
| Stavely, Dylan | CF | Port Royal Disaster | 28 | 06/17/2021 | Charlotte Amalie | VIR | Right | Right | 6' 2" | 200 lbs | $1,750,000 |
| Stevenson, Arthur | SP | Port Royal Disaster | 29 | 10/09/2020 | Richland Center | USA | Left | Left | 6' 4" | 210 lbs | - |
| Stinchcombe, Gerard | RP | Sunset District Fog | 26 | 04/17/2023 | London | ENG | Left | Left | 5' 10" | 195 lbs | - |
| Summers, Eric | CL | Milton Dogfish Head | 26 | 10/03/2023 | South Jordan | USA | Right | Right | 6' 0" | 200 lbs | - |
| Swetnam, Edward | RP | Free Agent | 28 | 06/22/2021 | Charlotte Amalie | VIR | Right | Right | 6' 2" | 200 lbs | - |
| Sykes, Paul | 2B | Florida Men | 29 | 05/02/2020 | Coventry | ENG | Right | Right | 6' 2" | 195 lbs | - |
| Sánchez, Alberto | 3B | Vermont Lake Monsters | 25 | 08/29/2024 | North Reading | USA | Left | Right | 6' 1" | 195 lbs | - |
| Sánchez, Pedro | 3B | Sioux Falls Red Pandas | 26 | 12/20/2023 | Cancún | MEX | Right | Right | 6' 2" | 205 lbs | - |
