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| Name | Pos | Team | Age | DOB | POB | Nationality | Bats | Throws | Height | Weight | Salary |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Sa'id, Reda | RP | MSL D.C. Divided | 18 | 11/01/2030 | Qazrin | ISR | Switch | Right | 5' 11" | 160 lbs | - |
| Sai, Arata | RP | Free Agent | 18 | 02/18/2030 | Tokyo | JPN | Right | Right | 6' 3" | 180 lbs | - |
| Sala, Viljami | SP | MSL Ft. Worth Cattlemen | 17 | 03/03/2031 | Tatabanya | HUN | Right | Right | 6' 1" | 175 lbs | - |
| Sato, Ienobu | C | MSL Las Vegas Flamingos | 18 | 07/22/2030 | Yokohama | JPN | Switch | Right | 6' 4" | 200 lbs | - |
| Sawyer, Johnny | CF | MSL Charleston Battery | 16 | 02/07/2032 | Chattanooga | USA | Left | Left | 6' 4" | 190 lbs | - |
| Sawyer, Rob | SP | MSL Panama City Piranhas | 19 | 12/06/2029 | Westfield | USA | Right | Right | 6' 0" | 180 lbs | - |
| Schepers, Noud | RP | MSL Thunder Bay Northern Lions BC | 18 | 01/05/2030 | Oranjestad | ARU | Right | Right | 6' 3" | 185 lbs | - |
| Scott, Tom | 3B | MSL Kingston Township Knights | 17 | 11/12/2031 | Conroe | USA | Right | Right | 6' 1" | 185 lbs | - |
| Serrano, Carlos | LF | MSL Panama City Piranhas | 17 | 01/20/2031 | San José de Guanipa | VEN | Right | Right | 6' 3" | 210 lbs | - |
| Shelton, Joe | SS | MSL Toledo Stingers | 17 | 11/02/2031 | Los Angeles | USA | Switch | Right | 6' 1" | 170 lbs | - |
| Sims, Lee | C | MSL Thunder Bay Northern Lions BC | 17 | 04/27/2031 | North Reading | USA | Right | Right | 6' 1" | 200 lbs | - |
| Smit, Ijsbert | RP | MSL Thunder Bay Northern Lions BC | 18 | 02/18/2030 | Seru Grandi | CUR | Left | Left | 6' 1" | 180 lbs | - |
| Smith, Lawrence | RF | Free Agent | 18 | 03/05/2030 | Bloomington | USA | Right | Left | 6' 2" | 200 lbs | - |
| Steele, Steve | SS | MSL D.C. Divided | 17 | 02/14/2031 | Amityville | USA | Right | Right | 6' 2" | 175 lbs | - |
| Stewart, Nick | SP | MSL Oakland Oaks | 18 | 01/29/2030 | Neenah | USA | Left | Left | 5' 11" | 165 lbs | - |
| Styles, Sam | CF | MSL Ft. Worth Cattlemen | 17 | 06/07/2031 | Charlotte Amalie | VIR | Right | Right | 6' 2" | 180 lbs | - |
| Sánchez, José | 2B | MSL Ft. Worth Cattlemen | 18 | 10/18/2030 | Lagunillas | VEN | Right | Right | 6' 3" | 185 lbs | - |
