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| Name | Pos | Team | Age | DOB | POB | Nationality | Bats | Throws | Height | Weight | Salary |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Salas, Gabriel | SP | MSL Cleveland Browns | 19 | 11/18/2029 | Maracaibo | VEN | Left | Left | 6' 0" | 175 lbs | - |
| Schroeder, Carl | CF | MSL Montana Pandas | 17 | 01/17/2031 | Chapmanville | USA | Right | Right | 6' 0" | 160 lbs | - |
| Schroeder, Dan | 3B | MSL Buffalo White Walkers | 17 | 09/22/2031 | Houston | USA | Right | Right | 6' 3" | 200 lbs | - |
| Seletto, Bonifazio | RP | MSL Pittsburgh Kingfishers | 17 | 01/23/2031 | Rosario | ARG | Right | Right | 6' 2" | 175 lbs | - |
| Shi, Lung | RP | MSL Cleveland Browns | 17 | 01/15/2031 | Pingtung | TPE | Right | Right | 5' 11" | 160 lbs | - |
| Sihvonen, Kauno | SS | MSL Buffalo White Walkers | 17 | 04/19/2031 | Nyergesújfalu | HUN | Right | Right | 6' 1" | 180 lbs | - |
| Silva, Esteban | SS | MSL Long Island Lighthouse | 18 | 02/11/2030 | Buenos Aires | ARG | Right | Right | 6' 4" | 185 lbs | - |
| Silva, Manny | 3B | MSL Montana Pandas | 17 | 09/06/2031 | Sosúa | DOM | Right | Right | 6' 4" | 195 lbs | - |
| Silva, Pedro | RP | Free Agent | 19 | 06/09/2029 | Jarabacoa | DOM | Right | Right | 5' 11" | 165 lbs | - |
| Simha, Balanatha | 3B | MSL Buffalo White Walkers | 17 | 02/03/2031 | Pune Cantonment | IND | Right | Right | 6' 3" | 185 lbs | - |
| Sin, Seong-rae | RP | MSL Montana Pandas | 18 | 01/06/2030 | Pyongyang | PRK | Right | Left | 6' 1" | 170 lbs | - |
| Siraj, Saqr | C | MSL Pittsburgh Kingfishers | 16 | 04/01/2032 | Ramat Gan | ISR | Right | Right | 6' 1" | 180 lbs | - |
| Siu, Liu-chun | LF | MSL Cleveland Browns | 17 | 02/05/2031 | Fengshan | TPE | Right | Right | 6' 0" | 180 lbs | - |
| Smith, Ed | 2B | MSL Echo Park Lakers | 17 | 10/11/2031 | Independence | USA | Right | Right | 5' 10" | 170 lbs | - |
| Smith, Tim | RP | MSL Seattle Rocketeers | 16 | 01/15/2032 | Covington | USA | Left | Left | 6' 0" | 165 lbs | - |
| Sugano, Ryuichi | SS | MSL Buffalo White Walkers | 17 | 03/11/2031 | Chigasaki | JPN | Right | Right | 6' 1" | 175 lbs | - |
| Sutkamp, Frank | SP | MSL Montana Pandas | 19 | 12/11/2029 | Nieuwkoop | NED | Right | Right | 6' 2" | 180 lbs | - |
| Suárez, Alfonso | SP | MSL Pittsburgh Kingfishers | 18 | 06/07/2030 | Neyba | DOM | Right | Right | 6' 0" | 180 lbs | - |
| Sánchez, Jesús | SP | MSL Colorado Billy Goats | 17 | 10/04/2031 | Nizao | DOM | Left | Left | 6' 2" | 180 lbs | - |
