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| Name | Pos | Team | Age | DOB | POB | Nationality | Bats | Throws | Height | Weight | Salary |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Sackett, John | SP | Flint Crush | 19 | 04/27/2029 | Birmingham | USA | Right | Right | 6' 6" | 200 lbs | - |
| Sakai, Yasunobu | 2B | Germantown Uruguayans | 18 | 04/13/2030 | Kusatsu | JPN | Right | Right | 5' 11" | 175 lbs | - |
| Salazar, Rodrigo | 1B | Watford City Trash Pandas | 19 | 04/26/2029 | Solana Beach | USA | Right | Right | 6' 0" | 195 lbs | - |
| Sanford, Eric | SP | Free Agent | 23 | 08/18/2025 | Cesar Chavez | USA | Left | Left | 6' 4" | 205 lbs | - |
| Satiro, Gustavo | CF | Bompton Baby Lakers | 22 | 12/29/2026 | Rome | ITA | Right | Right | 6' 0" | 180 lbs | - |
| Sawyer, Michael | SP | Memphis Music | 19 | 07/20/2029 | Milwaukee | USA | Right | Right | 6' 8" | 210 lbs | - |
| Schalk, Reggie | SP | Memphis Music | 20 | 08/06/2028 | Willemstad | CUR | Right | Right | 6' 3" | 190 lbs | - |
| Serrano, Jesús | CF | Bethlehem Angel Kitties | 18 | 04/23/2030 | Tegucigalpa | HON | Right | Right | 6' 4" | 175 lbs | - |
| Shantsev, Jov | 1B | Shady Side Zoomies | 20 | 07/23/2028 | Moscow | RUS | Right | Right | 6' 0" | 190 lbs | - |
| Silva, Roberto | SP | Memphis Music | 19 | 06/13/2029 | Camagüey | CUB | Left | Left | 6' 4" | 190 lbs | - |
| Sinke, Marnix | 3B | Twinsburg Tigers | 20 | 05/20/2028 | Princess Quarter | SIM | Right | Right | 6' 2" | 190 lbs | - |
| Smith, Matt | RP | Bethlehem Angel Kitties | 20 | 07/09/2028 | Manhattan | USA | Right | Right | 6' 3" | 185 lbs | - |
| Smith, Mike | RF | Memphis Music | 20 | 04/22/2028 | Sanford | USA | Right | Right | 6' 3" | 200 lbs | - |
| Smith, Nelson | CF | Bethlehem Angel Kitties | 19 | 07/19/2029 | Lakewood | USA | Left | Left | 5' 9" | 165 lbs | - |
| Soto, Luis | C | Twinsburg Tigers | 20 | 06/29/2028 | Mexico City | MEX | Right | Right | 6' 2" | 190 lbs | - |
| Souza, José | SP | Memphis Music | 19 | 11/17/2029 | Santo Domingo | DOM | Right | Right | 6' 0" | 170 lbs | - |
| Spaan, Gerben | RF | Bompton Baby Lakers | 20 | 01/26/2028 | Cul De Sac | SIM | Left | Left | 6' 3" | 200 lbs | - |
| Spargo, Kian | RP | Germantown Uruguayans | 16 | 01/26/2032 | Cruz Bay | VIR | Right | Right | 6' 6" | 190 lbs | - |
| Stewart, Harry | CF | Hicksville Hounds | 19 | 02/05/2029 | South Lancaster | USA | Left | Right | 6' 0" | 170 lbs | - |
| Suarez, Rafael | SS | Memphis Music | 21 | 09/27/2027 | Pag-Asa | PHI | Right | Right | 6' 3" | 185 lbs | - |
| Suzuki, Ichizo | RP | Memphis Music | 18 | 07/16/2030 | Nara | JPN | Left | Left | 6' 5" | 190 lbs | - |
| Suzuki, Kazunori | CF | Twinsburg Tigers | 21 | 11/30/2027 | Niiza | JPN | Switch | Right | 6' 2" | 190 lbs | - |
| Suárez, Héctor | 3B | Germantown Uruguayans | 19 | 07/14/2029 | Santiago | CHI | Right | Right | 6' 3" | 195 lbs | - |
| Synder, Jim | 2B | Watford City Trash Pandas | 20 | 08/27/2028 | Tucson | USA | Right | Right | 6' 4" | 190 lbs | - |
| Sánchez, Orlando | SP | Flint Crush | 20 | 03/30/2028 | Puerto Padre | CUB | Right | Right | 5' 10" | 160 lbs | - |
