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| Name | Pos | Team | Age | DOB | POB | Nationality | Bats | Throws | Height | Weight | Salary |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Sackett, Mike | 2B | Squirrel Hill Pierogis | 27 | 06/30/2021 | Chicago | USA | Right | Right | 5' 9" | 175 lbs | - |
| Sainz, Carlos | SP | Bethesda Atoms | 21 | 05/23/2027 | Madrid | ESP | Right | Right | 6' 2" | 180 lbs | - |
| Sanders, Homer | SP | Gwinnett Guinea Pigs | 27 | 09/11/2021 | Philadelphia | USA | Right | Right | 6' 2" | 205 lbs | - |
| Sanders, Paul | 3B | Free Agent | 30 | 07/27/2018 | Hollandale | USA | Right | Right | 6' 2" | 200 lbs | - |
| Sandoval, César | SP | Providence Pilgrims | 28 | 07/28/2020 | Santiago de Cuba | CUB | Right | Right | 6' 7" | 220 lbs | - |
| Sandín, Mauro | SP | Free Agent | 30 | 11/21/2018 | Santiago | CRC | Right | Right | 6' 4" | 205 lbs | - |
| Schneider, Elijah | RF | Billings Polar Bears | 25 | 09/20/2023 | West Brattleboro | USA | Left | Left | 6' 6" | 210 lbs | - |
| Schroeder, Chandler | LF | Gwinnett Guinea Pigs | 27 | 11/25/2021 | Boulder | USA | Left | Left | 6' 4" | 200 lbs | - |
| Scott, Curt | 3B | Bethesda Atoms | 24 | 10/03/2024 | Twin Falls | USA | Left | Right | 5' 10" | 190 lbs | - |
| Seif, Brandon | SP | Bethesda Atoms | 19 | 05/11/2029 | Botshabelo | RSA | Left | Left | 6' 8" | 200 lbs | - |
| Seshu, Anil | RP | Chesapeake Cangrejos Fantasmas | 25 | 04/27/2023 | Behta Hajipur | IND | Right | Right | 6' 8" | 205 lbs | - |
| Shafer, Monte | 3B | Billings Polar Bears | 25 | 12/31/2023 | Walnut Creek | USA | Switch | Right | 6' 2" | 200 lbs | - |
| Shaik, Abdoulaye | 1B | Providence Pilgrims | 23 | 02/04/2025 | al-Aturiyah | QAT | Switch | Right | 6' 1" | 185 lbs | - |
| Shepherd, Wyatt | C | Providence Pilgrims | 25 | 03/06/2023 | Austintown | USA | Right | Right | 6' 2" | 200 lbs | - |
| Silva, José | 3B | Akron Blimps | 22 | 06/12/2026 | Enriquillo | DOM | Left | Right | 6' 0" | 185 lbs | - |
| Silva, Luis | RP | Ithaca Fighting Imps | 26 | 08/09/2022 | Mexico City | MEX | Left | Left | 6' 0" | 195 lbs | - |
| Silva, Tony | 2B | Toledo Saboteurs | 26 | 05/16/2022 | Cleveland | USA | Right | Right | 6' 0" | 200 lbs | - |
| Sim, Pyeong-ho | 2B | Akron Blimps | 22 | 03/25/2026 | Seongnam | KOR | Switch | Right | 6' 4" | 185 lbs | - |
| Sims, Mark | C | Chesapeake Cangrejos Fantasmas | 25 | 03/09/2023 | Lake Charles | USA | Right | Right | 5' 10" | 195 lbs | - |
| Sims, Nathan | SP | Billings Polar Bears | 23 | 10/05/2025 | Toledo | USA | Right | Right | 6' 2" | 195 lbs | - |
| Small, Chris | SP | Chesapeake Cangrejos Fantasmas | 23 | 07/27/2025 | Cincinnati | USA | Left | Right | 6' 2" | 200 lbs | - |
| Smith, Dan | RP | Chesapeake Cangrejos Fantasmas | 27 | 02/21/2021 | Somers Point | USA | Right | Right | 6' 0" | 205 lbs | - |
| Spruill, Joe | SP | Bethesda Atoms | 23 | 12/01/2025 | White City | USA | Right | Right | 6' 1" | 185 lbs | - |
| Stark, Paul | RP | Bethesda Atoms | 24 | 08/01/2024 | North Bellmore | USA | Right | Right | 6' 2" | 200 lbs | - |
| Sterling, Dan | 3B | Free Agent | 25 | 01/11/2023 | Hartford | USA | Right | Right | 6' 4" | 200 lbs | - |
| Strain, Bill | SP | Ithaca Fighting Imps | 23 | 12/10/2025 | North Little Rock | USA | Left | Left | 6' 4" | 215 lbs | - |
| Sturge, Keaton | CF | Barton Springs Blues | 27 | 04/22/2021 | Fredericton | CAN | Right | Right | 6' 0" | 200 lbs | - |
| Sugiyama, Yoshihide | SP | Gwinnett Guinea Pigs | 27 | 09/15/2021 | Toyota | JPN | Right | Right | 5' 10" | 200 lbs | - |
| Sánchez, Cristo | SP | Toledo Saboteurs | 23 | 09/08/2025 | Barva | CRC | Left | Left | 6' 1" | 185 lbs | - |
| Sánchez, Pedro | 3B | Billings Polar Bears | 25 | 12/20/2023 | Cancún | MEX | Right | Right | 6' 2" | 200 lbs | - |
| Sánchez, Ryan | 2B | Providence Pilgrims | 24 | 07/19/2024 | Mt. Lebanon | USA | Right | Right | 6' 2" | 200 lbs | - |
