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| Name | Pos | Team | Age | DOB | POB | Nationality | Bats | Throws | Height | Weight | Salary |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Saelices, Ángel | SS | Nova Scotia Leviathan | 27 | 02/10/2020 | Santo Domingo | DOM | Right | Right | 5' 9" | 180 lbs | $4,600,000 |
| Saksansin, Poom | RP | Nova Scotia Leviathan | 27 | 10/07/2020 | Chiang Khong | THA | Right | Right | 6' 3" | 200 lbs | $360,000 |
| Salas, Jorge | SP | Greenville 84s | 17 | 03/23/2030 | Santo Domingo | DOM | Left | Left | 6' 1" | 170 lbs | - |
| Salazar, José | CL | Seattle Rocketeers | 31 | 06/05/2016 | Las Tunas | CUB | Right | Right | 6' 1" | 200 lbs | $465,501 |
| Salinas, José | SP | Hollywood Shredders | 16 | 01/16/2031 | Duvergé | DOM | Left | Left | 6' 5" | 180 lbs | - |
| Sandison, Len | CF | Nova Scotia Leviathan | 25 | 10/13/2022 | Marion | USA | Left | Left | 6' 0" | 195 lbs | $280,000 |
| Santana, José | C | Vancouver Grey Wolves | 17 | 10/13/2030 | Ciudad Guayana | VEN | Right | Right | 6' 0" | 185 lbs | - |
| Santos, Pancho | 1B | Hollywood Shredders | 18 | 12/06/2029 | Carúpano | VEN | Left | Right | 6' 2" | 200 lbs | - |
| Sato, Munemitsu | 1B | Northern Virginia Rainbow Mermaids | 17 | 06/22/2030 | Misawa | JPN | Right | Right | 6' 0" | 190 lbs | - |
| Sato, Yamato | 1B | Hollywood Shredders | 26 | 10/01/2021 | Tokyo | JPN | Left | Left | 6' 0" | 220 lbs | $13,600,000 |
| Saunders, Mason | SP | Long Island Lighthouse | 30 | 05/04/2017 | Hickory | USA | Right | Right | 6' 8" | 240 lbs | $280,000 |
| Savage, Michael | C | Free Agent | 23 | 06/17/2024 | West Bountiful | USA | Right | Right | 5' 11" | 190 lbs | - |
| Schaller, Ari | RP | St. Louis Coeur | 26 | 04/20/2021 | Eggendorf | AUT | Right | Right | 6' 1" | 200 lbs | $280,000 |
| Scotton, Bertrand | RP | Boston Patriots | 28 | 12/30/2019 | Savanna la Mar | JAM | Right | Right | 6' 1" | 190 lbs | $460,000 |
| Seco, Javier | 1B | Free Agent | 33 | 08/01/2014 | Changuinola | PAN | Left | Left | 6' 3" | 220 lbs | - |
| Security, Maxwell | RP | Vancouver Grey Wolves | 29 | 10/06/2018 | Dallas | USA | Right | Right | 6' 2" | 200 lbs | $280,000 |
| Sedin, Andor | SP | Free Agent | 25 | 10/22/2022 | Tulsa | USA | Left | Left | 6' 2" | 200 lbs | - |
| Sellers, Ricky | SP | Hollywood Shredders | 32 | 01/28/2015 | Oro Valley | USA | Switch | Right | 6' 0" | 200 lbs | $8,860,000 |
| Serrano, Adrián | C | Hollywood Shredders | 25 | 04/07/2022 | San Pedro de Macorís | DOM | Right | Right | 6' 0" | 200 lbs | $280,000 |
| Serrano, Jesús | CF | Long Island Lighthouse | 17 | 04/23/2030 | Tegucigalpa | HON | Right | Right | 6' 4" | 175 lbs | - |
| Seth, Sadiya | CF | Free Agent | 30 | 03/31/2017 | Bafata | GNB | Right | Left | 5' 11" | 190 lbs | - |
| Seymour, Todd | 3B | Free Agent | 22 | 02/12/2025 | Nashville | USA | Right | Right | 6' 3" | 200 lbs | - |
| Shaw, Bobby | SP | Free Agent | 29 | 10/17/2018 | Parkwood | USA | Right | Right | 6' 1" | 200 lbs | - |
| Shini, Yaichiro | SP | Vancouver Grey Wolves | 23 | 09/27/2024 | Kashihara | JPN | Right | Right | 6' 6" | 205 lbs | $280,000 |
| Sierra, Jesús | CF | Free Agent | 23 | 05/06/2024 | Fremont | USA | Right | Left | 6' 0" | 195 lbs | - |
| Sijne, Nalle | SP | Athletic Club KC | 18 | 08/24/2029 | Willemstad | CUR | Right | Right | 6' 9" | 205 lbs | - |
| Silva, Esteban | SS | Long Island Lighthouse | 17 | 02/11/2030 | Buenos Aires | ARG | Right | Right | 6' 4" | 185 lbs | - |
| Silva, Gilberto | RF | Boston Patriots | 17 | 11/05/2030 | San Alejo | SLV | Right | Right | 6' 2" | 170 lbs | - |
| Silva, Jesús | SP | Greenville 84s | 33 | 06/15/2014 | Newbury | USA | Right | Right | 6' 6" | 225 lbs | $28,200,000 |
| Sinclair, Jacob | SP | Long Island Lighthouse | 27 | 09/26/2020 | Louisville | USA | Switch | Right | 6' 2" | 200 lbs | $280,000 |
| Slooters, Peer | SP | Boston Patriots | 29 | 01/10/2018 | Willemstad | CUR | Right | Right | 6' 4" | 190 lbs | $1,620,000 |
| Smalls, Robert | RP | Boston Patriots | 36 | 06/27/2011 | Union Grove | USA | Right | Right | 6' 2" | 200 lbs | $840,000 |
| Smith, Barrett | RP | Free Agent | 29 | 12/22/2018 | Los Angeles | USA | Right | Right | 6' 2" | 205 lbs | - |
| Smythe, Tom | RF | Northern Virginia Rainbow Mermaids | 33 | 11/22/2014 | Thunder Bay | CAN | Right | Right | 6' 2" | 200 lbs | $14,300,000 |
| Song, Su-hyeon | SP | Vancouver Grey Wolves | 18 | 08/06/2029 | Daegu | KOR | Switch | Right | 6' 2" | 180 lbs | - |
| Sotelo, Gerardo | SS | Hollywood Shredders | 17 | 12/18/2030 | Chichicastenango | GUA | Left | Right | 5' 11" | 170 lbs | - |
| Soto, Jaime | 1B | St. Louis Coeur | 32 | 12/20/2015 | Santiago | CHI | Right | Right | 6' 1" | 200 lbs | $20,000,000 |
| Sovaiala, Will | RP | Nova Scotia Leviathan | 28 | 03/03/2019 | Rochester | USA | Right | Right | 6' 0" | 200 lbs | $410,000 |
| Spadina, Chuck | RP | Northern Virginia Rainbow Mermaids | 26 | 08/10/2021 | Redwood City | USA | Left | Right | 6' 0" | 200 lbs | $280,000 |
| Sparrow, Sean | C | Free Agent | 22 | 05/22/2025 | Sioux Falls | USA | Left | Right | 6' 0" | 190 lbs | - |
| Stafford, Dave | RP | Nova Scotia Leviathan | 27 | 12/03/2020 | Boyne City | USA | Left | Left | 6' 2" | 205 lbs | $280,000 |
| Stavely, Dylan | CF | Long Island Lighthouse | 26 | 06/17/2021 | Charlotte Amalie | VIR | Right | Right | 6' 2" | 195 lbs | $650,000 |
| Stengel, Greg | RP | Seattle Rocketeers | 27 | 11/13/2020 | Bailey's Crossroads | USA | Left | Left | 6' 0" | 190 lbs | $280,000 |
| Stirzacre, Everton | RP | Nova Scotia Leviathan | 26 | 06/14/2021 | Somersham | ENG | Left | Left | 6' 4" | 200 lbs | $280,000 |
| Stout, Chris | RP | Free Agent | 28 | 06/27/2019 | Seattle | USA | Left | Right | 6' 3" | 210 lbs | - |
| Strickland, Jeffrey | RP | Athletic Club KC | 26 | 01/26/2021 | St. Cloud | USA | Right | Right | 6' 3" | 200 lbs | $280,000 |
| Suggett, Glenn | SP | Boston Patriots | 32 | 09/27/2015 | Los Angeles | USA | Right | Right | 6' 1" | 200 lbs | $9,000,000 |
| Sugimoto, Mitsuoki | SS | Hollywood Shredders | 24 | 05/07/2023 | Matsudo | JPN | Left | Right | 6' 4" | 200 lbs | $7,700,000 |
| Sun, Ni | CF | St. Louis Coeur | 18 | 08/11/2029 | Shiongshui | HKG | Right | Right | 5' 10" | 160 lbs | - |
| Suzuki, Ichizo | SP | St. Louis Coeur | 17 | 07/16/2030 | Nara | JPN | Left | Left | 6' 5" | 190 lbs | - |
| Swan, Ishaan | 3B | Greenville 84s | 21 | 01/07/2026 | St. George | BER | Left | Right | 6' 0" | 165 lbs | $280,000 |
| Swaneveld, Irving | SP | St. Louis Coeur | 18 | 04/13/2029 | Cole Bay | SIM | Switch | Left | 6' 2" | 180 lbs | - |
| Sánchez, Félix | SP | Nova Scotia Leviathan | 17 | 02/27/2030 | San Pedro de Macorís | DOM | Left | Left | 6' 2" | 175 lbs | - |
| Sánchez, Roberto | SP | Hollywood Shredders | 18 | 07/06/2029 | Santo Domingo | DOM | Right | Right | 6' 6" | 200 lbs | - |
