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| Name | Pos | Team | Age | DOB | POB | Nationality | Bats | Throws | Height | Weight | Salary |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Saelices, Juan Andrés | RP | Athletic Club KC Reserves | 26 | 09/07/2020 | Gorham | USA | Right | Right | 6' 0" | 190 lbs | - |
| Saksansin, Poom | RP | Salt Lake City Buzz | 26 | 10/07/2020 | Chiang Khong | THA | Right | Right | 6' 3" | 200 lbs | $360,000 |
| Salas, José | CF | Jersey City Tritons | 27 | 06/30/2019 | Dajabón | DOM | Right | Right | 6' 0" | 200 lbs | - |
| Salmi, Aatos | SS | Hialeah Dodos | 27 | 12/22/2019 | Kiskorös | HUN | Right | Right | 6' 2" | 185 lbs | - |
| Santana, Rodrigo | 3B | Monongahela Monsters | 29 | 12/28/2017 | San Diego | USA | Switch | Right | 5' 11" | 200 lbs | - |
| Sarcoma, Broderick | 2B | Hialeah Dodos | 32 | 08/13/2014 | Mayagüez | PUR | Right | Right | 5' 10" | 200 lbs | - |
| Scott, Dave | SS | Bakersfield Nobles | 26 | 10/31/2020 | New York | USA | Switch | Right | 6' 0" | 175 lbs | - |
| Secada, Diego Alejandro | 1B | Plymouth Rocks | 29 | 05/25/2017 | Desemparados | CRC | Switch | Right | 6' 5" | 235 lbs | - |
| Shirt, Robert | SP | Alaskan Humpbacks | 23 | 12/05/2023 | Spanish Town | JAM | Right | Right | 5' 11" | 175 lbs | - |
| Simpson, John | 3B | Alaskan Humpbacks | 25 | 11/02/2021 | Memphis | USA | Right | Right | 5' 11" | 180 lbs | - |
| Sinclair, Jacob | SP | Hartford Pride | 26 | 09/26/2020 | Louisville | USA | Switch | Right | 6' 2" | 200 lbs | - |
| Situ, Zee-loo | 2B | Bakersfield Nobles | 25 | 06/25/2021 | Shijiazhuang | CHN | Right | Right | 6' 1" | 195 lbs | - |
| Soto, Rafael | 3B | Hartford Pride | 26 | 01/05/2020 | Villa Alemana | CHI | Left | Right | 5' 9" | 175 lbs | - |
| Sparks, Clyde | RP | Hialeah Dodos | 30 | 05/07/2016 | Casper | USA | Right | Right | 6' 0" | 200 lbs | - |
| Stengel, Greg | RP | Pennsauken Flyers | 26 | 11/13/2020 | Bailey's Crossroads | USA | Left | Left | 6' 0" | 190 lbs | $280,000 |
| Steur, Gustaf | RP | Monongahela Monsters | 23 | 08/21/2023 | Willemstad | CUR | Left | Right | 6' 6" | 210 lbs | - |
| Swan, Ishaan | 3B | Alaskan Humpbacks | 20 | 01/07/2026 | St. George | BER | Left | Right | 6' 0" | 165 lbs | - |
