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| Wednesday, November 15th , 2045 |
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| Barton Springs Blues: RP Chun-mei Bao becomes a free-agent. |
| Monday, November 13th , 2045 |
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| Lake Minnetonka Love Boats: Signed Manager Javier Martínez. |
| Monday, November 6th , 2045 |
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| Lake Minnetonka Love Boats: Activated CL Jasper Smulders from the injured list. |
| Lake Minnetonka Love Boats: Activated CL Ángel López from the injured list. |
| Lake Minnetonka Love Boats: Activated SP Jim Murray from the injured list. |
| Lake Minnetonka Love Boats: Activated RP Mark Adams from the injured list. |
| Friday, November 3rd , 2045 |
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| Minnesota Loons: Signed Manager David Cross. |
| Thursday, October 26th , 2045 |
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| Ithaca Fighting Imps: 2B Trent Davis retired from professional baseball. |
| Casper Ghosts: RP Pancho Covarrubias retired from professional baseball. |
| Ithaca Fighting Imps: 3B Shi-yu Ting retired from professional baseball. |
| Irving Blue Sox: 2B Bobby Verstraten retired from professional baseball. |
| Ithaca Fighting Imps: RP Daniel Tucker retired from professional baseball. |
| Billings Polar Bears: 3B Don Hartman retired from professional baseball. |
| Ithaca Fighting Imps: 1B Robbie Care retired from professional baseball. |
| Irving Blue Sox: RF Bruce Hampton retired from professional baseball. |
| Ithaca Fighting Imps: 2B Phil Underwood retired from professional baseball. |
| Lake Minnetonka Love Boats: 1B António González retired from professional baseball. |
| Billings Polar Bears: RP Pablo Mareno retired from professional baseball. |
| Barton Springs Blues: RP Ralph Dunn retired from professional baseball. |
| Billings Polar Bears: RP Vernon Jacobs retired from professional baseball. |
| Yakima Hops: Hitting Coach Henry Potts leaves the team, his contract was not renewed |
| Lancaster Farmers: Hitting Coach Orlando Deleón leaves the team, his contract was not renewed |
| Casper Ghosts: Manager Manuel Romo leaves the team, his contract was not renewed |
| Casper Ghosts: Pitching Coach Mike Rushing leaves the team, his contract was not renewed |
