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| Monday, November 6th , 2045 |
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| Kingston Mangos: Activated SP Scott Powell from the injured list. |
| Kingston Mangos: Activated RP Scott Childers from the injured list. |
| Friday, November 3rd , 2045 |
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| Alameda Airmen: Signed Manager Markus Richardson. |
| Walla Walla Walleye: Signed Manager Eddie O'Bryan. |
| Thursday, October 26th , 2045 |
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| Lake Erie Arryns: C Jun Hasegawa retired from professional baseball. |
| Lake Erie Arryns: C Kaseeb bin Yunus retired from professional baseball. |
| Lake Erie Arryns: SP Ricardo Hernández retired from professional baseball. |
| Kingston Mangos: CF Félix Tiemblo retired from professional baseball. |
| Lake Erie Arryns: C Wan-ling Xú retired from professional baseball. |
| Grand Forks Caterpillars: RF Jermaine Tuttle retired from professional baseball. |
| Kingston Mangos: 1B Tom Childress retired from professional baseball. |
| Kingston Mangos: RF Danny Brown retired from professional baseball. |
| Kingston Mangos: C Carlos Ariñez retired from professional baseball. |
| Niagara Falls Expos: Manager Alan Manor retires. |
| Walla Walla Walleye: Pitching Coach Craig Buckner leaves the team, his contract was not renewed |
| Walla Walla Walleye: Manager Erik Davis leaves the team, his contract was not renewed |
| Alameda Airmen: Manager Javier Martínez leaves the team, his contract was not renewed |
| Syracuse Storm: Hitting Coach Steve O'Hickey leaves the team, his contract was not renewed |
| Mancelona Torch: Manager Marshall Edwards leaves the team, his contract was not renewed |
| Cut Off Crawdads: Hitting Coach Raúl Romero leaves the team, his contract was not renewed |
