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| Monday, November 6th , 2045 |
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| Kingston Mangos: Activated SP Scott Powell from the injured list. |
| Kingston Mangos: Activated RP Scott Childers from the injured list. |
| Friday, November 3rd , 2045 |
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| Alameda Airmen: Signed Manager Markus Richardson. |
| Walla Walla Walleye: Signed Manager Eddie O'Bryan. |
| Thursday, October 26th , 2045 |
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| 2B Marvin Russell retired from professional baseball. |
| RP António Aguilar retired from professional baseball. |
| C Joon-suk Kim retired from professional baseball. |
| 3B Martín González retired from professional baseball. |
| Lake Erie Arryns: C Jun Hasegawa retired from professional baseball. |
| C Juan Carlos Solís retired from professional baseball. |
| RP Chang-soo Pak retired from professional baseball. |
| 1B Kobbe Elders retired from professional baseball. |
| Lake Erie Arryns: C Kaseeb bin Yunus retired from professional baseball. |
| RP Tim Stroud retired from professional baseball. |
| 3B Luwen Cullus retired from professional baseball. |
| 3B José López retired from professional baseball. |
| CF Santiago Jiménez retired from professional baseball. |
| RP Gerald Cain retired from professional baseball. |
| 2B Elijah Conway retired from professional baseball. |
| RF Ernie Knight retired from professional baseball. |
| C Freddy Ordóñez retired from professional baseball. |
| RP Ánibal Montoya retired from professional baseball. |
| Lake Erie Arryns: SP Ricardo Hernández retired from professional baseball. |
| RP Paul Elkins retired from professional baseball. |
| RP Tom Simon retired from professional baseball. |
| Kingston Mangos: CF Félix Tiemblo retired from professional baseball. |
| Lake Erie Arryns: C Wan-ling Xú retired from professional baseball. |
| Grand Forks Caterpillars: RF Jermaine Tuttle retired from professional baseball. |
| Kingston Mangos: 1B Tom Childress retired from professional baseball. |
| RP Bob Byrd retired from professional baseball. |
| 1B Sonny Jones retired from professional baseball. |
| Kingston Mangos: RF Danny Brown retired from professional baseball. |
| Kingston Mangos: C Carlos Ariñez retired from professional baseball. |
| 3B Guo Dong retired from professional baseball. |
| Niagara Falls Expos: Manager Alan Manor retires. |
| Walla Walla Walleye: Pitching Coach Craig Buckner leaves the team, his contract was not renewed |
| Walla Walla Walleye: Manager Erik Davis leaves the team, his contract was not renewed |
| Alameda Airmen: Manager Javier Martínez leaves the team, his contract was not renewed |
| Syracuse Storm: Hitting Coach Steve O'Hickey leaves the team, his contract was not renewed |
| Mancelona Torch: Manager Marshall Edwards leaves the team, his contract was not renewed |
| Cut Off Crawdads: Hitting Coach Raúl Romero leaves the team, his contract was not renewed |
