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| Name | Pos | Team | Age | DOB | POB | Nationality | Bats | Throws | Height | Weight | Salary |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Sacasas, Ernesto | C | Pawnee ParksNRec | 23 | 10/05/2021 | Alotenango | GUA | Switch | Right | 6' 0" | 195 lbs | - |
| Sachs, Eddie | 1B | Athletic Club KC Reserves | 37 | 09/27/2007 | Allentown | USA | Right | Right | 6' 2" | 255 lbs | - |
| Sainz, Eduardo | C | Pawnee ParksNRec | 24 | 11/06/2020 | Santa Ana | CRC | Right | Right | 6' 0" | 190 lbs | - |
| Salazar, Zacarías | 3B | Forest City Warriors | 28 | 02/27/2016 | San Luis Potosí | MEX | Right | Right | 6' 1" | 200 lbs | - |
| Salviati, Valerio | CF | Pawnee ParksNRec | 22 | 06/25/2022 | Sabara | BRA | Right | Right | 6' 2" | 175 lbs | - |
| Sanders, Jason | RP | Syracuse Starks | 32 | 12/12/2012 | Prichard | USA | Right | Right | 6' 2" | 225 lbs | - |
| Sarcoma, Broderick | 2B | Hialeah Dodos | 30 | 08/13/2014 | Mayagüez | PUR | Right | Right | 5' 10" | 190 lbs | - |
| Scanlan, Oakland | RP | Forest City Warriors | 30 | 06/08/2014 | Salem | USA | Right | Right | 6' 8" | 250 lbs | - |
| Schroeder, Chandler | LF | Syracuse Squirrel Monkeys | 23 | 11/25/2021 | Boulder | USA | Left | Left | 6' 4" | 210 lbs | - |
| Scott, Jerry | RF | Syracuse Squirrel Monkeys | 26 | 01/25/2018 | Elizabethtown | USA | Right | Right | 6' 2" | 205 lbs | - |
| Sellers, Cameron | RP | Ellenburg Fighting Dachsunds | 28 | 07/22/2016 | Pasco | USA | Right | Right | 6' 1" | 215 lbs | - |
| Shamakani, Dean | LF | Kansas Rainbeaus | 27 | 07/06/2017 | George | RSA | Right | Right | 6' 3" | 210 lbs | $280,000 |
| Shu, Huang-di | 3B | Tortolita Drummers | 25 | 10/30/2019 | Tachi | TPE | Switch | Right | 5' 10" | 190 lbs | - |
| Slaughter, Bill | RP | Pawnee ParksNRec | 24 | 05/27/2020 | Markham | USA | Right | Right | 5' 11" | 190 lbs | - |
| Smith, Bob | C | Forest City Warriors | 24 | 09/18/2020 | West Jordan | USA | Right | Right | 6' 0" | 215 lbs | - |
| Snodgrass, Roger | 3B | Free Agent | 31 | 10/27/2013 | New York | USA | Right | Right | 6' 4" | 245 lbs | - |
| Somoza, Ean | SP | Free Agent | 31 | 09/15/2013 | Omaha | USA | Right | Right | 5' 10" | 180 lbs | - |
| Sparks, Clyde | RP | Hialeah Dodos | 28 | 05/07/2016 | Casper | USA | Right | Right | 6' 0" | 195 lbs | - |
| Spillane, Bren | SS | Tortolita Drummers | 31 | 02/19/2013 | Versailles | USA | Switch | Right | 6' 1" | 190 lbs | $4,500,000 |
| Srivastav, Abhipala | CF | Syracuse Squirrel Monkeys | 27 | 05/08/2017 | Rohtak | IND | Right | Right | 6' 3" | 200 lbs | - |
| Stanley, Carter | 1B | Kansas Rainbeaus | 24 | 11/16/2020 | Tamalpais-Homestead Valley | USA | Left | Left | 6' 6" | 250 lbs | - |
| Stevenson, Arthur | SP | Hamilton Coyotes | 24 | 10/09/2020 | Richland Center | USA | Left | Left | 6' 4" | 220 lbs | - |
| Stickells, Bill | RF | Tortolita Drummers | 22 | 04/06/2022 | Wayne | USA | Left | Left | 6' 4" | 195 lbs | - |
| Stokes, Dan | RP | Syracuse Squirrel Monkeys | 26 | 04/19/2018 | Portland | USA | Left | Left | 6' 3" | 210 lbs | - |
| Strickland, Jeffrey | RP | Athletic Club KC Reserves | 23 | 01/26/2021 | St. Cloud | USA | Right | Right | 6' 3" | 200 lbs | - |
| Sullivan, Patrick | 2B | Ellenburg Fighting Dachsunds | 26 | 12/22/2018 | Tucson | USA | Switch | Right | 6' 0" | 200 lbs | - |
