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| Name | Pos | Team | Age | DOB | POB | Nationality | Bats | Throws | Height | Weight | Salary |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Saelices, Juan Andrés | RP | Athletic Club KC Academy | 23 | 09/07/2020 | Gorham | USA | Right | Right | 6' 0" | 190 lbs | - |
| Salas, Bill | SP | Lake Minnetonka Love Boats | 25 | 06/23/2018 | Santa Ana | USA | Left | Left | 6' 3" | 215 lbs | - |
| Salinas, Juan | RP | Asheville Highlanders | 26 | 08/10/2017 | Aibonito | PUR | Left | Right | 6' 1" | 190 lbs | - |
| Salinas, Valerio | C | Lancaster Farmers | 23 | 01/18/2020 | Caracas | VEN | Right | Right | 6' 3" | 210 lbs | - |
| San Pedro, Tony | C | Barton Springs Blues | 22 | 04/29/2021 | San Pedro Sula | HON | Left | Right | 6' 0" | 195 lbs | - |
| Sánchez, Tomás | DH | Billings Polar Bears | 24 | 06/28/2019 | Santiago de Cuba | CUB | Switch | Left | 6' 0" | 195 lbs | - |
| Sanders, Paul | SS | Minnesota Loons | 25 | 07/27/2018 | Hollandale | USA | Right | Right | 6' 2" | 195 lbs | - |
| Santana, Rubén | RP | Asheville Highlanders | 24 | 06/03/2019 | Hartshorne | USA | Switch | Right | 6' 4" | 210 lbs | - |
| Saunders, Carl | LF | Marquette Miners | 27 | 05/24/2016 | Gresham | USA | Switch | Right | 6' 1" | 205 lbs | - |
| Schmidt, Kelvin | 1B | Billings Polar Bears | 24 | 08/06/2019 | Cul De Sac | SIM | Left | Right | 6' 1" | 205 lbs | - |
| Schulte, Steffen | CF | Barton Springs Blues | 25 | 07/01/2018 | Dallastown | USA | Right | Right | 6' 0" | 200 lbs | - |
| Scott, Mike | 2B | Toledo Saboteurs | 24 | 12/29/2019 | San Antonio | USA | Left | Right | 6' 0" | 190 lbs | - |
| Selemani, Yaw | CL | Lancaster Farmers | 22 | 11/30/2021 | Benoni | RSA | Right | Right | 6' 1" | 180 lbs | - |
| Shallcross, Nathan | CF | Irving Blue Sox | 23 | 04/17/2020 | New York | USA | Left | Left | 6' 1" | 180 lbs | - |
| Shiu, Xie-li | 2B | Toledo Saboteurs | 24 | 08/09/2019 | Taichung | TPE | Left | Right | 6' 1" | 200 lbs | - |
| Shreeve, Tim | RP | Billings Polar Bears | 26 | 08/24/2017 | Fresno | USA | Right | Right | 6' 0" | 215 lbs | - |
| Skinner, Jason | RP | Asheville Highlanders | 26 | 09/02/2017 | Monongahela | USA | Right | Right | 5' 10" | 180 lbs | - |
| Smith, Steve | RP | Minnesota Loons | 23 | 07/21/2020 | New York | USA | Left | Left | 5' 9" | 170 lbs | - |
| Solís, Héctor | CF | Marquette Miners | 24 | 12/10/2019 | Santiago | CHI | Switch | Right | 6' 2" | 200 lbs | - |
| Sosa, Armando | SP | Toledo Saboteurs | 26 | 12/14/2017 | Santiago | CHI | Right | Right | 6' 0" | 185 lbs | - |
| Soto, Alonso | RP | Toledo Saboteurs | 24 | 12/27/2019 | Ayapa | HON | Left | Left | 6' 4" | 190 lbs | - |
| Souza, Júlio | CF | Minnesota Loons | 26 | 11/07/2017 | Vicente Noble | DOM | Left | Left | 6' 1" | 190 lbs | - |
| Stafford, Dave | SP | Richland Rails | 23 | 12/03/2020 | Boyne City | USA | Left | Left | 6' 2" | 200 lbs | - |
| Steel, Jim | SP | Lancaster Farmers | 22 | 12/01/2021 | Andover | USA | Left | Left | 6' 2" | 205 lbs | - |
| Stephens, Phil | SP | Toledo Saboteurs | 24 | 01/05/2019 | Whitney | USA | Right | Left | 5' 10" | 180 lbs | - |
| Stevens, Ron | RP | Billings Polar Bears | 25 | 10/22/2018 | Garner | USA | Left | Right | 6' 0" | 205 lbs | - |
| Stevens, William | RP | Yakima Hops | 20 | 05/17/2023 | Bell Gardens | USA | Left | Left | 6' 4" | 195 lbs | - |
| Strickland, Jeffrey | RP | Athletic Club KC Academy | 22 | 01/26/2021 | St. Cloud | USA | Right | Right | 6' 3" | 195 lbs | - |
| Strong, Tim | RP | Richland Rails | 20 | 02/16/2023 | Quincy | USA | Left | Left | 6' 4" | 195 lbs | - |
