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| Name | Pos | Team | Age | DOB | POB | Nationality | Bats | Throws | Height | Weight | Salary |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Saito, Sen | RP | South Beach Blaze | 21 | 03/11/2022 | Hachioji | JPN | Left | Left | 6' 1" | 175 lbs | - |
| Salas, Juan | RP | Eugene Vandals | 21 | 03/10/2022 | San Francisco de Macorís | DOM | Right | Right | 6' 4" | 190 lbs | - |
| Samelo, Bayani | RP | Caldwell Chiefs | 22 | 03/10/2021 | Iloilo | PHI | Right | Right | 6' 2" | 180 lbs | - |
| Sanders, Homer | SP | Eugene Vandals | 22 | 09/11/2021 | Philadelphia | USA | Right | Right | 6' 2" | 210 lbs | - |
| Sandoval, César | RP | Levittown Blue Dragons | 23 | 07/28/2020 | Santiago de Cuba | CUB | Right | Right | 6' 7" | 225 lbs | - |
| Santos, José | SP | Levittown Blue Dragons | 23 | 09/08/2020 | San Rafael Abajo | CRC | Right | Right | 6' 3" | 185 lbs | - |
| Sariana, Ánibal | 2B | Eugene Vandals | 21 | 01/25/2022 | Ciudad Guayana | VEN | Right | Right | 6' 2" | 180 lbs | - |
| Sato, Ken'ichi | RF | Eugene Vandals | 20 | 07/09/2023 | Omihachiman | JPN | Left | Left | 5' 11" | 180 lbs | - |
| Schultz, Johnny | RF | Eugene Vandals | 22 | 12/26/2021 | New York | USA | Right | Left | 6' 4" | 200 lbs | - |
| Scott, Dave | SS | South Beach Blaze | 23 | 10/31/2020 | New York | USA | Switch | Right | 6' 0" | 170 lbs | - |
| Sedlaczek, Vratislav | SP | Lake Erie Arryns | 25 | 11/01/2018 | Svitavy | CZE | Switch | Right | 6' 6" | 205 lbs | - |
| Seema, Shu-yaan | 3B | Rocky Mountain Vibes | 22 | 11/13/2021 | Saigong | HKG | Right | Right | 6' 4" | 205 lbs | - |
| Semprún, Ramón | 2B | Rocky Mountain Vibes | 24 | 07/29/2019 | Catia La Mar | VEN | Right | Right | 5' 11" | 190 lbs | - |
| Shannon, Paul | SP | Delmarva Gallos | 22 | 12/03/2021 | Runnemede | USA | Right | Right | 6' 2" | 195 lbs | - |
| Shimizu, Takayuki | SP | Rocky Mountain Vibes | 22 | 07/22/2021 | Tokyo | JPN | Left | Left | 6' 1" | 180 lbs | - |
| Sigurdson, Leland | CF | Grim Reapers | 20 | 02/01/2023 | Phoenix | USA | Right | Right | 5' 11" | 170 lbs | - |
| Silva, Luis | RP | South Beach Blaze | 21 | 08/09/2022 | Mexico City | MEX | Left | Left | 6' 0" | 175 lbs | - |
| Simmons, Lance | SP | Myrtle Beach Seahawks | 24 | 09/20/2019 | Sunnyvale | USA | Left | Left | 6' 1" | 185 lbs | - |
| Simpson, John | 3B | Myrtle Beach Seahawks | 22 | 11/02/2021 | Memphis | USA | Right | Right | 5' 11" | 170 lbs | - |
| Smith, Joe | 3B | Chicago Tula | 23 | 10/26/2020 | Fountain Hills | USA | Right | Right | 6' 1" | 195 lbs | - |
| Solano, Paco | RP | Lake Erie Arryns | 24 | 01/28/2019 | San Juan | PUR | Right | Left | 6' 1" | 195 lbs | - |
| Soliman, Nestor | C | Delmarva Gallos | 19 | 08/21/2024 | Maragondon | PHI | Right | Right | 6' 2" | 190 lbs | - |
| Soto, Rafael | 3B | Levittown Blue Dragons | 23 | 01/05/2020 | Villa Alemana | CHI | Left | Right | 5' 9" | 175 lbs | - |
| Spadina, Chuck | SP | Chicago Tula | 22 | 08/10/2021 | Redwood City | USA | Left | Right | 6' 0" | 195 lbs | - |
| Sprengel, Guonçalle | SS | Eugene Vandals | 20 | 03/01/2023 | Carúpano | VEN | Right | Right | 6' 1" | 185 lbs | - |
| Stephens, José | RP | Chicago Tula | 21 | 06/25/2022 | Staten Island | USA | Right | Right | 5' 9" | 170 lbs | - |
| Stewart, Roy | SS | Grim Reapers | 19 | 01/22/2024 | Hamilton | USA | Right | Right | 6' 4" | 185 lbs | - |
| Stewart, Tom | RP | Grim Reapers | 24 | 09/07/2019 | Sandusky | USA | Switch | Right | 6' 3" | 205 lbs | - |
| Stirzacre, Everton | SP | Rocky Mountain Vibes | 22 | 06/14/2021 | Somersham | ENG | Left | Left | 6' 4" | 205 lbs | - |
| Stroud, Tim | SP | Lake Erie Arryns | 23 | 09/23/2020 | Garden Grove | USA | Right | Right | 6' 7" | 220 lbs | - |
| Stuart, Bailey | CF | Myrtle Beach Seahawks | 21 | 08/18/2022 | Neston | ENG | Switch | Right | 6' 2" | 185 lbs | - |
| Sun, Ching | 3B | Delmarva Gallos | 22 | 04/07/2021 | Taipei | TPE | Right | Right | 5' 10" | 180 lbs | - |
| Suzuki, Shusui | RP | Grim Reapers | 20 | 07/07/2023 | Hiratsuka | JPN | Right | Right | 6' 8" | 215 lbs | - |
