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| Name | Pos | Team | Age | DOB | POB | Nationality | Bats | Throws | Height | Weight | Salary |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Sainz, Eduardo | C | Tacoma Fur Traders | 22 | 11/06/2020 | Santa Ana | CRC | Right | Right | 6' 0" | 185 lbs | - |
| Salas, Lúcio | SP | Providence Pilgrims | 26 | 01/02/2016 | Caracas | VEN | Right | Right | 6' 2" | 200 lbs | - |
| Salmi, Aatos | SS | Virginia Beach Whales | 23 | 12/22/2019 | Kiskorös | HUN | Right | Right | 6' 2" | 175 lbs | - |
| Sánchez, Adrián | C | St. Petersburg Thunder | 29 | 12/15/2013 | Terrytown | USA | Right | Right | 5' 11" | 220 lbs | - |
| Sánchez, Manuel | RP | Lancaster Farmers | 23 | 08/09/2019 | Guacimo | CRC | Right | Right | 6' 8" | 225 lbs | - |
| Santos, José | RP | Toledo Saboteurs | 28 | 07/13/2014 | Los Angeles | USA | Left | Left | 6' 1" | 210 lbs | - |
| Scribbner, Thom | 2B | Casper Ghosts | 26 | 11/21/2016 | Santa Cruz | USA | Right | Right | 6' 2" | 210 lbs | - |
| Shannon, Rob | CF | Ottawa Nationals | 26 | 12/19/2016 | Birmingham | USA | Right | Right | 6' 0" | 190 lbs | - |
| Shannon, Robert | 1B | Lancaster Farmers | 22 | 07/08/2020 | Paradise | USA | Left | Right | 6' 0" | 200 lbs | - |
| Shen, Qi-zhen | 1B | Casper Ghosts | 23 | 07/29/2019 | Kangshan | TPE | Left | Right | 6' 1" | 205 lbs | - |
| Shiu, Xie-li | 2B | Toledo Saboteurs | 23 | 08/09/2019 | Taichung | TPE | Left | Right | 6' 1" | 195 lbs | - |
| Smith, Mark | SP | Casper Ghosts | 23 | 11/06/2019 | Queens | USA | Right | Right | 6' 2" | 205 lbs | - |
| Smith, Tim | RP | Lancaster Farmers | 25 | 03/17/2017 | Hiram | USA | Right | Right | 6' 0" | 190 lbs | - |
| Sparks, Clyde | SP | Virginia Beach Whales | 26 | 05/07/2016 | Casper | USA | Right | Right | 6' 0" | 190 lbs | - |
| Srivastav, Abhipala | CF | Atlantic City Sonics | 25 | 05/08/2017 | Rohtak | IND | Right | Right | 6' 3" | 190 lbs | - |
| St. John, John | SP | Providence Pilgrims | 26 | 04/09/2016 | Scott | USA | Switch | Right | 6' 0" | 195 lbs | - |
| Stevens, Marvin | SP | Lancaster Farmers | 24 | 11/25/2018 | Maynardville | USA | Right | Right | 6' 5" | 230 lbs | - |
| Stevenson, Arthur | SP | Ottawa Nationals | 22 | 10/09/2020 | Richland Center | USA | Left | Left | 6' 4" | 210 lbs | - |
| Surgener, Richard | RP | Biloxi Shuckers | 20 | 01/11/2022 | Oceanside | USA | Right | Right | 6' 2" | 185 lbs | - |
| Suto, Teika | SP | Providence Pilgrims | 27 | 05/25/2015 | Kawasaki | JPN | Right | Left | 6' 4" | 200 lbs | - |
