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| Name | Pos | Team | Age | DOB | POB | Nationality | Bats | Throws | Height | Weight | Salary |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Sagastizabal, Salvador | RP | Sioux Falls Red Pandas | 32 | 09/28/2010 | Cúcuta | COL | Right | Right | 6' 6" | 225 lbs | $280,000 |
| Salcido, Carlos | RP | Milton Dogfish Head | 32 | 09/23/2010 | El Cercado | DOM | Right | Right | 5' 10" | 165 lbs | $800,000 |
| Salinas, Marcos | RP | Sunset District Fog | 26 | 12/01/2016 | Xaloztoc | MEX | Right | Right | 6' 1" | 195 lbs | - |
| Samson, Igme | 3B | Calgary Lynx | 30 | 11/05/2012 | San Carlos | PHI | Right | Right | 6' 0" | 210 lbs | - |
| Santiago, Rafael | RP | Austin Black Mambas | 29 | 10/27/2013 | Yara | CUB | Right | Right | 5' 11" | 195 lbs | - |
| Santos, Jim | C | Calgary Lynx | 23 | 01/15/2019 | Toledo | USA | Switch | Right | 6' 5" | 235 lbs | - |
| Sarkar, Syed | 1B | Free Agent | 32 | 02/20/2010 | Dinajpur | BAN | Right | Right | 6' 3" | 240 lbs | - |
| Sassetti, Timoteo | RP | Sioux Falls Red Pandas | 31 | 12/30/2011 | Caltanissetta | ITA | Right | Right | 5' 10" | 180 lbs | - |
| Scott, Cody | SS | Sunset District Fog | 26 | 04/25/2016 | Thomasville | USA | Right | Right | 6' 1" | 190 lbs | - |
| Security, Maxwell | RP | Calgary Lynx | 24 | 10/06/2018 | Dallas | USA | Right | Right | 6' 2" | 205 lbs | - |
| Seki, Kojuro | C | Athletic Club KC Reserves | 23 | 09/03/2019 | Naha | JPN | Right | Right | 6' 2" | 210 lbs | - |
| Shadix, Byron | RF | Pennsauken Flyers | 24 | 02/08/2018 | Mesa | USA | Right | Right | 6' 3" | 200 lbs | - |
| Shiu, Quan | RP | Free Agent | 33 | 12/27/2009 | Taipei | TPE | Left | Left | 6' 5" | 210 lbs | - |
| Shortall, Rod | LF | Free Agent | 32 | 12/01/2010 | Saint-Jérôme | CAN | Right | Right | 6' 1" | 200 lbs | - |
| Shuo, Tso-lin | RF | Santa Barbara Golden Cranes | 27 | 02/22/2015 | Huinan | CHN | Left | Left | 5' 11" | 195 lbs | - |
| Silva, Mario | SP | Calgary Lynx | 24 | 07/10/2018 | Sparta | USA | Right | Right | 6' 1" | 190 lbs | - |
| Simic, Pavle | SP | Sioux Falls Red Pandas | 29 | 06/10/2013 | Botevgrad | BUL | Right | Left | 6' 7" | 225 lbs | $280,000 |
| Sin, Man-su | LF | Austin Black Mambas | 24 | 03/13/2018 | Sunchon | PRK | Left | Left | 6' 2" | 195 lbs | - |
| Smith, Adam | 1B | Monongahela Monsters | 27 | 03/22/2015 | Haddington | SCO | Right | Right | 6' 1" | 190 lbs | $1,155,000 |
| Snider, Roy | CF | Austin Black Mambas | 30 | 12/08/2012 | East Los Angeles | USA | Switch | Left | 6' 0" | 190 lbs | - |
| Snodgrass, Roger | 3B | Monongahela Monsters | 29 | 10/27/2013 | New York | USA | Right | Right | 6' 4" | 245 lbs | $280,000 |
| Somoza, Ean | RP | Monongahela Monsters | 29 | 09/15/2013 | Omaha | USA | Right | Right | 5' 10" | 175 lbs | $280,000 |
| Soto, Javier | SP | Salt Lake City Buzz | 26 | 12/14/2016 | Ciudad Bolívar | VEN | Left | Right | 6' 4" | 210 lbs | - |
| Soto, Phil | SP | Sioux Falls Red Pandas | 27 | 07/26/2015 | Long Beach | USA | Right | Right | 6' 4" | 210 lbs | $280,000 |
| Souza, Júlio | CF | Calgary Lynx | 25 | 11/07/2017 | Vicente Noble | DOM | Left | Left | 6' 1" | 185 lbs | - |
| Sovaiala, Will | CL | Salt Lake City Buzz | 23 | 03/03/2019 | Rochester | USA | Right | Right | 6' 0" | 190 lbs | - |
| Speranza, Paolo | RP | Sunset District Fog | 26 | 10/30/2016 | Valencia | VEN | Switch | Left | 5' 10" | 175 lbs | - |
| Starr, Jamie | 3B | Santa Barbara Golden Cranes | 25 | 10/26/2017 | Carolina | PUR | Left | Right | 6' 3" | 210 lbs | $280,000 |
| Sterling, Raheem | 1B | Free Agent | 28 | 03/14/2014 | Kingston | JAM | Right | Right | 6' 2" | 225 lbs | - |
| Steur, Phil | SP | Monongahela Monsters | 24 | 05/24/2018 | Zwartewaterland | NED | Switch | Right | 6' 0" | 185 lbs | $280,000 |
| Stones, Rutland | RP | Austin Black Mambas | 29 | 02/12/2013 | Apache Junction | USA | Right | Right | 6' 0" | 200 lbs | - |
| Stuterberg, Harry | SP | Santa Barbara Golden Cranes | 32 | 10/06/2010 | New York | USA | Right | Right | 6' 2" | 210 lbs | - |
| Suisha, Yasunobu | SP | Monongahela Monsters | 24 | 03/24/2018 | Kimitsu | JPN | Left | Left | 6' 6" | 215 lbs | - |
