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| Name | Pos | Team | Age | DOB | POB | Nationality | Bats | Throws | Height | Weight | Salary |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Saelices, Ángel | SS | Brooklyn Dodgers | 22 | 02/10/2020 | Santo Domingo | DOM | Right | Right | 5' 9" | 160 lbs | $280,000 |
| Sáenz, Orlando | CF | Vancouver Grey Wolves | 17 | 03/07/2025 | Santiago | DOM | Switch | Right | 5' 10" | 155 lbs | - |
| Sánchez, Arturo | SP | Toledo Stingers | 20 | 10/27/2022 | Chilibre | PAN | Right | Right | 6' 2" | 185 lbs | - |
| Sánchez, Javier | 1B | Vancouver Grey Wolves | 38 | 03/01/2004 | Villa Vazquez | DOM | Left | Left | 6' 5" | 260 lbs | $1,100,000 |
| Sánchez, Mariano | RF | Pittsburgh Kingfishers | 17 | 09/01/2025 | Las Cumbres | PAN | Right | Right | 6' 5" | 195 lbs | - |
| Santángel, Juan | LF | Nashville Outlaws | 23 | 07/15/2019 | Panama | PAN | Left | Left | 6' 1" | 175 lbs | $1,571,500 |
| Santegoeds, Buddy | SP | Toledo Stingers | 19 | 03/16/2023 | Princess Quarter | SIM | Right | Right | 6' 1" | 180 lbs | - |
| Santingo, Ángel | SP | Pittsburgh Kingfishers | 16 | 01/15/2026 | Santo Domingo | DOM | Right | Right | 5' 11" | 160 lbs | - |
| Santos, Jorge | SP | Montana Pandas | 18 | 03/08/2024 | El Progreso | HON | Right | Right | 6' 4" | 195 lbs | - |
| Santos, José | SS | Montana Pandas | 33 | 06/17/2009 | Carora | VEN | Right | Right | 6' 2" | 215 lbs | $3,300,000 |
| Saracho, Jaicus | CF | Kingston Township Knights | 18 | 02/28/2024 | Malasila | PHI | Right | Right | 6' 2" | 175 lbs | - |
| Saracho, Nestor | CF | D.C. Divided | 17 | 01/25/2025 | Cainta | PHI | Left | Left | 5' 11" | 165 lbs | - |
| Sarcoma, Broderick | 2B | Nashville Outlaws | 28 | 08/13/2014 | Mayagüez | PUR | Right | Right | 5' 10" | 180 lbs | $1,800,000 |
| Sardinha, Guaspar | C | D.C. Divided | 19 | 09/19/2023 | Carapicuíba | BRA | Right | Right | 6' 6" | 215 lbs | - |
| Sato, Kuniyuki | 3B | Echo Park Lakers | 17 | 10/13/2025 | Nishinomiya | JPN | Right | Right | 6' 2" | 180 lbs | - |
| Sato, Yoritomo | 3B | Free Agent | 29 | 12/10/2013 | Gifu | JPN | Left | Right | 6' 0" | 215 lbs | - |
| Satyavrat, Manoo | LF | Seattle Rocketeers | 37 | 08/15/2005 | Pehlad Pur Bangar | IND | Left | Left | 6' 2" | 200 lbs | $1,000,000 |
| Saunders, Mason | SP | Toledo Stingers | 25 | 05/04/2017 | Hickory | USA | Right | Right | 6' 8" | 240 lbs | $280,000 |
| Sawada, Sawao | SP | Oakland Oaks | 17 | 09/29/2025 | Ichihara | JPN | Right | Right | 6' 1" | 175 lbs | - |
| Sawyer, Davis | SP | Panama City Piranhas | 31 | 03/21/2011 | Shawnee | USA | Right | Right | 6' 5" | 230 lbs | $650,000 |
| Schreibvogel, Joe | 1B | Echo Park Lakers | 25 | 10/05/2017 | Garden City | USA | Left | Right | 6' 2" | 235 lbs | $280,000 |
| Schumacher, Keith | 2B | Panama City Piranhas | 17 | 05/14/2025 | Sint Michiel | CUR | Left | Right | 6' 2" | 170 lbs | - |
| Schwer, Vern | SP | Brooklyn Dodgers | 17 | 04/07/2025 | Auckland | NZL | Left | Left | 6' 2" | 175 lbs | - |
| Scott, Jimmy | C | Vancouver Grey Wolves | 32 | 03/15/2010 | Bronx | USA | Right | Right | 6' 5" | 230 lbs | $550,000 |
| Scott, Yu-bao | SP | Oakland Oaks | 17 | 06/29/2025 | Toowoomba | AUS | Right | Right | 6' 1" | 175 lbs | - |
| Scruggins, Carsello | RF | Panama City Piranhas | 28 | 07/18/2014 | Halawa | USA | Right | Right | 6' 1" | 210 lbs | $5,000,000 |
| Segar, Evan | 1B | Panama City Piranhas | 17 | 07/20/2025 | Kingston | JAM | Left | Left | 6' 0" | 190 lbs | - |
| Sellers, Ricky | SP | Toledo Stingers | 27 | 01/28/2015 | Oro Valley | USA | Switch | Right | 6' 0" | 190 lbs | $8,860,000 |
| Serano, Pedro | 1B | Toledo Stingers | 28 | 05/13/2014 | Prairie Village | USA | Left | Left | 6' 6" | 255 lbs | $3,520,000 |
| Sergeant, Colm | 2B | Kingston Township Knights | 17 | 07/18/2025 | Charlotte Amalie | VIR | Right | Right | 6' 1" | 180 lbs | - |
| Seymour, Dan | CL | Las Vegas Flamingos | 22 | 03/04/2020 | Canton | USA | Right | Right | 6' 2" | 190 lbs | $280,000 |
| Shinn, Chan-ho | 3B | Las Vegas Flamingos | 24 | 02/02/2018 | Incheon | KOR | Left | Right | 6' 2" | 210 lbs | $10,000,000 |
| Shuang, Hai-liang | SP | Nashville Outlaws | 18 | 07/19/2024 | Linjiang | CHN | Right | Left | 6' 1" | 180 lbs | - |
| Sidebottom, Marvin | RP | Panama City Piranhas | 30 | 09/09/2012 | Belmopan | BLZ | Right | Right | 6' 7" | 235 lbs | $2,200,000 |
| Silva, Ángel | SP | Toledo Stingers | 29 | 01/11/2013 | Santo Domingo | DOM | Left | Left | 5' 10" | 185 lbs | $2,100,000 |
| Simon, Carlos | SP | Nashville Outlaws | 30 | 11/13/2012 | Fresno | USA | Right | Right | 6' 3" | 210 lbs | $280,000 |
| Sinclair, Max | RF | Pittsburgh Kingfishers | 23 | 02/21/2019 | North Canton | USA | Left | Left | 6' 1" | 175 lbs | $280,000 |
| Sison, Jim | RP | Montana Pandas | 35 | 05/15/2007 | Manton | USA | Right | Right | 6' 1" | 220 lbs | $750,000 |
| Skipworth, Ray | RP | Vancouver Grey Wolves | 36 | 04/12/2006 | Milford | USA | Right | Right | 6' 2" | 220 lbs | $675,000 |
| Slaybaugh, Jason | 1B | Seattle Rocketeers | 30 | 11/10/2012 | Austin | USA | Right | Right | 6' 2" | 215 lbs | $11,300,000 |
| Smith, Dan | RP | Athletic Club KC | 25 | 08/21/2017 | Abilene | USA | Right | Right | 6' 1" | 205 lbs | $280,000 |
| So, Jun-hun | LF | Vancouver Grey Wolves | 17 | 05/18/2025 | Incheon | KOR | Switch | Left | 6' 0" | 175 lbs | - |
| Solís, Javier | RP | Pittsburgh Kingfishers | 23 | 03/28/2019 | San Miguel Chicaj | GUA | Switch | Right | 6' 4" | 195 lbs | $280,000 |
| Solís, Rubén | CF | Oakland Oaks | 18 | 08/19/2024 | Santiago | DOM | Switch | Right | 6' 1" | 170 lbs | - |
| Son, Kyung-chul | CF | Pittsburgh Kingfishers | 18 | 12/03/2024 | Seoul | KOR | Left | Right | 6' 0" | 160 lbs | - |
| Soto, Bartolo | RF | Nashville Outlaws | 33 | 09/07/2009 | Puerto Plata | DOM | Left | Left | 6' 2" | 235 lbs | $6,500,000 |
| Stanley, Forest | SP | Nashville Outlaws | 32 | 06/27/2010 | Bartlesville | USA | Switch | Right | 6' 3" | 225 lbs | $7,550,000 |
| Starr, Barney | RP | Panama City Piranhas | 36 | 01/28/2006 | Green Bay | USA | Right | Right | 6' 2" | 240 lbs | $2,900,000 |
| Steele, Morton | RP | Montana Pandas | 32 | 09/04/2010 | Carmichael | USA | Left | Right | 6' 4" | 235 lbs | $280,000 |
| Stinson, Tim | C | Brooklyn Dodgers | 34 | 03/29/2008 | Presidential Lakes Estates | USA | Left | Right | 6' 0" | 245 lbs | $7,000,000 |
| Stone, David | SS | Vancouver Grey Wolves | 28 | 10/16/2014 | Chicago | USA | Right | Right | 6' 2" | 185 lbs | $650,000 |
| Studdard, Antoine | 2B | Panama City Piranhas | 28 | 12/17/2014 | Newark | USA | Left | Right | 6' 0" | 200 lbs | $280,000 |
| Studer, Radomir | 3B | Brooklyn Dodgers | 16 | 05/15/2026 | Sumperk | CZE | Right | Right | 5' 9" | 155 lbs | - |
| Suárez, Rafael | C | Panama City Piranhas | 17 | 02/23/2025 | Cotuí | DOM | Right | Right | 6' 0" | 185 lbs | - |
| Sugimoto, Yoriyoshi | CL | Toledo Stingers | 35 | 02/26/2007 | Yokohama | JPN | Right | Right | 5' 10" | 205 lbs | $11,500,000 |
| Swanton, Clive | CF | Oakland Oaks | 18 | 12/23/2024 | Kingston | JAM | Right | Right | 6' 4" | 175 lbs | - |
| Sweemey, Onson | RP | Echo Park Lakers | 33 | 05/09/2009 | Perris | USA | Left | Left | 6' 6" | 230 lbs | $4,300,000 |
| Szema, Ming-an | 1B | Long Island Lighthouse | 18 | 01/06/2024 | Putai | TPE | Right | Right | 6' 0" | 190 lbs | - |
