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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | HR | YEAR | Open Season Leaderboard |
|---|---|---|---|---|
| 1 | Ramón Padilla# | 68 | 2035-2042 | |
| 2 | Hank Wilder | 59 | 2019-2032 | |
| 3 | Dave King | 57 | 2014-2026 | |
| 4 | José Corona | 51 | 2028-2040 | |
| 5 | Gonzalo López* | 41 | 2015-2023 | |
| 6 | Carlos Maldonado | 40 | 2025-2032 | |
| 7 | Fernando López | 38 | 2014-2020 | |
| 7 | Martín Martínez | 38 | 2023-2029 | |
| 9 | Ed Anderson | 35 | 2016-2025 | |
| 10 | Augusto Encarnación | 34 | 2029-2040 | |
| 11 | Jaime Soto# | 29 | 2038-2041 | |
| 12 | Colm Goodwill# | 27 | 2032-2042 | |
| 13 | Francisco Alhama# | 26 | 2040-2042 | |
| 13 | Felipe Campos | 26 | 2031-2040 | |
| 13 | Tomás Gonzáles | 26 | 2014-2019 | |
| 13 | Wilfred McLaughlin* | 26 | 2018-2033 | |
| 17 | Ricardo Cruz | 25 | 2014-2021 | |
| 17 | Chris Etheridge | 25 | 2026-2034 | |
| 19 | Richard Jost# | 24 | 2029-2042 | |
| 19 | Jason Nicholson | 24 | 2014-2017 | |
| 19 | Ben Ramey | 24 | 2014-2015 | |
| 19 | Greg Robinson | 24 | 2017-2025 | |
| 19 | Barsati Saraf# | 24 | 2038-2042 | |
| 19 | Kent Summey | 24 | 2029-2038 | |
| 25 | Wes Bradley | 23 | 2021-2027 | |
| 25 | Rio Mence# | 23 | 2033-2041 | |
| 27 | Manuel Ramos# | 22 | 2033-2042 | |
| 28 | Amon-Ra St. Brown# | 21 | 2032-2042 | |
| 29 | Armando Alvarado | 20 | 2022-2036 | |
| 29 | Guillermo Montoya | 20 | 2015-2022 | |
| 31 | Mark O'Monaghan | 19 | 2018-2021 | |
| 31 | Todd Schenkel | 19 | 2018-2022 | |
| 31 | Tyrone Scott | 19 | 2016-2025 | |
| 31 | Ronald Shelton | 19 | 2015-2022 | |
| 31 | Tom Smith | 19 | 2014-2017 | |
| 31 | Ethan Stanford | 19 | 2025-2032 | |
| 31 | Mike Strickland | 19 | 2030-2037 | |
| 38 | Gustavo Fuentes | 18 | 2020-2024 | |
| 38 | Harlan Price | 18 | 2015-2019 | |
| 40 | Harry Fuller | 17 | 2014-2025 | |
| 40 | Félix Rodríguez | 17 | 2017-2020 | |
| 40 | Lawrence Washington | 17 | 2015-2025 | |
| 43 | Arnold Griffith | 16 | 2015-2026 | |
| 44 | Kumanosuke Abe | 15 | 2022-2031 | |
| 44 | Jesús Cabañe | 15 | 2022-2030 | |
| 44 | Cristián Coronado | 15 | 2034-2037 | |
| 47 | Ik-jun Cho# | 14 | 2039-2041 | |
| 47 | Robby Day | 14 | 2021-2034 | |
| 47 | Elian Gonzalez | 14 | 2030-2034 | |
| 47 | Esteban León# | 14 | 2038-2042 | |
| 47 | José Santos# | 14 | 2034-2042 | |
| 47 | Bill Taylor | 14 | 2015-2023 | |
| 53 | Khal Drogo | 13 | 2030-2042 | |
| 53 | Anthony Johnston | 13 | 2020-2029 | |
| 53 | Lúcio Montoya | 13 | 2017-2022 | |
| 56 | Carlos Campos# | 12 | 2032-2036 | |
| 56 | Brit Davis# | 12 | 2035-2040 | |
| 56 | Henrique de Senna Fernandes# | 12 | 2033-2042 | |
| 56 | Rafael Durango | 12 | 2023-2028 | |
| 56 | Sadakuno Hashimoto | 12 | 2037-2040 | |
| 56 | Onye Mahusay | 12 | 2034-2037 | |
| 56 | Hirohisa Ogasawara | 12 | 2031-2037 | |
| 56 | Jeb Sexton | 12 | 2031-2037 | |
| 64 | Randy Bowen | 11 | 2019-2028 | |
| 64 | Pedro Cruz | 11 | 2016-2023 | |
| 64 | Pedro Gómez | 11 | 2024-2029 | |
| 64 | Tim Robinson | 11 | 2019-2024 | |
| 64 | Joe Shaw | 11 | 2017-2019 | |
| 64 | Jack Weber | 11 | 2015-2023 | |
| 70 | Gil Andersen# | 10 | 2035-2042 | |
| 70 | Pedro Corona | 10 | 2028-2035 | |
| 70 | Lonnie Doble# | 10 | 2041-2042 | |
| 70 | Richard Edwards# | 10 | 2038-2042 | |
| 70 | Ellis Greenham | 10 | 2031-2038 | |
| 70 | Júlio Rodríguez# | 10 | 2033-2039 | |
| 70 | Luis Rodríguez# | 10 | 2040-2041 | |
| 77 | Tom Christensen | 9 | 2021-2023 | |
| 77 | Joe Ferneyhough | 9 | 2015-2018 | |
| 77 | Sergio Martínez | 9 | 2024-2031 | |
| 77 | Travis Newsome | 9 | 2020-2032 | |
| 77 | Danny Spencer | 9 | 2014-2017 | |
| 77 | Bren Spillane# | 9 | 2036-2042 | |
| 77 | José Torres# | 9 | 2033-2042 | |
| 77 | Nuygen Vuong | 9 | 2031-2038 | |
| 85 | Terry Armstrong | 8 | 2020-2029 | |
| 85 | Bill Becker | 8 | 2015-2019 | |
| 85 | Nick Boyd | 8 | 2029-2041 | |
| 85 | Mike Burns | 8 | 2022-2032 | |
| 85 | Pedro Cruz | 8 | 2017-2022 | |
| 85 | Cristo González | 8 | 2023-2031 | |
| 85 | Rod Jones | 8 | 2019-2026 | |
| 85 | Lester Kwiatkowski# | 8 | 2032-2039 | |
| 85 | Carlos Martínez# | 8 | 2039-2041 | |
| 85 | Krystof Melichar# | 8 | 2035-2041 | |
| 85 | Xavier Vásquez | 8 | 2025-2031 | |
| 96 | Mike Blue | 7 | 2016-2023 | |
| 96 | James Bolden | 7 | 2014-2015 | |
| 96 | Sal Bradshaw | 7 | 2027-2032 | |
| 96 | Ramón Garmendia# | 7 | 2030-2042 | |
| 96 | Tony Hernández# | 7 | 2039-2042 |
