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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | HR | YEAR | Open Season Leaderboard |
|---|---|---|---|---|
| 1 | Mario Ramos | 312 | 2022-2041 | |
| 2 | Steve Ingram | 277 | 2014-2029 | |
| 3 | Javier Sánchez# | 220 | 2023-2042 | |
| 4 | Bart Lewis | 195 | 2019-2036 | |
| 5 | Sébastien Cornu# | 193 | 2035-2042 | |
| 6 | Emílio Sáenz | 178 | 2014-2025 | |
| 7 | Kevin Howard | 174 | 2014-2021 | |
| 7 | Mike Silver* | 174 | 2014-2027 | |
| 9 | Michael Neely | 173 | 2016-2029 | |
| 9 | Jesús Vargas# | 173 | 2029-2042 | |
| 11 | Jesús Encarnación# | 156 | 2038-2042 | |
| 12 | Yao-pang Chiang# | 153 | 2031-2042 | |
| 13 | Manuel Romo | 152 | 2014-2020 | |
| 14 | Obidiah Lewis# | 148 | 2028-2041 | |
| 15 | Don Brown* | 143 | 2014-2018 | |
| 16 | Hugh Mungus# | 141 | 2027-2042 | |
| 17 | Nathan Tanner | 139 | 2024-2038 | |
| 18 | Palaie Gaoteote# | 135 | 2034-2042 | |
| 19 | Luis Muńóz | 134 | 2019-2025 | |
| 20 | Derek Bangert | 133 | 2031-2041 | |
| 21 | Dewitt Hopper# | 128 | 2028-2041 | |
| 21 | Javier Sierra# | 128 | 2036-2042 | |
| 23 | Marcus Shill# | 127 | 2035-2042 | |
| 24 | David Smith | 126 | 2018-2034 | |
| 25 | Kenny Webster | 124 | 2021-2037 | |
| 26 | Jorge Herrera# | 122 | 2035-2042 | |
| 26 | Pedro Vázquez | 122 | 2025-2036 | |
| 28 | Hank Wilder | 118 | 2019-2032 | |
| 29 | Bob Dickerson | 115 | 2019-2037 | |
| 30 | Earl Ellis | 114 | 2015-2021 | |
| 31 | Herman Hayes | 112 | 2016-2029 | |
| 32 | Ryan Westlake | 111 | 2019-2030 | |
| 33 | Pedro Santos | 109 | 2022-2034 | |
| 34 | Daniel McCoy# | 107 | 2032-2042 | |
| 34 | Jason Slaybaugh# | 107 | 2034-2041 | |
| 36 | Neil Lawson | 105 | 2017-2031 | |
| 37 | Jon Osterman# | 104 | 2028-2042 | |
| 37 | Manoo Satyavrat# | 104 | 2029-2041 | |
| 39 | Carlos Ortega | 103 | 2018-2025 | |
| 39 | Jesús Reyes | 103 | 2023-2032 | |
| 39 | Roberto Sánchez | 103 | 2026-2037 | |
| 42 | Count Dante# | 102 | 2025-2042 | |
| 42 | Chris Smith | 102 | 2014-2025 | |
| 44 | Stefano Gaddi | 101 | 2023-2032 | |
| 44 | Zahid Kashani# | 101 | 2032-2041 | |
| 46 | Júlio Maldonado | 100 | 2020-2025 | |
| 46 | Chris Rice | 100 | 2015-2026 | |
| 48 | Tsai Ng | 97 | 2030-2039 | |
| 49 | Carlos Padilla | 96 | 2024-2036 | |
| 50 | Yannick Hendriksen | 95 | 2022-2035 | |
| 50 | Vicente Martínez | 95 | 2015-2020 | |
| 52 | António Martínez | 94 | 2024-2035 | |
| 52 | David Verhoeve | 94 | 2018-2024 | |
| 54 | Ramiro Salazar | 92 | 2016-2027 | |
| 55 | Kolby Hay# | 91 | 2039-2042 | |
| 55 | Alfredo Martínez | 91 | 2025-2040 | |
| 57 | José Corona | 90 | 2028-2040 | |
| 58 | Mal Wadley | 89 | 2017-2028 | |
| 59 | Enrique Pérez* | 88 | 2018-2029 | |
| 60 | Ramón Souza | 87 | 2015-2027 | |
| 60 | Tadayoshi Watanabe# | 87 | 2032-2041 | |
| 62 | Aukukero Mincarlie | 86 | 2014-2017 | |
| 62 | Shiki Sanu# | 86 | 2030-2042 | |
| 62 | Jerry Yates# | 86 | 2031-2041 | |
| 65 | Gabriel Pérez | 84 | 2023-2034 | |
| 66 | Tom Burton | 83 | 2036-2041 | |
| 67 | Eduardo Alvarado | 82 | 2015-2020 | |
| 67 | Félix López | 82 | 2021-2033 | |
| 67 | Marcos Zúńiga | 82 | 2014-2022 | |
| 70 | Anselmo Berneu# | 81 | 2031-2042 | |
| 70 | Dylan Carson | 81 | 2028-2040 | |
| 72 | Yu-zeng Si | 80 | 2032-2041 | |
| 72 | Qing-nian Zexian# | 80 | 2038-2041 | |
| 74 | Gilberto Juárez | 79 | 2028-2039 | |
| 75 | Spencer Powell# | 78 | 2034-2042 | |
| 76 | Lupo Cotto | 76 | 2027-2041 | |
| 76 | David Henderson | 76 | 2016-2025 | |
| 78 | Wilbur Davis | 75 | 2027-2040 | |
| 78 | Carlos Rodríguez | 75 | 2022-2033 | |
| 78 | Salvador Trevino | 75 | 2028-2037 | |
| 81 | Edwin Church | 74 | 2020-2034 | |
| 81 | Ramón Gómez | 74 | 2021-2031 | |
| 83 | Rick Mayfield | 73 | 2027-2035 | |
| 83 | Martín Talia# | 73 | 2034-2042 | |
| 85 | Billy Dotson# | 72 | 2030-2042 | |
| 85 | Scott Kerin# | 72 | 2029-2042 | |
| 85 | Iván Vega | 72 | 2023-2038 | |
| 88 | Dean Jackson# | 71 | 2038-2040 | |
| 89 | Ken Norman | 70 | 2015-2021 | |
| 90 | John Downing* | 69 | 2014-2034 | |
| 90 | Juan González | 69 | 2022-2025 | |
| 90 | Tae-cho Han# | 69 | 2033-2042 | |
| 93 | SaQwan Hackett | 68 | 2028-2036 | |
| 93 | Ramón Padilla# | 68 | 2035-2042 | |
| 93 | José Carlos Pérez | 68 | 2027-2039 | |
| 96 | Eiji Suzuki | 67 | 2017-2023 | |
| 96 | Jonas van Claveren# | 67 | 2036-2042 | |
| 98 | Daniel Lallanilla | 66 | 2015-2022 | |
| 98 | Tomás Martínez | 66 | 2031-2036 | |
| 98 | Gabriel Montoya# | 66 | 2037-2041 |
