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| Name | Pos | Team | Age | DOB | POB | Nationality | Bats | Throws | Height | Weight | Salary |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Sa, Hyeon-uk | RP | Akron Blimps | 25 | 08/12/2016 | Sangju | KOR | Left | Right | 6' 3" | 195 lbs | - |
| Sáenz, Roberto | RP | Olympia Ogres | 23 | 03/29/2018 | Río Segundo | CRC | Left | Left | 5' 11" | 160 lbs | - |
| Sánchez, Ramón | RP | Akron Blimps | 24 | 03/09/2017 | Lake Los Angeles | USA | Right | Left | 5' 10" | 170 lbs | - |
| Sanders, Jason | RP | Ithaca Fighting Imps | 29 | 12/12/2012 | Prichard | USA | Right | Right | 6' 2" | 220 lbs | - |
| Santos, José | RP | Virginia Palladium Sox | 27 | 07/13/2014 | Los Angeles | USA | Left | Left | 6' 1" | 210 lbs | - |
| Santos, Pedro | RF | Chesapeake Continentals | 23 | 07/03/2018 | Ft. Worth | USA | Right | Right | 6' 2" | 195 lbs | - |
| Sarkies, Rod | 1B | Crescent City Krewe | 24 | 06/27/2017 | Canberra | AUS | Right | Right | 6' 3" | 215 lbs | $280,000 |
| Savinon, Pepe | LF | Olympia Ogres | 20 | 05/11/2021 | Culiacan | MEX | Right | Right | 6' 1" | 180 lbs | - |
| Schalk, Norbert | 2B | Crescent City Krewe | 21 | 06/01/2020 | Willemstad | CUR | Right | Right | 6' 0" | 170 lbs | - |
| Seals, Albert | LF | Crescent City Krewe | 28 | 05/28/2013 | Coral Springs | USA | Right | Right | 6' 1" | 215 lbs | - |
| Semprún, Carlos | SP | Springfield Shooters | 21 | 03/04/2020 | Santo Domingo | DOM | Left | Left | 6' 4" | 200 lbs | - |
| Setiadji, Koswara | RP | Westwood Sixshooters | 27 | 09/17/2014 | Doka | SUD | Switch | Right | 6' 6" | 225 lbs | - |
| Shaw, Wiley | RP | Akron Blimps | 27 | 03/24/2014 | Middletown | USA | Right | Right | 6' 0" | 200 lbs | - |
| Shiu, Xie-li | 2B | Virginia Palladium Sox | 22 | 08/09/2019 | Taichung | TPE | Left | Right | 6' 1" | 190 lbs | - |
| Siddall, John | 3B | Westwood Sixshooters | 25 | 05/22/2016 | Brampton | CAN | Right | Right | 6' 4" | 210 lbs | - |
| Silva, Armando | CF | Virginia Palladium Sox | 25 | 03/24/2016 | Santo Domingo | DOM | Right | Right | 5' 11" | 190 lbs | - |
| Sloan, Clarence | C | Akron Blimps | 22 | 07/11/2019 | Tampa | USA | Right | Right | 6' 0" | 200 lbs | - |
| Smith, Adam | SS | Mercer Island Screaming Eagles | 26 | 12/24/2015 | Toledo | USA | Right | Right | 6' 0" | 200 lbs | - |
| Smith, Jeffery | CF | Olympia Ogres | 22 | 08/03/2019 | Los Angeles | USA | Left | Left | 6' 0" | 190 lbs | - |
| Solís, Jesús | RP | Ithaca Fighting Imps | 27 | 07/29/2014 | Valencia | VEN | Right | Right | 6' 6" | 215 lbs | - |
| Soriano, José | CF | Crescent City Krewe | 27 | 05/11/2014 | Palos Heights | USA | Left | Left | 6' 1" | 195 lbs | $280,000 |
| Soung, Sang-yeon | RP | Biloxi Shuckers | 23 | 01/25/2018 | Suji | KOR | Right | Right | 5' 9" | 170 lbs | - |
| Stanley, Carter | 1B | Biloxi Shuckers | 21 | 11/16/2020 | Tamalpais-Homestead Valley | USA | Left | Left | 6' 6" | 235 lbs | - |
| Stark, Paul | 2B | Olympia Ogres | 22 | 01/07/2019 | Schaumburg | USA | Right | Right | 6' 3" | 180 lbs | - |
| Stavely, Dylan | CF | Springfield Shooters | 20 | 06/17/2021 | Charlotte Amalie | VIR | Right | Right | 6' 2" | 170 lbs | - |
| Stevens, Martin | CF | Crescent City Krewe | 24 | 01/05/2017 | Ft. Morgan | USA | Right | Right | 6' 1" | 195 lbs | - |
| Strickland, James | SS | Crescent City Krewe | 27 | 04/05/2014 | Washington | USA | Right | Right | 6' 3" | 195 lbs | - |
| Subramanya, Cakaraka | RP | Chesapeake Continentals | 24 | 01/13/2017 | Koyampattur | IND | Switch | Right | 6' 5" | 190 lbs | - |
| Summers, Dave | RF | Crescent City Krewe | 25 | 08/18/2016 | Dearborn Heights | USA | Left | Left | 6' 0" | 195 lbs | - |
| Summers, Hunter | SP | Springfield Shooters | 25 | 06/28/2016 | New York | USA | Switch | Right | 6' 6" | 230 lbs | - |
