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| Name | Pos | Team | Age | DOB | POB | Nationality | Bats | Throws | Height | Weight | Salary |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Salas, Bill | SP | Kingston Mangos | 23 | 06/23/2018 | Santa Ana | USA | Left | Left | 6' 3" | 215 lbs | - |
| Salmi, Aatos | SS | Laredo Hawks | 22 | 12/22/2019 | Kiskorös | HUN | Right | Right | 6' 2" | 175 lbs | - |
| Sánchez, Nelson | 2B | Niagara Falls Expos | 19 | 10/31/2022 | San Mateo | VEN | Right | Right | 6' 2" | 195 lbs | - |
| Sánchez, Vicente | RP | Niagara Falls Expos | 22 | 12/03/2019 | Tucuman | ARG | Right | Right | 6' 4" | 190 lbs | - |
| Savage, John | RP | Mancelona Torch | 22 | 09/02/2019 | Corpus Christi | USA | Right | Right | 6' 4" | 210 lbs | - |
| Schock, Justin | 3B | Delaware 1787 BC | 21 | 06/21/2020 | Palm Bay | USA | Right | Right | 6' 3" | 190 lbs | - |
| Scott, Jerry | CF | Delaware 1787 BC | 23 | 01/25/2018 | Elizabethtown | USA | Right | Right | 6' 2" | 195 lbs | - |
| Selemani, Yaw | SP | Niagara Falls Expos | 20 | 11/30/2021 | Benoni | RSA | Right | Right | 6' 1" | 180 lbs | - |
| Shallcross, Nathan | CF | Syracuse Storm | 21 | 04/17/2020 | New York | USA | Left | Left | 6' 1" | 180 lbs | - |
| Shen, Qi-zhen | 1B | Mancelona Torch | 22 | 07/29/2019 | Kangshan | TPE | Left | Right | 6' 1" | 200 lbs | - |
| Shu, Huang-di | 3B | Grim Reapers | 22 | 10/30/2019 | Tachi | TPE | Switch | Right | 5' 10" | 180 lbs | - |
| Sims, Nick | C | Washington Generals | 21 | 12/09/2020 | Hackensack | USA | Right | Right | 6' 2" | 205 lbs | - |
| Sin, Jun-suk | SP | Niagara Falls Expos | 19 | 11/27/2022 | Seoul | KOR | Right | Right | 6' 2" | 180 lbs | - |
| Smith, Jon | RP | Delaware 1787 BC | 22 | 06/13/2019 | Monroe | USA | Right | Left | 6' 2" | 195 lbs | - |
| Smith, Mark | SP | Mancelona Torch | 22 | 11/06/2019 | Queens | USA | Right | Right | 6' 2" | 205 lbs | - |
| Sprinkle, Andrew | 3B | Myrtle Beach Seahawks | 21 | 04/14/2020 | New Orleans | USA | Right | Right | 6' 1" | 185 lbs | - |
| Steele, Willie | RP | Kingston Mangos | 21 | 06/09/2020 | Denver | USA | Left | Right | 6' 0" | 185 lbs | - |
| Steur, Vaclav | 1B | Kingston Mangos | 21 | 12/23/2020 | Oranjestad | ARU | Right | Right | 6' 6" | 225 lbs | - |
| Stewart, Tom | SP | Grim Reapers | 22 | 09/07/2019 | Sandusky | USA | Switch | Right | 6' 3" | 205 lbs | - |
| Stinson, Keith | RP | Kingston Mangos | 21 | 12/21/2020 | Suncook | USA | Switch | Left | 6' 3" | 205 lbs | - |
| Stockhill, Glen | CF | Mancelona Torch | 22 | 07/01/2019 | London | ENG | Right | Right | 6' 0" | 180 lbs | - |
| Suárez, Roberto | C | Washington Generals | 21 | 04/13/2020 | Buenos Aires | ARG | Right | Right | 6' 4" | 225 lbs | - |
| Sullivan, Geoff | 2B | Laredo Hawks | 22 | 11/16/2019 | Madison Heights | USA | Right | Right | 6' 1" | 185 lbs | - |
| Sykes, Paul | 2B | Mancelona Torch | 21 | 05/02/2020 | Coventry | ENG | Right | Right | 6' 2" | 190 lbs | - |
