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| Name | Pos | Team | Age | DOB | POB | Nationality | Bats | Throws | Height | Weight | Salary |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Sa, Hyeon-uk | SP | Akron Blimps | 24 | 08/12/2016 | Sangju | KOR | Left | Right | 6' 3" | 195 lbs | - |
| Saavedra, Pablo | SS | Lancaster Farmers | 23 | 02/16/2017 | Santo Domingo | DOM | Right | Right | 6' 2" | 190 lbs | - |
| San Martín, Sergio | SS | Virginia Beach Whales | 28 | 09/25/2012 | Bedford | USA | Right | Right | 5' 9" | 190 lbs | - |
| Sánchez, Adrián | C | Durham Rapiers | 27 | 12/15/2013 | Terrytown | USA | Right | Right | 5' 11" | 220 lbs | - |
| Sánchez, Ramón | RP | Akron Blimps | 23 | 03/09/2017 | Lake Los Angeles | USA | Right | Left | 5' 10" | 165 lbs | - |
| Sanders, Paul | SS | Minnesota Loons | 22 | 07/27/2018 | Hollandale | USA | Right | Right | 6' 2" | 185 lbs | - |
| Sandoval, León | 1B | Yakima Hops | 25 | 03/02/2015 | Santiago | CHI | Left | Left | 6' 2" | 215 lbs | - |
| Santos, Juan | RP | Lancaster Farmers | 23 | 01/28/2017 | Santo Domingo | DOM | Right | Right | 6' 3" | 190 lbs | - |
| Scanlan, Oakland | RP | Akron Blimps | 26 | 06/08/2014 | Salem | USA | Right | Right | 6' 8" | 245 lbs | - |
| Schrattenthaler, David | SP | Lancaster Farmers | 21 | 02/02/2019 | Robbinsdale | USA | Switch | Right | 6' 0" | 175 lbs | - |
| Scott, Jerry | CF | Atlantic City Sonics | 22 | 01/25/2018 | Elizabethtown | USA | Right | Right | 6' 2" | 190 lbs | - |
| Scribbner, Thom | 2B | Casper Ghosts | 24 | 11/21/2016 | Santa Cruz | USA | Right | Right | 6' 2" | 205 lbs | - |
| Shaw, Wiley | RP | Akron Blimps | 26 | 03/24/2014 | Middletown | USA | Right | Right | 6' 0" | 190 lbs | - |
| Shepard, Dave | SP | Casper Ghosts | 27 | 06/08/2013 | Millcreek | USA | Left | Left | 6' 2" | 195 lbs | - |
| Shi, Pao-tzu | SP | Minnesota Loons | 26 | 09/07/2014 | Harbin | CHN | Right | Left | 5' 11" | 185 lbs | - |
| Siddall, John | CF | Biloxi Shuckers | 24 | 05/22/2016 | Brampton | CAN | Right | Right | 6' 4" | 210 lbs | - |
| Silva, Miguel | C | Biloxi Shuckers | 25 | 09/08/2015 | Manicaragua | CUB | Right | Right | 6' 1" | 215 lbs | - |
| Smith, Joe | RP | Minnesota Loons | 24 | 10/15/2016 | San Francisco | USA | Left | Left | 6' 1" | 185 lbs | - |
| Smith, Robert | SP | Atlantic City Sonics | 27 | 04/02/2013 | New York | USA | Right | Right | 5' 11" | 195 lbs | - |
| Smith, Tim | RP | Lancaster Farmers | 23 | 03/17/2017 | Hiram | USA | Right | Right | 6' 0" | 190 lbs | - |
| Soisalo, Pellervo | SP | Durham Rapiers | 27 | 10/16/2013 | Komadi | HUN | Left | Left | 6' 4" | 200 lbs | - |
| Solleveld, Olaf | RP | Virginia Beach Whales | 28 | 12/27/2012 | Barber | CUR | Right | Right | 6' 4" | 220 lbs | - |
| Sorensen, Marty | RP | Lancaster Farmers | 23 | 03/05/2017 | Wanganui | NZL | Right | Right | 6' 6" | 210 lbs | - |
| Souza, Jorge | SP | Lancaster Farmers | 20 | 09/01/2020 | Villa Vazquez | DOM | Right | Right | 6' 1" | 175 lbs | - |
| Souza, Júlio | CF | Minnesota Loons | 23 | 11/07/2017 | Vicente Noble | DOM | Left | Left | 6' 1" | 175 lbs | - |
| Speranza, Paolo | RP | Biloxi Shuckers | 24 | 10/30/2016 | Valencia | VEN | Switch | Left | 5' 10" | 175 lbs | - |
| Srivastav, Abhipala | CF | Atlantic City Sonics | 23 | 05/08/2017 | Rohtak | IND | Right | Right | 6' 3" | 180 lbs | - |
| Stanley, José | RP | Biloxi Shuckers | 24 | 05/11/2016 | Corvallis | USA | Right | Right | 6' 11" | 260 lbs | - |
| Sterling, Raheem | 1B | Free Agent | 26 | 03/14/2014 | Kingston | JAM | Right | Right | 6' 2" | 215 lbs | - |
| Stevens, John | RP | Virginia Beach Whales | 21 | 04/15/2019 | Porcupine | CAN | Right | Right | 6' 0" | 190 lbs | - |
| Strachota, Todd | RF | Lancaster Farmers | 24 | 11/03/2016 | St. Paul Park | USA | Left | Left | 6' 3" | 220 lbs | - |
| Sutkamp, Arnold | RP | Durham Rapiers | 25 | 08/27/2015 | Dantumadeel | NED | Right | Right | 6' 2" | 190 lbs | - |
