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| Name | Pos | Team | Age | DOB | POB | Nationality | Bats | Throws | Height | Weight | Salary |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Sakei, Masahiro | SP | Panama City Piranhas | 33 | 08/17/2007 | Futtsu | JPN | Switch | Right | 6' 6" | 220 lbs | $700,000 |
| Salcido, Carlos | RP | Panama City Piranhas | 30 | 09/23/2010 | El Cercado | DOM | Right | Right | 5' 10" | 165 lbs | $800,000 |
| Salinas, José | 3B | Echo Park Lakers | 29 | 08/23/2011 | Indianapolis | USA | Right | Right | 6' 0" | 200 lbs | $370,000 |
| Salt, Jack | RP | Kingston Township Knights | 29 | 03/29/2011 | Manassas | USA | Right | Right | 6' 4" | 215 lbs | $700,000 |
| Sánchez, Arturo | SP | Toledo Stingers | 18 | 10/27/2022 | Chilibre | PAN | Right | Right | 6' 2" | 175 lbs | - |
| Sánchez, Arturo | SP | Mississippi Mockingbirds | 19 | 10/23/2021 | Manizales | COL | Right | Right | 6' 2" | 185 lbs | - |
| Sandaele, Tim | RP | Toledo Stingers | 32 | 12/13/2008 | Fargo | USA | Right | Right | 5' 10" | 205 lbs | $360,000 |
| Sandoval, Fernando | SP | Toledo Stingers | 18 | 03/12/2022 | Turrialba | CRC | Right | Right | 6' 2" | 175 lbs | - |
| Santegoeds, Buddy | SP | Toledo Stingers | 17 | 03/16/2023 | Princess Quarter | SIM | Right | Right | 6' 1" | 175 lbs | - |
| Santos, José | SS | Panama City Piranhas | 16 | 01/01/2024 | Santo Domingo | DOM | Switch | Right | 6' 1" | 160 lbs | - |
| Santos, José | SS | Montana Pandas | 31 | 06/17/2009 | Carora | VEN | Right | Right | 6' 2" | 215 lbs | $760,000 |
| Sanu, Shiki | 3B | Toledo Stingers | 33 | 05/29/2007 | Sapporo | JPN | Switch | Right | 6' 1" | 210 lbs | $5,500,000 |
| Saracho, Jaicus | CF | Kingston Township Knights | 16 | 02/28/2024 | Malasila | PHI | Right | Right | 6' 2" | 170 lbs | - |
| Sardinha, Guaspar | C | D.C. Divided | 17 | 09/19/2023 | Carapicuíba | BRA | Right | Right | 6' 6" | 205 lbs | - |
| Sasaki, Yoshida | SP | Panama City Piranhas | 18 | 03/30/2022 | Matsue | JPN | Right | Left | 5' 11" | 170 lbs | - |
| Sauls, José | RP | Free Agent | 34 | 07/29/2006 | Rocklin | USA | Left | Right | 5' 9" | 200 lbs | - |
| Schaefer, John | LF | Echo Park Lakers | 32 | 03/19/2008 | Cincinnati | USA | Left | Left | 6' 2" | 240 lbs | $3,400,000 |
| Schreibvogel, Joe | 1B | Echo Park Lakers | 23 | 10/05/2017 | Garden City | USA | Left | Right | 6' 2" | 230 lbs | $280,000 |
| Schuilenberg, Kasper | C | Seattle Rocketeers | 32 | 09/14/2008 | Cole Bay | SIM | Right | Right | 6' 1" | 225 lbs | $280,000 |
| Scruggins, Carsello | RF | Panama City Piranhas | 26 | 07/18/2014 | Halawa | USA | Right | Right | 6' 1" | 205 lbs | $280,000 |
| Seco, Javier | 1B | Free Agent | 26 | 08/01/2014 | Changuinola | PAN | Left | Left | 6' 3" | 225 lbs | - |
| Seitzinger, Wilfried | 2B | Panama City Piranhas | 19 | 08/25/2021 | Rincon | ANT | Left | Right | 6' 3" | 185 lbs | - |
| Sellers, Ricky | SP | Toledo Stingers | 25 | 01/28/2015 | Oro Valley | USA | Switch | Right | 6' 0" | 185 lbs | $280,000 |
| Serano, Pedro | 1B | Toledo Stingers | 26 | 05/13/2014 | Prairie Village | USA | Left | Left | 6' 6" | 250 lbs | $280,000 |
| Sherman, Phil | C | Brooklyn Dodgers | 34 | 10/09/2006 | Claverack-Red Mills | USA | Right | Right | 6' 0" | 225 lbs | $1,250,000 |
| Shibutani, Hidehira | SP | Montana Pandas | 17 | 12/29/2023 | Sendai | JPN | Right | Right | 6' 0" | 170 lbs | - |
| Shmerkin, Yaakov | LF | Seattle Rocketeers | 25 | 01/20/2015 | Arara-BaNegev | ISR | Right | Right | 5' 10" | 180 lbs | $280,000 |
| Sidebottom, Marvin | RP | Panama City Piranhas | 28 | 09/09/2012 | Belmopan | BLZ | Right | Right | 6' 7" | 230 lbs | $2,200,000 |
| Silva, Ángel | SP | Toledo Stingers | 27 | 01/11/2013 | Santo Domingo | DOM | Left | Left | 5' 10" | 185 lbs | $1,410,000 |
| Sims, Chase | SP | Kingston Township Knights | 24 | 02/23/2016 | Baton Rouge | USA | Right | Left | 6' 0" | 185 lbs | $4,000,000 |
| Sipe, José | RP | Houston 1837 BBC | 31 | 03/21/2009 | Lebanon | USA | Switch | Left | 6' 5" | 225 lbs | $280,000 |
| Smith, Adam | 1B | Houston 1837 BBC | 25 | 03/22/2015 | Haddington | SCO | Right | Right | 6' 1" | 190 lbs | $280,000 |
| Smith, Millard | RP | Houston 1837 BBC | 27 | 09/28/2013 | Albuquerque | USA | Switch | Right | 5' 11" | 190 lbs | $420,000 |
| Snider, Dale | RP | Kingston Township Knights | 30 | 02/21/2010 | Ridgefield Park | USA | Left | Left | 6' 6" | 235 lbs | $700,000 |
| Solís, Juan Carlos | C | Echo Park Lakers | 19 | 05/17/2021 | La Chorrera | PAN | Right | Right | 6' 2" | 185 lbs | - |
| Soto, Jaime | 2B | St. Louis Coeur | 25 | 12/20/2015 | Santiago | CHI | Right | Right | 6' 1" | 195 lbs | $280,000 |
| Sperber, Murray | RF | Montana Pandas | 29 | 04/09/2011 | Battle Creek | USA | Left | Left | 6' 1" | 205 lbs | $900,000 |
| Steeneveld, Frank | 3B | Buckhead Bowties | 18 | 01/01/2022 | Tera Cora | CUR | Right | Right | 6' 1" | 180 lbs | - |
| Steur, Gustaf | SP | Houston 1837 BBC | 17 | 08/21/2023 | Willemstad | CUR | Left | Right | 6' 6" | 195 lbs | - |
| Steur, Phil | RP | Houston 1837 BBC | 22 | 05/24/2018 | Zwartewaterland | NED | Switch | Right | 6' 0" | 175 lbs | $280,000 |
| Studdard, Antoine | 1B | Brooklyn Dodgers | 26 | 12/17/2014 | Newark | USA | Left | Right | 6' 0" | 205 lbs | $280,000 |
| Stuterberg, Harry | SP | Panama City Piranhas | 30 | 10/06/2010 | New York | USA | Right | Right | 6' 2" | 205 lbs | $2,200,000 |
| Sweemey, Onson | CL | Long Island Lighthouse | 31 | 05/09/2009 | Perris | USA | Left | Left | 6' 6" | 230 lbs | $4,300,000 |
| Szema, Ming-an | 1B | Long Island Lighthouse | 16 | 01/06/2024 | Putai | TPE | Right | Right | 6' 0" | 180 lbs | - |
