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| Name | Pos | Team | Age | DOB | POB | Nationality | Bats | Throws | Height | Weight | Salary |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Saelices, Juan Andrés | RP | Athletic Club KC U-24 | 20 | 09/07/2020 | Gorham | USA | Right | Right | 6' 0" | 185 lbs | - |
| Salas, Lúcio | SP | Levittown Blue Dragons | 24 | 01/02/2016 | Caracas | VEN | Right | Right | 6' 2" | 200 lbs | - |
| Salinas, Juan | RP | Columbia River Rats | 23 | 08/10/2017 | Aibonito | PUR | Left | Right | 6' 1" | 185 lbs | - |
| San Pedro, Tony | C | Yucca Valley Yellows | 19 | 04/29/2021 | San Pedro Sula | HON | Left | Right | 6' 0" | 180 lbs | - |
| Sanford, Joshua | RF | Levittown Blue Dragons | 23 | 05/08/2017 | Columbus | USA | Left | Left | 6' 5" | 220 lbs | - |
| Saromi, Sekien | RP | Grand Forks Caterpillars | 20 | 07/20/2020 | Narashino | JPN | Right | Right | 6' 3" | 190 lbs | - |
| Saunders, Carl | LF | Put-In-Bay BC | 24 | 05/24/2016 | Gresham | USA | Switch | Right | 6' 1" | 200 lbs | - |
| Schmidt, Kelvin | 1B | Grand Forks Caterpillars | 21 | 08/06/2019 | Cul De Sac | SIM | Left | Right | 6' 1" | 200 lbs | - |
| Schulte, Steffen | CF | Yucca Valley Yellows | 22 | 07/01/2018 | Dallastown | USA | Right | Right | 6' 0" | 185 lbs | - |
| Scott, Elijah | 1B | Yucca Valley Yellows | 20 | 04/14/2020 | Kennesaw | USA | Left | Left | 6' 2" | 205 lbs | - |
| Scott, Morton | 2B | Athletic Club KC U-24 | 21 | 01/29/2019 | Paris | USA | Right | Right | 6' 0" | 180 lbs | - |
| Searle, Stu | CL | Belleville Bulls | 21 | 09/09/2019 | Ottawa | CAN | Left | Right | 6' 3" | 205 lbs | - |
| Secada, Diego Alejandro | 1B | Caldwell Chiefs | 23 | 05/25/2017 | Desemparados | CRC | Switch | Right | 6' 5" | 230 lbs | - |
| Sellers, Cameron | SP | Put-In-Bay BC | 24 | 07/22/2016 | Pasco | USA | Right | Right | 6' 1" | 200 lbs | - |
| Sepúlveda, Alfredo | C | Belleville Bulls | 21 | 01/25/2019 | Barquisimeto | VEN | Right | Right | 6' 2" | 200 lbs | - |
| Shades, Sanford | SP | Caldwell Chiefs | 24 | 09/21/2016 | Inver Grove Heights | USA | Right | Right | 6' 2" | 205 lbs | - |
| Shimizu, Hirokumi | RP | Caldwell Chiefs | 24 | 10/26/2016 | Nagoya | JPN | Right | Right | 6' 3" | 205 lbs | - |
| Silva, Manuel | RP | Kennesaw Jets | 21 | 06/02/2019 | Nirgua | VEN | Left | Left | 5' 11" | 165 lbs | - |
| Simmons, Jerry | 2B | Idaho Falls Chukars | 24 | 10/04/2016 | Eagle Lake | USA | Right | Right | 6' 4" | 205 lbs | - |
| Sin, Man-su | LF | Levittown Blue Dragons | 22 | 03/13/2018 | Sunchon | PRK | Left | Left | 6' 2" | 185 lbs | - |
| Sinclair, Max | RF | Louisiana Dragoons | 21 | 02/21/2019 | North Canton | USA | Left | Left | 6' 1" | 175 lbs | - |
| Skinner, Jason | RP | Columbia River Rats | 23 | 09/02/2017 | Monongahela | USA | Right | Right | 5' 10" | 180 lbs | - |
| Smith, Josh | RP | Kennesaw Jets | 20 | 02/16/2020 | Villas | USA | Right | Left | 6' 2" | 195 lbs | - |
| Smith, Micheal | RP | Columbia River Rats | 21 | 03/02/2019 | Los Angeles | USA | Right | Right | 5' 11" | 180 lbs | - |
| St. John, John | SP | Levittown Blue Dragons | 24 | 04/09/2016 | Scott | USA | Switch | Right | 6' 0" | 190 lbs | - |
| Stam, Danny | SP | Louisiana Dragoons | 25 | 11/18/2015 | Willemstad | CUR | Right | Right | 6' 4" | 200 lbs | - |
| Suárez, Roberto | C | Washington Generals | 20 | 04/13/2020 | Buenos Aires | ARG | Right | Right | 6' 4" | 220 lbs | - |
| Suisha, Yasunobu | SP | Louisiana Dragoons | 22 | 03/24/2018 | Kimitsu | JPN | Left | Left | 6' 6" | 210 lbs | - |
| Sullivan, Patrick | 2B | Put-In-Bay BC | 22 | 12/22/2018 | Tucson | USA | Switch | Right | 6' 0" | 185 lbs | - |
