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| Name | Pos | Team | Age | DOB | POB | Nationality | Bats | Throws | Height | Weight | Salary |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Sakei, Masahiro | SP | Panama City Piranhas | 32 | 08/17/2007 | Futtsu | JPN | Switch | Right | 6' 6" | 220 lbs | $700,000 |
| Salcido, Carlos | RP | Panama City Piranhas | 29 | 09/23/2010 | El Cercado | DOM | Right | Right | 5' 10" | 165 lbs | $650,000 |
| Salinas, José | 3B | Echo Park Lakers | 28 | 08/23/2011 | Indianapolis | USA | Right | Right | 6' 0" | 200 lbs | $280,000 |
| Salt, Jack | RP | Kingston Township Knights | 28 | 03/29/2011 | Manassas | USA | Right | Right | 6' 4" | 215 lbs | $631,400 |
| Sánchez, Arturo | SP | Toledo Stingers | 17 | 10/27/2022 | Chilibre | PAN | Right | Right | 6' 1" | 175 lbs | - |
| Sánchez, Arturo | SP | Mississippi Mockingbirds | 18 | 10/23/2021 | Manizales | COL | Right | Right | 6' 2" | 180 lbs | - |
| Sánchez, Javier | 1B | Montana Pandas | 35 | 03/01/2004 | Villa Vazquez | DOM | Left | Left | 6' 5" | 285 lbs | $1,750,000 |
| Sanders, Bob | CF | Mississippi Mockingbirds | 28 | 09/07/2011 | Kansas City | USA | Left | Left | 5' 10" | 190 lbs | $406,000 |
| Sandoval, Fernando | SP | Toledo Stingers | 17 | 03/12/2022 | Turrialba | CRC | Right | Right | 6' 2" | 170 lbs | - |
| Santegoeds, Buddy | SP | Toledo Stingers | 16 | 03/16/2023 | Princess Quarter | SIM | Right | Right | 6' 1" | 170 lbs | - |
| Santos, José | SP | Long Island Lighthouse | 19 | 09/08/2020 | San Rafael Abajo | CRC | Right | Right | 6' 3" | 175 lbs | - |
| Sanu, Shiki | 3B | Athletic Club KC | 32 | 05/29/2007 | Sapporo | JPN | Switch | Right | 6' 1" | 205 lbs | $280,000 |
| Sapinoso, Juan | RF | Panama City Piranhas | 17 | 05/27/2022 | Puerto Plata | DOM | Left | Left | 6' 1" | 175 lbs | - |
| Sardinha, Guaspar | C | D.C. Divided | 16 | 09/19/2023 | Carapicuíba | BRA | Right | Right | 6' 5" | 205 lbs | - |
| Sassetti, Timoteo | RP | Houston 1837 BBC | 28 | 12/30/2011 | Caltanissetta | ITA | Right | Right | 5' 10" | 175 lbs | $280,000 |
| Savinon, Pepe | LF | Hollywood Shredders | 18 | 05/11/2021 | Culiacan | MEX | Right | Right | 6' 1" | 175 lbs | - |
| Sawyer, Davis | SP | Free Agent | 28 | 03/21/2011 | Shawnee | USA | Right | Right | 6' 5" | 230 lbs | - |
| Scantlebury, Arturo | 1B | Free Agent | 31 | 08/03/2008 | Graneros | CHI | Right | Right | 6' 0" | 205 lbs | - |
| Schaefer, John | LF | Echo Park Lakers | 31 | 03/19/2008 | Cincinnati | USA | Left | Left | 6' 2" | 235 lbs | $3,400,000 |
| Seco, Javier | 1B | Houston 1837 BBC | 25 | 08/01/2014 | Changuinola | PAN | Left | Left | 6' 3" | 225 lbs | $2,390,000 |
| Seitzinger, Wilfried | 2B | Panama City Piranhas | 18 | 08/25/2021 | Rincon | ANT | Left | Right | 6' 3" | 185 lbs | - |
| Sellers, Ricky | SP | Toledo Stingers | 24 | 01/28/2015 | Oro Valley | USA | Switch | Right | 6' 0" | 185 lbs | $280,000 |
| Serano, Pedro | 1B | Toledo Stingers | 25 | 05/13/2014 | Prairie Village | USA | Left | Left | 6' 6" | 245 lbs | $280,000 |
| Sharts, Owen | LF | Mississippi Mockingbirds | 30 | 08/14/2009 | Simi Valley | USA | Left | Left | 6' 0" | 210 lbs | $550,000 |
| Shepard, Bob | RP | Cleveland Browns | 30 | 12/12/2009 | Ellisville | USA | Right | Right | 6' 4" | 225 lbs | $621,600 |
| Sherman, Phil | C | Brooklyn Dodgers | 33 | 10/09/2006 | Claverack-Red Mills | USA | Right | Right | 6' 0" | 220 lbs | $1,000,000 |
| Shipp, Cameron | SP | Free Agent | 18 | 07/20/2021 | Anna's Retreat | VIR | Left | Left | 6' 5" | 190 lbs | - |
| Shmerkin, Yaakov | LF | Seattle Rocketeers | 24 | 01/20/2015 | Arara-BaNegev | ISR | Right | Right | 5' 10" | 180 lbs | $280,000 |
| Sidebottom, Marvin | RP | Panama City Piranhas | 27 | 09/09/2012 | Belmopan | BLZ | Right | Right | 6' 7" | 225 lbs | $2,040,000 |
| Silva, Ángel | SP | Toledo Stingers | 26 | 01/11/2013 | Santo Domingo | DOM | Left | Left | 5' 10" | 180 lbs | $1,200,000 |
| Silva, Luis | SP | Brooklyn Dodgers | 17 | 08/09/2022 | Mexico City | MEX | Left | Left | 6' 0" | 170 lbs | - |
| Silva, Roberto | RP | Montana Pandas | 35 | 08/11/2004 | Saginaw | USA | Right | Right | 6' 4" | 260 lbs | $7,800,000 |
| Sims, Chase | SP | Kingston Township Knights | 23 | 02/23/2016 | Baton Rouge | USA | Right | Left | 6' 0" | 180 lbs | $280,000 |
| Skelton, Ben | RP | Athletic Club KC | 32 | 10/25/2007 | Columbus | USA | Switch | Left | 6' 0" | 200 lbs | $420,000 |
| Smith, Adam | 1B | Houston 1837 BBC | 24 | 03/22/2015 | Haddington | SCO | Right | Right | 6' 1" | 185 lbs | $280,000 |
| Smith, Millard | RP | Houston 1837 BBC | 26 | 09/28/2013 | Albuquerque | USA | Switch | Right | 5' 11" | 190 lbs | $280,000 |
| Snider, Dale | RP | Kingston Township Knights | 29 | 02/21/2010 | Ridgefield Park | USA | Left | Left | 6' 6" | 230 lbs | $470,000 |
| Solís, Juan Carlos | C | Echo Park Lakers | 18 | 05/17/2021 | La Chorrera | PAN | Right | Right | 6' 2" | 185 lbs | - |
| Sperber, Murray | RF | Free Agent | 28 | 04/09/2011 | Battle Creek | USA | Left | Left | 6' 1" | 205 lbs | - |
| Steele, Morton | RP | Mississippi Mockingbirds | 29 | 09/04/2010 | Carmichael | USA | Left | Right | 6' 4" | 230 lbs | $454,000 |
| Steeneveld, Frank | 3B | Buckhead Bowties | 17 | 01/01/2022 | Tera Cora | CUR | Right | Right | 6' 1" | 180 lbs | - |
| Steur, Vaclav | 1B | Buffalo White Walkers | 19 | 12/23/2020 | Oranjestad | ARU | Right | Right | 6' 6" | 220 lbs | - |
| Stevenson, Shawn | RP | Free Agent | 29 | 03/15/2010 | Camden | USA | Right | Right | 6' 6" | 230 lbs | - |
| Stuterberg, Harry | SP | Panama City Piranhas | 29 | 10/06/2010 | New York | USA | Right | Right | 6' 2" | 205 lbs | $2,200,000 |
| Swetnam, Edward | SP | Houston 1837 BBC | 18 | 06/22/2021 | Charlotte Amalie | VIR | Right | Right | 6' 2" | 185 lbs | - |
