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| Name | Pos | Team | Age | DOB | POB | Nationality | Bats | Throws | Height | Weight | Salary |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Salazar, José | CL | Bethesda Atoms | 22 | 06/05/2016 | Las Tunas | CUB | Right | Right | 6' 1" | 180 lbs | - |
| Sánchez, Jesús | C | Richland Rails | 25 | 09/23/2013 | La Cruz | CRC | Switch | Right | 6' 1" | 195 lbs | - |
| Sánchez, Mario | RP | Asheville Highlanders | 26 | 08/14/2012 | Caracas | VEN | Right | Right | 6' 8" | 220 lbs | - |
| Sánchez, Tony | C | Billings Polar Bears | 24 | 03/30/2014 | Las Matas de Farfan | DOM | Right | Right | 6' 1" | 205 lbs | - |
| Santiago, Rafael | RP | San Antonio BC | 25 | 10/27/2013 | Yara | CUB | Right | Right | 5' 11" | 185 lbs | - |
| Sato, Aki | CL | Ottawa Nationals | 25 | 04/20/2013 | Mito | JPN | Right | Right | 6' 2" | 215 lbs | - |
| Saunders, Carl | LF | Marquette Miners | 22 | 05/24/2016 | Gresham | USA | Switch | Right | 6' 1" | 195 lbs | - |
| Scanlan, Oakland | CL | Akron Blimps | 24 | 06/08/2014 | Salem | USA | Right | Right | 6' 8" | 235 lbs | - |
| Scribbner, Thom | 2B | Casper Ghosts | 22 | 11/21/2016 | Santa Cruz | USA | Right | Right | 6' 2" | 195 lbs | - |
| Scruggins, Carsello | RF | Asheville Highlanders | 24 | 07/18/2014 | Halawa | USA | Right | Right | 6' 1" | 200 lbs | - |
| Shannon, Rod | RP | Akron Blimps | 27 | 09/09/2011 | Middleburg Heights | USA | Right | Right | 6' 1" | 205 lbs | - |
| Shepard, Dave | SP | Casper Ghosts | 25 | 06/08/2013 | Millcreek | USA | Left | Left | 6' 2" | 200 lbs | - |
| Sierra, Albert | SP | Asheville Highlanders | 29 | 11/05/2009 | Fantino | DOM | Right | Right | 6' 2" | 200 lbs | - |
| Skerrett, Don | 3B | Asheville Highlanders | 27 | 06/07/2011 | Los Angeles | USA | Right | Right | 6' 0" | 220 lbs | - |
| Smith, Mark | SP | Belvedere Park Rawhides | 25 | 09/24/2013 | Madison | USA | Left | Left | 6' 1" | 190 lbs | - |
| Snoddy, Robert | SP | Asheville Highlanders | 28 | 08/21/2010 | Los Angeles | USA | Right | Right | 6' 2" | 220 lbs | - |
| Soisalo, Pellervo | RP | Durham Rapiers | 25 | 10/16/2013 | Komadi | HUN | Left | Left | 6' 4" | 195 lbs | - |
| Solís, Javier | RP | Belvedere Park Rawhides | 19 | 03/28/2019 | San Miguel Chicaj | GUA | Switch | Right | 6' 4" | 190 lbs | - |
| Solís, Júlio | CF | Richland Rails | 26 | 08/02/2012 | Buenos Aires | ARG | Left | Left | 6' 2" | 195 lbs | - |
| Soto, Luis | SP | Ottawa Nationals | 26 | 09/08/2012 | Cornwells Heights-Eddington | USA | Left | Left | 6' 2" | 210 lbs | - |
| Sousa, Rodrigo | SS | Athletic Club KC Academy | 25 | 06/18/2013 | Rosario | ARG | Right | Right | 6' 0" | 210 lbs | - |
| Sterling, Raheem | DH | Billings Polar Bears | 24 | 03/14/2014 | Kingston | JAM | Right | Right | 6' 2" | 210 lbs | - |
| Steur, Phil | RP | Belvedere Park Rawhides | 20 | 05/24/2018 | Zwartewaterland | NED | Switch | Right | 6' 0" | 170 lbs | - |
| Stones, Rutland | RP | San Antonio BC | 25 | 02/12/2013 | Apache Junction | USA | Right | Right | 6' 0" | 195 lbs | - |
| Strickland, Marvin | 1B | Durham Rapiers | 28 | 12/20/2010 | Valle Vista | USA | Right | Right | 6' 4" | 260 lbs | - |
