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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | ERA | YEAR | Open Season Leaderboard |
|---|---|---|---|---|
| 1 | Todd Hines* | 2.52 | 2018-2032 | |
| 2 | Sozen Raikatuji | 2.59 | 2016-2023 | |
| 3 | Ryan Davis* | 2.62 | 2015-2026 | |
| 4 | Devin Hinton | 2.66 | 2013-2023 | |
| 5 | Ryan Ray | 2.79 | 2013-2021 | |
| 5 | Jesús Franco# | 2.79 | 2026-2033 | |
| 7 | Iván García | 2.82 | 2021-2035 | |
| 8 | Jim Eliott* | 2.83 | 2014-2025 | |
| 9 | Guillermo García | 2.85 | 2013-2021 | |
| 10 | Ralph McKinney | 2.88 | 2019-2034 | |
| 11 | Lúcio Sánchez | 2.90 | 2017-2031 | |
| 12 | Eric Matson# | 2.91 | 2028-2037 | |
| 13 | Yuri Volkers | 2.92 | 2013-2021 | |
| 14 | Jesús Caldero | 2.93 | 2018-2027 | |
| 15 | Bruce Wright | 2.95 | 2020-2030 | |
| 16 | Jorge Aguirre | 3.00 | 2015-2032 | |
| 17 | Jesús Gonzáles | 3.02 | 2019-2030 | |
| 17 | José Hernández | 3.02 | 2013-2023 | |
| 19 | Pedro Alejándrez | 3.04 | 2021-2034 | |
| 19 | Edwin Ellis | 3.04 | 2013-2019 | |
| 21 | Bill Oulton | 3.13 | 2021-2034 | |
| 21 | John Wilkins* | 3.13 | 2013-2028 | |
| 23 | Cris Mendoza | 3.15 | 2013-2029 | |
| 23 | John Kaufman | 3.15 | 2017-2032 | |
| 25 | Chester Henry | 3.16 | 2016-2023 | |
| 26 | Manuel Rojas | 3.17 | 2018-2028 | |
| 26 | Cordell Wilson | 3.17 | 2019-2030 | |
| 28 | Vincent Hall | 3.21 | 2020-2032 | |
| 28 | Ramón Ortega* | 3.21 | 2013-2028 | |
| 30 | Jorge Otero# | 3.22 | 2031-2037 | |
| 30 | Tom Reynolds* | 3.22 | 2015-2028 | |
| 32 | Yoriyoshi Yamamoto | 3.25 | 2016-2026 | |
| 33 | Gerardo Pagán# | 3.29 | 2027-2037 | |
| 33 | Edgardo Marín | 3.29 | 2013-2032 | |
| 35 | Alec Pittman | 3.31 | 2016-2030 | |
| 35 | Pedro Ortíz# | 3.31 | 2020-2037 | |
| 37 | Aurelio López# | 3.42 | 2022-2036 | |
| 38 | Juan Júlio | 3.45 | 2013-2026 | |
| 39 | Miguel Rubia# | 3.46 | 2029-2037 | |
| 40 | Raúl Gómez | 3.48 | 2027-2033 | |
| 40 | Wayne Craig | 3.48 | 2018-2030 | |
| 40 | Ilie Paunescu | 3.48 | 2016-2035 | |
| 43 | Curtis Fields | 3.49 | 2016-2024 | |
| 43 | Eddie Kop# | 3.49 | 2025-2037 | |
| 43 | George Frazier# | 3.49 | 2019-2037 | |
| 43 | John Dempsey | 3.49 | 2022-2037 | |
| 47 | Pat Farrell | 3.53 | 2013-2022 | |
| 48 | Wes Hamm | 3.55 | 2021-2037 | |
| 48 | Alejandro Guerra# | 3.55 | 2027-2037 | |
| 48 | Billy Crawford | 3.55 | 2014-2025 | |
| 51 | Germán Rodríguez# | 3.58 | 2024-2037 | |
| 52 | Wayne Hurst | 3.63 | 2015-2024 | |
| 53 | Fraser Cuevas | 3.64 | 2020-2032 | |
| 54 | Raúl Areola | 3.65 | 2020-2033 | |
| 55 | Keisuke Nishida | 3.66 | 2029-2036 | |
| 56 | Burt Booth | 3.67 | 2013-2026 | |
| 57 | Tony Alfonso# | 3.69 | 2033-2037 | |
| 57 | José García | 3.69 | 2022-2035 | |
| 59 | Enrique Cortéz | 3.70 | 2022-2032 | |
| 60 | Juan Torres | 3.71 | 2023-2029 | |
| 61 | Kirby Brown | 3.76 | 2017-2029 | |
| 62 | José Flores | 3.80 | 2019-2029 | |
| 63 | Bill Fletcher | 3.81 | 2018-2025 | |
| 63 | Mimosa Joseph | 3.81 | 2023-2035 | |
| 65 | Miguel Castillo | 3.82 | 2013-2020 | |
| 66 | Luis Flores | 3.83 | 2024-2033 | |
| 67 | Yoo-chul Mun# | 3.84 | 2031-2037 | |
| 68 | Giovanni Mireles# | 3.86 | 2029-2037 | |
| 69 | Ramón Molina | 3.89 | 2026-2034 | |
| 70 | Jaime van de Weideven# | 3.91 | 2022-2037 | |
| 71 | Mario Peńa | 3.98 | 2013-2023 | |
| 72 | Enrique Magana | 4.04 | 2013-2019 | |
| 73 | Josef van der Poel# | 4.05 | 2019-2035 | |
| 74 | Vern Camp | 4.08 | 2013-2022 | |
| 75 | Addie Samson | 4.11 | 2021-2035 | |
| 76 | Elroy Thompkins# | 4.15 | 2029-2037 | |
| 77 | Natalino Golaio# | 4.21 | 2023-2037 | |
| 78 | Sam Mooney# | 4.25 | 2028-2037 | |
| 79 | Tobías Pérez# | 4.27 | 2024-2037 | |
| 80 | Pablo De La Torre# | 4.31 | 2021-2037 | |
| 81 | Yin-fat Foong | 4.36 | 2017-2029 | |
| 81 | Cole Hall | 4.36 | 2013-2027 | |
| 83 | Sy-ing Tah# | 4.37 | 2030-2037 | |
| 84 | Calvin Beck | 4.45 | 2026-2033 | |
| 85 | Luis Peńa | 4.54 | 2025-2037 | |
| 85 | Gerald Keller# | 4.54 | 2030-2036 | |
| 87 | Edgar Martínez | 4.78 | 2013-2021 | |
| 88 | Pedro Ramírez | 5.08 | 2023-2032 |
