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| Name | Pos | Team | Age | DOB | POB | Nationality | Bats | Throws | Height | Weight | Salary |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Sa, Hyeon-uk | SP | Twinsburg Tigers | 20 | 08/12/2016 | Sangju | KOR | Left | Right | 6' 3" | 185 lbs | - |
| Sagal, Cortez | RP | Free Agent | 18 | 04/05/2018 | Davao | PHI | Right | Right | 6' 4" | 180 lbs | - |
| Salij, Vincent | RP | Free Agent | 18 | 04/10/2018 | Cul De Sac | SIM | Right | Right | 6' 2" | 180 lbs | - |
| Sánchez, Guillermo | C | Montgomery Biscuits | 18 | 10/08/2018 | San Juan Sacatepéquez | GUA | Right | Right | 6' 0" | 185 lbs | - |
| Sánchez, José | CF | Ballard Beavers | 19 | 10/14/2017 | Nicoya | CRC | Right | Right | 6' 2" | 190 lbs | - |
| Sanford, Tucker | CF | Franklin Fire | 19 | 11/23/2017 | Corner Brook | CAN | Right | Right | 5' 9" | 160 lbs | - |
| Santos, Juan | CF | Montgomery Biscuits | 18 | 02/19/2018 | San Salvador | SLV | Left | Left | 6' 3" | 180 lbs | - |
| Saunders, Carl | LF | Northwest Territory Beavers | 20 | 05/24/2016 | Gresham | USA | Switch | Right | 6' 1" | 195 lbs | - |
| Seth, Sadiya | CF | Twinsburg Tigers | 19 | 03/31/2017 | Bafata | GNB | Right | Left | 5' 11" | 165 lbs | - |
| Sheppard, Jeffrey | SP | Moose Jaw Canucks | 22 | 12/17/2014 | Los Angeles | USA | Right | Right | 5' 9" | 170 lbs | - |
| Sierra, Enrique | LF | Free Agent | 24 | 11/13/2012 | San Leandro | USA | Right | Right | 5' 9" | 180 lbs | - |
| Silva, Armando | CF | Indiana Lead Sox | 20 | 03/24/2016 | Santo Domingo | DOM | Right | Right | 5' 11" | 175 lbs | - |
| Slaughter, Lonnie | RP | Ballard Beavers | 21 | 10/08/2015 | Willimantic | USA | Right | Right | 6' 4" | 205 lbs | - |
| Slot, Sidney | SS | Twinsburg Tigers | 20 | 10/13/2016 | Willemstad | CUR | Right | Right | 6' 1" | 170 lbs | - |
| Sorensen, Marty | RP | Moose Jaw Canucks | 19 | 03/05/2017 | Wanganui | NZL | Right | Right | 6' 6" | 205 lbs | - |
| Soung, Sang-yeon | RP | Montgomery Biscuits | 18 | 01/25/2018 | Suji | KOR | Right | Right | 5' 9" | 155 lbs | - |
| Sparks, Stephen | 1B | Indiana Lead Sox | 20 | 02/07/2016 | Lackland AFB | USA | Right | Right | 6' 2" | 210 lbs | - |
| Speranza, Paolo | RP | Montgomery Biscuits | 20 | 10/30/2016 | Valencia | VEN | Switch | Left | 5' 10" | 165 lbs | - |
| Stam, Danny | SP | Amarillo Submarinos | 21 | 11/18/2015 | Willemstad | CUR | Right | Right | 6' 4" | 195 lbs | - |
| Starr, Joe | RP | Indiana Lead Sox | 18 | 03/29/2018 | Lake Grove | USA | Right | Right | 6' 0" | 170 lbs | - |
| Strong, Justin | SS | Moose Jaw Canucks | 18 | 07/01/2018 | Lake Worth | USA | Right | Right | 6' 0" | 175 lbs | - |
| Subramanya, Cakaraka | SP | Tulsa Otters | 19 | 01/13/2017 | Koyampattur | IND | Switch | Right | 6' 5" | 185 lbs | - |
| Suisha, Yasunobu | SP | Amarillo Submarinos | 18 | 03/24/2018 | Kimitsu | JPN | Left | Left | 6' 6" | 195 lbs | - |
