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| Name | Pos | Team | Age | DOB | POB | Nationality | Bats | Throws | Height | Weight | Salary |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Sabadodíaz, Wilson | RF | Olympia Ogres | 22 | 12/13/2014 | Telluride | USA | Left | Left | 6' 1" | 190 lbs | - |
| Sánchez, Carlos | C | Olympia Ogres | 21 | 11/08/2015 | Bay Point | USA | Left | Right | 6' 0" | 185 lbs | - |
| Sánchez, Juan | RF | Richland Rails | 27 | 08/07/2009 | Higüey | DOM | Right | Right | 6' 2" | 220 lbs | - |
| Santiago, Arturo | RP | Billings Polar Bears | 24 | 09/22/2012 | West Cape May | USA | Right | Right | 6' 2" | 195 lbs | - |
| Schmidt, Doug | RP | Ithaca Fighting Imps | 26 | 04/26/2010 | Sangerville | USA | Switch | Right | 6' 2" | 200 lbs | - |
| Seim, Shane | 3B | Asheville Highlanders | 28 | 11/22/2008 | Massillon | USA | Right | Right | 6' 1" | 210 lbs | - |
| Sellers, Ricky | CF | Olympia Ogres | 21 | 01/28/2015 | Oro Valley | USA | Switch | Right | 6' 0" | 180 lbs | - |
| Shan, Wei | SP | Asheville Highlanders | 28 | 07/14/2008 | Zhaoqing | CHN | Switch | Right | 6' 8" | 240 lbs | - |
| Simon, Frank | C | Richland Rails | 25 | 04/01/2011 | New Port Richey East | USA | Right | Right | 6' 1" | 225 lbs | - |
| Skerrett, Don | 3B | Asheville Highlanders | 25 | 06/07/2011 | Los Angeles | USA | Right | Right | 6' 0" | 210 lbs | - |
| Snider, Roy | CF | San Antonio BC | 24 | 12/08/2012 | East Los Angeles | USA | Switch | Left | 6' 0" | 185 lbs | - |
| Snoddy, Robert | RP | Asheville Highlanders | 26 | 08/21/2010 | Los Angeles | USA | Right | Right | 6' 2" | 210 lbs | - |
| Soisalo, Pellervo | RP | Durham Rapiers | 23 | 10/16/2013 | Komadi | HUN | Left | Left | 6' 4" | 180 lbs | - |
| Sokolov, Bogdon | RP | Ithaca Fighting Imps | 28 | 05/20/2008 | Leningradskaya | RUS | Right | Right | 6' 5" | 200 lbs | - |
| Sorensen, Leon | RP | Durham Rapiers | 27 | 09/28/2009 | Clarksville | USA | Right | Right | 5' 10" | 190 lbs | - |
| Sorrell, Liam | RP | San Antonio BC | 26 | 09/06/2010 | Anna's Retreat | VIR | Right | Right | 5' 10" | 160 lbs | - |
| Soto, Ismael | RF | Olympia Ogres | 22 | 10/28/2014 | New York | USA | Left | Left | 6' 5" | 205 lbs | - |
| Soto, Luis | SP | Ottawa Nationals | 24 | 09/08/2012 | Cornwells Heights-Eddington | USA | Left | Left | 6' 2" | 200 lbs | - |
| Sousa, Rodrigo | SS | Athletic Club KC Academy | 23 | 06/18/2013 | Rosario | ARG | Right | Right | 6' 0" | 200 lbs | - |
| Spitsbaard, Pieter | RP | Virginia Beach Whales | 28 | 08/10/2008 | Willemstad | CUR | Right | Right | 6' 1" | 190 lbs | - |
| Strickland, Marvin | 1B | Durham Rapiers | 26 | 12/20/2010 | Valle Vista | USA | Right | Right | 6' 4" | 250 lbs | - |
| Sun, Hui-ying | CF | Richland Rails | 25 | 05/05/2011 | Luchou | TPE | Right | Right | 6' 4" | 205 lbs | - |
