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| Name | Pos | Team | Age | DOB | POB | Nationality | Bats | Throws | Height | Weight | Salary |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Salas, Alberto | CF | Calgary Lynx | 30 | 05/23/2004 | Cardenas | CUB | Right | Right | 5' 9" | 180 lbs | - |
| Salazar, Jesús | RP | Pawnee ParksNRec | 30 | 10/09/2004 | Santo Domingo | DOM | Left | Left | 6' 1" | 210 lbs | - |
| Samurakami, Yoshihito | C | Bakersfield Nobles | 32 | 05/16/2002 | Takasago | JPN | Right | Right | 6' 5" | 280 lbs | $650,000 |
| Sánchez, Albert | 1B | Free Agent | 31 | 02/22/2003 | Santo Domingo | DOM | Switch | Right | 6' 2" | 230 lbs | - |
| Sánchez, Carlos | SP | Pawnee ParksNRec | 33 | 06/04/2001 | Maracaibo | VEN | Left | Left | 6' 2" | 230 lbs | $12,930,000 |
| Sánchez, Carlos | 2B | Scranton Supernovas | 34 | 11/07/2000 | Carolina | PUR | Switch | Right | 6' 0" | 230 lbs | $280,000 |
| Sánchez, Juan | SP | Bakersfield Nobles | 23 | 07/22/2011 | Santo Domingo | DOM | Right | Right | 6' 3" | 175 lbs | - |
| Sánchez, Juan | RP | Free Agent | 26 | 10/03/2008 | Chaska | USA | Left | Right | 6' 0" | 190 lbs | - |
| Sánchez, Manuel | RP | Bakersfield Nobles | 23 | 11/19/2011 | Songo-La Maya | CUB | Left | Right | 6' 0" | 200 lbs | $1,640,000 |
| Sandoval, Francisco | RP | Santa Barbara Golden Cranes | 29 | 01/15/2005 | Jalapa | GUA | Right | Right | 6' 1" | 205 lbs | - |
| Santiago, Félix | RP | Ellenburg Fighting Dachsunds | 28 | 02/02/2006 | La Romana | DOM | Right | Right | 6' 2" | 200 lbs | - |
| Santos, Francisco | 2B | Free Agent | 32 | 06/03/2002 | Guadalupe | COL | Left | Right | 6' 1" | 220 lbs | - |
| Sato, Yoichibei | RF | Free Agent | 35 | 11/12/1999 | Urayasu | JPN | Left | Left | 6' 3" | 215 lbs | - |
| Scalabrine, Brian | SP | Florida Men | 33 | 06/21/2001 | Berkeley Lake | USA | Right | Right | 5' 11" | 210 lbs | - |
| Schneider, Jeff | RP | Scranton Supernovas | 34 | 06/03/2000 | Cincinnati | USA | Right | Left | 6' 3" | 200 lbs | $280,000 |
| Scorpio, Hank | RF | Santa Barbara Golden Cranes | 33 | 01/25/2001 | Springfield | USA | Right | Right | 6' 1" | 215 lbs | - |
| Seah, Jin-song | CF | Santa Barbara Golden Cranes | 27 | 03/28/2007 | Taichung | TPE | Left | Left | 6' 2" | 200 lbs | - |
| Shelton, Ken | RP | Free Agent | 34 | 07/28/2000 | Norfolk | USA | Right | Right | 6' 8" | 235 lbs | - |
| Silander, Chad | 2B | Pawnee ParksNRec | 26 | 06/09/2008 | Salmon Arm | CAN | Right | Right | 6' 0" | 195 lbs | $280,000 |
| Silva, Fernando | LF | Free Agent | 33 | 02/21/2001 | Las Matas de Farfan | DOM | Right | Right | 6' 1" | 205 lbs | - |
| Simmons, Earl | SP | Florida Men | 33 | 02/12/2001 | Mt. Vernon | USA | Right | Right | 6' 0" | 190 lbs | - |
| Singletary, Norm | 2B | Ellenburg Fighting Dachsunds | 30 | 01/17/2004 | New York | USA | Switch | Right | 6' 2" | 215 lbs | - |
| Smiley, Mark | LF | Bloomington Longnecks | 32 | 03/03/2002 | San Diego | USA | Right | Right | 6' 2" | 240 lbs | - |
| Snigdha, Dhyana | SS | Calgary Lynx | 26 | 03/13/2008 | Palitana | IND | Right | Right | 6' 3" | 210 lbs | $280,000 |
| Solís, Alonso | SS | Scranton Supernovas | 34 | 10/29/2000 | Cabudare | VEN | Switch | Right | 6' 1" | 210 lbs | - |
| Sosa, Dave | 2B | Calgary Lynx | 25 | 09/15/2009 | Ozark | USA | Right | Right | 6' 1" | 200 lbs | - |
| Soto, Eric | RF | Bloomington Longnecks | 22 | 03/11/2012 | Springfield | USA | Switch | Left | 6' 0" | 205 lbs | - |
| Spencer, J.J. | RP | Free Agent | 29 | 07/14/2005 | Tonawanda CDP | USA | Left | Right | 5' 10" | 210 lbs | - |
| St. James, Ed | SS | Santa Barbara Golden Cranes | 29 | 06/25/2005 | Reno | USA | Right | Right | 6' 0" | 205 lbs | - |
| Stackhouse, Geoff | SP | Bloomington Longnecks | 26 | 11/05/2008 | Langport | ENG | Right | Right | 6' 2" | 195 lbs | - |
| Stark, Ed | RP | Free Agent | 35 | 09/14/1999 | Madera | USA | Right | Right | 6' 1" | 205 lbs | - |
| Striker, Ted | LF | Free Agent | 31 | 03/27/2003 | Fayetteville | USA | Switch | Right | 5' 10" | 220 lbs | - |
| Sutherland, Jack | 2B | Free Agent | 32 | 07/24/2002 | Winton | USA | Left | Right | 6' 3" | 225 lbs | - |
| Sutkamp, Ulbert | 3B | Bakersfield Nobles | 32 | 03/19/2002 | Borne | NED | Right | Right | 6' 1" | 215 lbs | $8,070,000 |
