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| Name | Pos | Team | Age | DOB | POB | Nationality | Bats | Throws | Height | Weight | Salary |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Sachs, Eddie | 1B | Philadelphia 1776 BC | 27 | 09/27/2007 | Allentown | USA | Right | Right | 6' 1" | 235 lbs | $280,000 |
| Sai, Seishiro | RP | Free Agent | 34 | 12/05/2000 | Yamato | JPN | Right | Right | 6' 1" | 220 lbs | - |
| Saito, Katsunan | SP | Vancouver Grey Wolves | 17 | 02/12/2017 | Hakodate | JPN | Right | Right | 6' 5" | 190 lbs | - |
| Salas, Lúcio | SP | Phoenix Hotspur | 18 | 01/02/2016 | Caracas | VEN | Right | Right | 6' 2" | 185 lbs | - |
| Salazar, Roberto | RF | Boston Patriots | 35 | 08/01/1999 | Pizarrete | DOM | Left | Left | 6' 2" | 205 lbs | $1,280,000 |
| Salt, Jack | RP | Northern Virginia Rainbow Mermaids | 23 | 03/29/2011 | Manassas | USA | Right | Right | 6' 4" | 210 lbs | $280,000 |
| Samson, Addie | SP | Portland Evergreens | 34 | 03/01/2000 | Westerveld | NED | Left | Left | 6' 1" | 215 lbs | $7,250,000 |
| San Martín, Sergio | SS | Free Agent | 22 | 09/25/2012 | Bedford | USA | Right | Right | 5' 9" | 170 lbs | - |
| Sánchez, António | SP | Phoenix Hotspur | 19 | 05/25/2015 | Guacara | VEN | Left | Left | 5' 8" | 155 lbs | - |
| Sánchez, José | SP | Free Agent | 23 | 11/28/2011 | Nashville | USA | Right | Right | 6' 4" | 220 lbs | - |
| Sánchez, José | RP | Boston Patriots | 31 | 10/09/2003 | David | PAN | Left | Left | 6' 3" | 205 lbs | $1,150,000 |
| Sánchez, Miguel | SP | Free Agent | 20 | 11/21/2014 | Macon | USA | Right | Right | 5' 8" | 160 lbs | - |
| Sánchez, Rafael | RF | Philadelphia 1776 BC | 31 | 02/10/2003 | San Cristóbal | DOM | Left | Left | 6' 3" | 240 lbs | $280,000 |
| Sánchez, Roberto | RP | Free Agent | 21 | 03/17/2013 | Brentwood | USA | Left | Left | 6' 2" | 195 lbs | - |
| Sanders, Chris | SP | Free Agent | 20 | 11/05/2014 | Security-Widefield | USA | Right | Right | 6' 1" | 190 lbs | - |
| Sanders, Howard | 2B | Free Agent | 19 | 11/19/2015 | Youngstown | USA | Right | Right | 5' 10" | 170 lbs | - |
| Sanders, Jason | SP | Free Agent | 22 | 12/12/2012 | Prichard | USA | Right | Right | 6' 2" | 205 lbs | - |
| Santos, Juan | CF | Boston Patriots | 16 | 02/19/2018 | San Salvador | SLV | Left | Left | 6' 3" | 175 lbs | - |
| Santos, Pablo | SS | Las Vegas Flamingos | 18 | 02/15/2016 | San Vicente | SLV | Right | Right | 6' 1" | 170 lbs | - |
| Sarcoma, Broderick | 2B | Free Agent | 20 | 08/13/2014 | Mayagüez | PUR | Right | Right | 5' 9" | 165 lbs | - |
| Sato, Aki | SP | Free Agent | 21 | 04/20/2013 | Mito | JPN | Right | Right | 6' 2" | 205 lbs | - |
| Satyavrat, Manoo | CF | Philadelphia 1776 BC | 29 | 08/15/2005 | Pehlad Pur Bangar | IND | Left | Left | 6' 1" | 195 lbs | $25,010,000 |
| Sauls, José | SP | Boston Patriots | 28 | 07/29/2006 | Rocklin | USA | Left | Right | 5' 8" | 185 lbs | $280,000 |
| Saunders, Carl | LF | Free Agent | 18 | 05/24/2016 | Gresham | USA | Switch | Right | 6' 0" | 185 lbs | - |
| Schaefer, John | RF | Portland Evergreens | 26 | 03/19/2008 | Cincinnati | USA | Left | Left | 6' 2" | 215 lbs | $650,000 |
| Schmidt, Garland | SP | Free Agent | 24 | 04/14/2010 | Chapel Hill | USA | Right | Right | 6' 1" | 205 lbs | - |
| Schreurs, Sidney | C | Boston Patriots | 18 | 10/06/2016 | Willemstad | CUR | Left | Right | 6' 3" | 205 lbs | - |
| Scott, Chris | SP | Free Agent | 23 | 07/28/2011 | Whetstone | USA | Left | Left | 6' 3" | 205 lbs | - |
| Scribbner, Thom | 2B | Free Agent | 18 | 11/21/2016 | Santa Cruz | USA | Right | Right | 6' 1" | 180 lbs | - |
| Secada, Diego Alejandro | 1B | St. Louis Coeur | 17 | 05/25/2017 | Desemparados | CRC | Switch | Right | 6' 5" | 210 lbs | - |
| Seco, Jesús | C | Free Agent | 24 | 12/08/2010 | South Bay | USA | Right | Right | 6' 0" | 195 lbs | - |
| Sexton, Jeb | SS | Chicago Gold Sox | 28 | 03/29/2006 | Joal-Fadiouth | SEN | Right | Right | 6' 2" | 195 lbs | $420,000 |
| Shelton, Garrett | SP | Free Agent | 18 | 05/14/2016 | Tampa | USA | Left | Left | 6' 0" | 175 lbs | - |
| Sheppard, Jeffrey | SP | Free Agent | 20 | 12/17/2014 | Los Angeles | USA | Right | Right | 5' 8" | 165 lbs | - |
| Shively, Roy | RP | Vancouver Grey Wolves | 31 | 09/16/2003 | Millbury | USA | Right | Right | 6' 3" | 220 lbs | $675,000 |
| Si, Yu-zeng | 3B | Buckhead Bowties | 24 | 06/17/2010 | Maanshan | CHN | Left | Right | 6' 2" | 205 lbs | $12,500,000 |
| Sierra, Enrique | CF | Free Agent | 22 | 11/13/2012 | San Leandro | USA | Right | Right | 5' 8" | 175 lbs | - |
| Silva, Rob | SP | Toledo Stingers | 29 | 02/28/2005 | Phoenix | USA | Switch | Right | 6' 1" | 215 lbs | $2,800,000 |
| Silva, Roberto | RP | D.C. Divided | 30 | 08/11/2004 | Saginaw | USA | Right | Right | 6' 4" | 250 lbs | $7,050,000 |
| Sin, Sang-mok | SP | Northern Virginia Rainbow Mermaids | 17 | 10/07/2017 | Seoul | KOR | Left | Right | 6' 3" | 190 lbs | - |
| Skipworth, Ray | SP | Vancouver Grey Wolves | 28 | 04/12/2006 | Milford | USA | Right | Right | 6' 1" | 200 lbs | $2,500,000 |
| Slaugh, Bryan | SP | Free Agent | 19 | 05/18/2015 | Draper | USA | Left | Right | 6' 1" | 185 lbs | - |
| Sloan, Paul | 1B | Free Agent | 22 | 11/07/2012 | Los Angeles | USA | Right | Right | 6' 1" | 215 lbs | - |
| Smith, Joe | SP | Free Agent | 18 | 10/15/2016 | San Francisco | USA | Left | Left | 6' 0" | 175 lbs | - |
| Smith, Mark | SP | Free Agent | 21 | 09/24/2013 | Madison | USA | Left | Left | 6' 1" | 195 lbs | - |
| Smith, Millard | CL | Free Agent | 21 | 09/28/2013 | Albuquerque | USA | Switch | Right | 5' 10" | 180 lbs | - |
| Snell, Thomas | SP | Free Agent | 24 | 03/30/2010 | Clemmons | USA | Right | Right | 6' 2" | 200 lbs | - |
| Socorro, Tommy | C | Northern Virginia Rainbow Mermaids | 27 | 12/26/2007 | Fayetteville | USA | Right | Right | 6' 0" | 210 lbs | $900,000 |
| Solís, Carlos | SP | Toledo Stingers | 17 | 06/19/2017 | Escazú | CRC | Left | Left | 6' 9" | 215 lbs | - |
| Solís, Jeff | RP | Portland Evergreens | 24 | 07/19/2010 | Collinsville | USA | Right | Right | 5' 10" | 185 lbs | $280,000 |
| Solíz, Tony | CL | Philadelphia 1776 BC | 30 | 01/12/2004 | Papantla | MEX | Right | Right | 6' 2" | 215 lbs | $3,000,000 |
| Sommer, Chris | SP | Northern Virginia Rainbow Mermaids | 32 | 11/04/2002 | Yeehaw Junction | USA | Left | Left | 6' 2" | 225 lbs | $280,000 |
| Sosa, Francisco | RP | Free Agent | 23 | 03/11/2011 | Columbia | USA | Left | Right | 6' 0" | 200 lbs | - |
| Soto, Fernando | CF | Free Agent | 18 | 10/17/2016 | Chicago | USA | Right | Right | 6' 1" | 185 lbs | - |
| Soto, Fernando | CF | Portland Evergreens | 17 | 12/01/2017 | Valencia | VEN | Left | Left | 6' 3" | 175 lbs | - |
| Soto, Jaime | SS | St. Louis Coeur | 19 | 12/20/2015 | Santiago | CHI | Right | Right | 6' 0" | 170 lbs | - |
| Spivey, Asher | RP | Toledo Stingers | 33 | 01/07/2001 | Dixmoor | USA | Left | Left | 6' 1" | 215 lbs | $14,000,000 |
| Srivastav, Abhipala | CF | Philadelphia 1776 BC | 17 | 05/08/2017 | Rohtak | IND | Right | Right | 6' 3" | 175 lbs | - |
| St. Brown, Amon-Ra | 2B | D.C. Divided | 26 | 08/28/2008 | New York | USA | Right | Right | 5' 10" | 185 lbs | $280,000 |
| Stephenson, Jim | SP | Free Agent | 18 | 06/19/2016 | Ormond-By-The-Sea | USA | Right | Right | 6' 4" | 195 lbs | - |
| Sterrenburg, Edward | 2B | Boston Patriots | 23 | 02/07/2011 | Willemstad | CUR | Switch | Right | 6' 3" | 185 lbs | $280,000 |
| Stewart, Steve | 1B | Free Agent | 20 | 11/03/2014 | Red Hill | USA | Right | Right | 6' 0" | 195 lbs | - |
| Strickland, Doug | 1B | Free Agent | 21 | 04/29/2013 | Fresno | USA | Left | Left | 6' 1" | 215 lbs | - |
| Subramanya, Cakaraka | SP | Northern Virginia Rainbow Mermaids | 17 | 01/13/2017 | Koyampattur | IND | Switch | Right | 6' 4" | 185 lbs | - |
| Suerte, Enreecko-Edilberto | SP | Boston Patriots | 17 | 08/30/2017 | Naval | PHI | Left | Left | 6' 9" | 205 lbs | - |
| Sullivan, Dave | C | Free Agent | 18 | 06/26/2016 | Arlington | USA | Switch | Right | 6' 2" | 210 lbs | - |
| Summey, Kent | SS | Philadelphia 1776 BC | 31 | 07/12/2003 | Minneapolis | USA | Right | Right | 6' 0" | 195 lbs | $470,000 |
| Sutkamp, Arnold | SP | Ft. Worth Cattlemen | 19 | 08/27/2015 | Dantumadeel | NED | Right | Right | 6' 2" | 180 lbs | - |
| Suto, Teika | SP | Phoenix Hotspur | 19 | 05/25/2015 | Kawasaki | JPN | Right | Left | 6' 3" | 190 lbs | - |
| Swain, Mike | SP | Free Agent | 24 | 05/19/2010 | Orem | USA | Right | Right | 6' 0" | 190 lbs | - |
| Sweetapple, Rudolph | 2B | Free Agent | 18 | 10/22/2016 | Niagara Falls | CAN | Right | Right | 5' 11" | 170 lbs | - |
