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| Name | Pos | Team | Age | DOB | POB | Nationality | Bats | Throws | Height | Weight | Salary |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Sakei, Masahiro | SP | Phoenix Hotspur Youth | 24 | 08/17/2007 | Futtsu | JPN | Switch | Right | 6' 6" | 215 lbs | - |
| Sakei, Yeijiro | RP | Free Agent | 20 | 05/24/2011 | Yawata | JPN | Right | Right | 6' 2" | 185 lbs | - |
| Salazar, Claudio | SP | Asheville Highlanders | 26 | 09/25/2005 | San Pedro de Macorís | DOM | Right | Right | 6' 8" | 230 lbs | - |
| Sampson, Braylen | C | Phoenix Hotspur Youth | 24 | 10/06/2007 | Navy Yard City | USA | Right | Right | 5' 9" | 205 lbs | - |
| Sánchez, Arturo | RF | Free Agent | 27 | 11/29/2004 | Arraijan | PAN | Right | Right | 6' 3" | 210 lbs | - |
| Sánchez, José | C | Free Agent | 32 | 11/19/1999 | Santo Domingo | DOM | Right | Right | 6' 2" | 225 lbs | - |
| Sánchez, Orlando | 1B | Free Agent | 32 | 09/04/1999 | Monte Cristi | DOM | Right | Left | 6' 2" | 225 lbs | - |
| Sánchez, Raúl | SP | Richland Rails | 23 | 10/20/2008 | Bajos de Haina | DOM | Right | Right | 5' 11" | 185 lbs | - |
| Sanderson, Neil | RF | Free Agent | 25 | 04/17/2006 | Shelby | USA | Right | Right | 6' 1" | 200 lbs | - |
| Sandoval, Manny | SP | Durham Rapiers | 21 | 02/05/2010 | Santo Domingo | DOM | Right | Right | 6' 3" | 200 lbs | - |
| Sandoval, Ricardo | SS | Tacoma Fur Traders | 25 | 09/03/2006 | Maracaibo | VEN | Right | Right | 6' 1" | 185 lbs | - |
| Santiago, José | SP | Phoenix Hotspur Youth | 27 | 06/10/2004 | Jarabacoa | DOM | Left | Left | 6' 2" | 200 lbs | - |
| Sauls, José | RP | Mercer Island Screaming Eagles | 25 | 07/29/2006 | Rocklin | USA | Left | Right | 5' 8" | 170 lbs | - |
| Scarborough, Edward | SP | Durham Rapiers | 25 | 04/20/2006 | San Antonio | USA | Left | Right | 6' 0" | 190 lbs | - |
| Scott, Kenny | SS | Phoenix Hotspur Youth | 29 | 04/07/2002 | Chelsea | USA | Left | Right | 6' 1" | 215 lbs | - |
| Segura, José | SS | Asheville Highlanders | 25 | 10/16/2006 | Maracaibo | VEN | Switch | Right | 6' 1" | 185 lbs | - |
| Serrano, Todd | RP | Asheville Highlanders | 23 | 03/12/2008 | Salinas | USA | Left | Left | 6' 4" | 205 lbs | - |
| Shaw, Dave | 2B | Free Agent | 28 | 11/17/2003 | Edgewater | USA | Right | Right | 6' 2" | 205 lbs | - |
| Sierra, Albert | SP | Richland Rails | 22 | 11/05/2009 | Fantino | DOM | Right | Right | 6' 2" | 180 lbs | - |
| Silva, José | LF | Free Agent | 30 | 02/26/2001 | El Seibo | DOM | Right | Right | 6' 0" | 195 lbs | - |
| Sima, Shih-k'ai | C | Richland Rails | 25 | 09/22/2006 | Shantou | CHN | Right | Right | 6' 1" | 215 lbs | - |
| Sims, Will | RP | Northville Eclipse | 27 | 06/09/2004 | Queens | USA | Left | Right | 5' 11" | 205 lbs | - |
| Sinclair, Mark | RP | Durham Rapiers | 31 | 06/20/2000 | Pacheco | USA | Right | Right | 6' 5" | 235 lbs | - |
| Small, Obadiah | RP | Free Agent | 27 | 08/22/2004 | Cape Coral | USA | Left | Right | 6' 0" | 190 lbs | - |
| Smehrik, Tony | SP | Richland Rails | 20 | 07/09/2011 | Rocky Mount | USA | Left | Left | 6' 2" | 190 lbs | - |
| Snigdha, Dhyana | SS | Minnesota Loons | 23 | 03/13/2008 | Palitana | IND | Right | Right | 6' 3" | 195 lbs | - |
| Solís, Alberto | SP | Phoenix Hotspur Youth | 25 | 05/14/2006 | Santiago | DOM | Right | Right | 6' 5" | 210 lbs | - |
| Sorkin, Brandon | SP | Asheville Highlanders | 23 | 08/02/2008 | Somers Point | USA | Right | Right | 6' 1" | 195 lbs | - |
| Souder, Larry | SP | Phoenix Hotspur Youth | 25 | 05/28/2006 | Little Rock | USA | Right | Right | 6' 2" | 205 lbs | - |
| Souza, José | 3B | Phoenix Hotspur Youth | 22 | 02/09/2009 | Tiquisate | GUA | Right | Right | 6' 2" | 195 lbs | - |
| St. Brown, Amon-Ra | 2B | Tacoma Fur Traders | 23 | 08/28/2008 | New York | USA | Right | Right | 5' 10" | 180 lbs | - |
| Sterrenburg, Edward | 2B | Mercer Island Screaming Eagles | 20 | 02/07/2011 | Willemstad | CUR | Switch | Right | 6' 3" | 175 lbs | - |
| Stidston, Jack | SS | Springfield Shooters | 22 | 04/04/2009 | Normandy Park | USA | Right | Right | 5' 11" | 180 lbs | - |
| Stone, Rob | RP | Free Agent | 34 | 04/17/1997 | Le Sueur | USA | Right | Right | 6' 2" | 230 lbs | - |
