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| Name | Pos | Team | Age | DOB | POB | Nationality | Bats | Throws | Height | Weight | Salary |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Saikawa, Yoshihito | 3B | Free Agent | 36 | 10/16/1991 | Kannabe | JPN | Right | Right | 6' 2" | 230 lbs | - |
| Salgado, Jorge | 1B | Hialeah Dodos | 24 | 12/29/2003 | Ibagué | COL | Right | Right | 6' 1" | 195 lbs | - |
| Salinas, José | SP | Scranton Supernovas | 31 | 12/30/1996 | San Jose | USA | Right | Right | 6' 7" | 260 lbs | - |
| Sánchez, Lorenzo | SP | Salt Lake City Buzz | 28 | 01/11/1999 | Puerto la Cruz | VEN | Left | Left | 6' 0" | 190 lbs | $2,600,000 |
| Sánchez, Lúcio | 1B | Santa Barbara Golden Cranes | 27 | 09/07/2000 | Santo Domingo | DOM | Right | Right | 6' 2" | 225 lbs | - |
| Sánchez, Manuel | RF | Hamilton Coyotes | 26 | 12/04/2001 | Matanzas | CUB | Left | Right | 6' 0" | 205 lbs | - |
| Sánchez, Reynaldo | SP | Hamilton Coyotes | 27 | 08/06/2000 | Ocumare del Tuy | VEN | Left | Left | 6' 3" | 185 lbs | $280,000 |
| Sanders, Israel | SS | Florida Men | 28 | 08/27/1999 | Dallas | USA | Right | Right | 6' 4" | 230 lbs | $280,000 |
| Sanders, Steve | RP | Free Agent | 30 | 12/27/1997 | Homosassa Springs | USA | Left | Right | 6' 2" | 195 lbs | - |
| Sargent, Bob | 1B | Hamilton Coyotes | 30 | 03/12/1997 | West Belmar | USA | Right | Right | 6' 1" | 240 lbs | $280,000 |
| Saunders, Wayne | 1B | Salt Lake City Buzz | 31 | 04/02/1996 | Irvine | USA | Switch | Right | 6' 2" | 215 lbs | $280,000 |
| Scalabrine, Brian | SP | Florida Men | 26 | 06/21/2001 | Berkeley Lake | USA | Right | Right | 5' 11" | 200 lbs | - |
| Schlosser, Randy | LF | Salt Lake City Buzz | 26 | 10/02/2001 | Fox Farm-College | USA | Left | Right | 5' 10" | 185 lbs | $280,000 |
| Schneider, Jeff | RP | Scranton Supernovas | 27 | 06/03/2000 | Cincinnati | USA | Right | Left | 6' 3" | 210 lbs | $280,000 |
| Serrano, António | RF | Augusta Timber Hawks | 23 | 07/12/2004 | Duvergé | DOM | Left | Left | 6' 5" | 210 lbs | - |
| Sharp, Frank | LF | Salt Lake City Buzz | 24 | 07/04/2003 | Erie | USA | Left | Left | 6' 3" | 205 lbs | - |
| Sharp, Monty | RF | Hamilton Coyotes | 29 | 05/02/1998 | West Valley | USA | Right | Right | 6' 0" | 190 lbs | - |
| Siebert, Leon | SP | Tremont Doubledays | 24 | 12/29/2003 | Shackelford | USA | Right | Right | 6' 4" | 210 lbs | $280,000 |
| Silva, Jorge | SP | Florida Men | 30 | 03/25/1997 | Valencia | VEN | Right | Right | 6' 2" | 210 lbs | - |
| Simmons, Alex | RP | Free Agent | 32 | 05/14/1995 | Brooklyn | USA | Switch | Right | 6' 0" | 195 lbs | - |
| Sims, Gerald | 2B | Hialeah Dodos | 27 | 03/11/2000 | New York | USA | Right | Right | 5' 9" | 190 lbs | - |
| Smiley, Mark | LF | Bloomington Longnecks | 25 | 03/03/2002 | San Diego | USA | Right | Right | 6' 2" | 215 lbs | - |
| Smith, Parker | SS | Brinkley Belugas | 26 | 12/21/2001 | Waverly | USA | Right | Right | 6' 3" | 215 lbs | - |
| Sobieski, Caleb | SP | Salt Lake City Buzz | 25 | 10/26/2002 | Rock Hill | USA | Right | Right | 6' 3" | 220 lbs | - |
| Solís, Alonso | SS | Scranton Supernovas | 27 | 10/29/2000 | Cabudare | VEN | Switch | Right | 6' 1" | 200 lbs | - |
| Sosa, Tom | RP | Free Agent | 32 | 03/18/1995 | Normal | USA | Right | Right | 6' 5" | 220 lbs | - |
| Soto, Jesús | 1B | Hamilton Coyotes | 28 | 07/31/1999 | Santiago | DOM | Right | Right | 6' 1" | 210 lbs | - |
| Soto, Roberto | 2B | Salt Lake City Buzz | 24 | 11/30/2003 | Anselmo Llorente | CRC | Left | Right | 6' 0" | 190 lbs | - |
| Spencer, J.J. | SP | Tremont Doubledays | 22 | 07/14/2005 | Tonawanda CDP | USA | Left | Right | 5' 10" | 185 lbs | - |
| St. James, Ed | SS | Santa Barbara Golden Cranes | 22 | 06/25/2005 | Reno | USA | Right | Right | 6' 0" | 185 lbs | - |
| Stanley, Donald | 2B | Free Agent | 32 | 01/30/1995 | Macomb Township | USA | Right | Right | 6' 0" | 190 lbs | - |
| Stanley, Tommy | RF | Free Agent | 30 | 08/30/1997 | Stanton | USA | Right | Right | 5' 11" | 195 lbs | - |
| Stoltzfus, Chris | LF | Free Agent | 30 | 08/06/1997 | Nashville | USA | Left | Left | 6' 0" | 210 lbs | - |
| Strolz, Josef | SP | Tremont Doubledays | 26 | 01/30/2001 | Unknown | AUT | Right | Right | 6' 3" | 200 lbs | $280,000 |
| Struck, Ty | 3B | Bloomington Longnecks | 25 | 07/08/2002 | Long Beach | USA | Right | Right | 6' 1" | 215 lbs | $280,000 |
| Suárez, Galtero | C | Augusta Timber Hawks | 21 | 04/02/2006 | Santo Domingo | DOM | Switch | Right | 6' 0" | 185 lbs | - |
| Suárez, Ricardo | SP | Augusta Timber Hawks | 23 | 03/21/2004 | Duvergé | DOM | Right | Right | 6' 6" | 205 lbs | - |
| Sullivan, Tommy | CF | Hamilton Coyotes | 25 | 12/17/2002 | New Brunswick | USA | Left | Left | 5' 9" | 185 lbs | - |
| Summey, Kent | SS | Scranton Supernovas | 24 | 07/12/2003 | Minneapolis | USA | Right | Right | 6' 0" | 195 lbs | - |
| Sutton, Joe | SS | Free Agent | 28 | 09/25/1999 | Benicia | USA | Left | Right | 6' 2" | 200 lbs | - |
